(R)-4-Benzyl-2-oxazolidinone
- CAS No.
- 102029-44-7
- Chemical Name:
- (R)-4-Benzyl-2-oxazolidinone
- Synonyms
- (R)-4-(PHENYLMETHYL)-2-OXAZOLIDINONE;RBOX;4-benzyl-2-0xazolidinone;(4R)-Phenylmethyl-2-oxazolidinone;R-BOZ;MLS00;TB-2044;TL806371;-2-oxazoL;(R)-4-BenzyL
- CBNumber:
- CB7852611
- Molecular Formula:
- C10H11NO2
- Molecular Weight:
- 177.2
- MDL Number:
- MFCD00010846
- MOL File:
- 102029-44-7.mol
- MSDS File:
- SDS
Melting point | 88-90 °C |
---|---|
alpha | 62 º (C=1, CHCl3) |
Boiling point | 309.12°C (rough estimate) |
Density | 1.1607 (rough estimate) |
refractive index | 14.5 ° (C=5, MeOH) |
storage temp. | Inert atmosphere,Room Temperature |
solubility | Chloroform (Slightly) |
form | Crystalline Powder |
pka | 12.78±0.40(Predicted) |
color | White to almost white |
optical activity | [α]18/D +64°, c = 1 in chloroform |
Water Solubility | Insoluble in water. Soluble in Chloroform. |
Sensitive | Hygroscopic |
BRN | 4782551 |
CAS DataBase Reference | 102029-44-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H320 | |||||||||
Precautionary statements | P264-P305+P351+P338+P337+P313 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 22-24/25-36-26 | |||||||||
WGK Germany | 3 | |||||||||
F | 3-10 | |||||||||
HS Code | 29349990 | |||||||||
NFPA 704 |
|
(R)-4-Benzyl-2-oxazolidinone price More Price(63)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 300977 | (R)-4-Benzyl-2-oxazolidinone 99% | 102029-44-7 | 5g | $24.68 | 2024-03-01 | Buy |
Sigma-Aldrich | 300977 | (R)-4-Benzyl-2-oxazolidinone 99% | 102029-44-7 | 1G | $35.8 | 2023-01-07 | Buy |
TCI Chemical | B1786 | (R)-4-Benzyl-2-oxazolidinone >98.0%(GC) | 102029-44-7 | 5g | $92 | 2024-03-01 | Buy |
TCI Chemical | B1786 | (R)-4-Benzyl-2-oxazolidinone >98.0%(GC) | 102029-44-7 | 25g | $297 | 2024-03-01 | Buy |
Alfa Aesar | A16770 | (R)-(+)-4-Benzyl-2-oxazolidinone, 99% | 102029-44-7 | 1g | $40.65 | 2024-03-01 | Buy |
(R)-4-Benzyl-2-oxazolidinone Chemical Properties,Uses,Production
Description
(R)-4-Benzyl-2-oxazolidinone is a derivative of oxazolidinone. It can be used in the preparation of enantiopure carbocyclic nucleosides, which act as a HIV protease inhibitor. It can also be used as a chiral auxiliary in the enantioselective synthesis of (2R, 2′S)-erythro-methylphenidate, beta-lactams and alpha-amino acids. Its end product includes asymmetric single isomeric drugs such as antitumor, anesthetic and entipasmodic products.
Chemical Properties
white to light yellow crystal powde
Uses
(R)-(+)-4-Benzyl-2-oxazolidinones are used in the enantioselective synthesis of beta-lactams and alpha-amino acids. End products can include asysmmetric single isomeric drugs of antitumor, anesthetic, antipasmodic products. Used in the synthesis of HIV protease inhibitors. An oxazolidinone used in chiral auxiliary asymetric synthesis.
Uses
intermediate for Aliskiren hemifumarate, Darifenacin HBr, Zolmitriptan
References
http://www.sigmaaldrich.com/catalog/product/aldrich/300977? lang=en®ion=US
https://www.alfa.com/en/catalog/A16770/ Shieh, Wen Chung, et al. "Synthesis of enantiomerically enriched 4- piperidinylglycine." US, US 6670477B2. 2003.
(R)-4-Benzyl-2-oxazolidinone Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12490 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5895 | 58 |
hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 | sales03@chemcn.cn | China | 973 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18628 | 58 |
Nanjing Gold Pharmaceutical Technology Co. Ltd. | 025-84209270 15906146951 | CHINA | 115 | 55 | |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21665 | 55 |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
Zjartschem | +86-571 87238903 | jocelynpan@zjarts.com | CHINA | 993 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
View Lastest Price from (R)-4-Benzyl-2-oxazolidinone manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-09-27 | (R)-4-Benzyl-2-oxazolidinone
102029-44-7
|
US $0.00 / kg | 1kg | 99%min | 20ton | Jinan Jianfeng Chemical Co., Ltd | ||
2024-09-26 | (R)-4-Benzyl-2-oxazolidinone
102029-44-7
|
US $9.00 / KG | 1KG | 99.9 | 1 ton | Hebei Chuanghai Biotechnology Co,.LTD | ||
2024-09-24 | (R)-4-Benzyl-2-oxazolidinone
102029-44-7
|
US $50.00 / kg | 1kg | 99% | 1000 | hebei hongtan Biotechnology Co., Ltd |
- (R)-4-Benzyl-2-oxazolidinone
102029-44-7
- US $0.00 / kg
- 99%min
- Jinan Jianfeng Chemical Co., Ltd
- (R)-4-Benzyl-2-oxazolidinone
102029-44-7
- US $9.00 / KG
- 99.9
- Hebei Chuanghai Biotechnology Co,.LTD
- (R)-4-Benzyl-2-oxazolidinone
102029-44-7
- US $50.00 / kg
- 99%
- hebei hongtan Biotechnology Co., Ltd
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