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4-Amino-1-butanol

4-Amino-1-butanol Structure
4-Amino-1-butanol structure
CAS No.
13325-10-5
Chemical Name:
4-Amino-1-butanol
Synonyms
4-aminobutan-1-ol;BUTANOLAMINE;4-AMINOBUTANOL;SKL271;N-ABU(4)-OL;H-ABUT(4)-OL;NH2-(CH2)4-OH;4-Aminobutanol-1;2-AcetyLhiophene;4-AMINO-1-BUTANOL
CBNumber:
CB7853047
Molecular Formula:
C4H11NO
Molecular Weight:
89.14
MDL Number:
MFCD00008230
MOL File:
13325-10-5.mol
MSDS File:
SDS
Last updated:2024-12-18 14:08:57
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4-Amino-1-butanol Properties

Melting point 16-18 °C (lit.)
Boiling point 206 °C (lit.)
Density 0.967 g/mL at 25 °C (lit.)
refractive index n20/D ~1.462(lit.)
Flash point 226 °F
storage temp. Store below +30°C.
solubility Acetonitrile (Slightly), Chloroform (Sparingly), Methanol (Slightly)
form Liquid
pka 15.10±0.10(Predicted)
color Clear colorless to slightly yellow
Water Solubility MISCIBLE
Sensitive Air Sensitive & Hygroscopic
BRN 1731411
Stability Unstable in Aqueous Solution
CAS DataBase Reference 13325-10-5(CAS DataBase Reference)
NIST Chemistry Reference NH2(CH2)4OH(13325-10-5)
EPA Substance Registry System 1-Butanol, 4-amino- (13325-10-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405
Hazard Codes  C
Risk Statements  34-22
Safety Statements  26-36/37/39-45-25
RIDADR  UN 2735 8/PG 3
WGK Germany  3
F  34
HazardClass  8
PackingGroup  III
HS Code  29221980
NFPA 704
1
3 1

4-Amino-1-butanol price More Price(37)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 178330 4-Amino-1-butanol 98% 13325-10-5 1g $39.9 2024-03-01 Buy
Sigma-Aldrich 178330 4-Amino-1-butanol 98% 13325-10-5 5g $113 2024-03-01 Buy
TCI Chemical A1013 4-Amino-1-butanol >98.0%(GC) 13325-10-5 5g $69 2024-03-01 Buy
TCI Chemical A1013 4-Amino-1-butanol >98.0%(GC) 13325-10-5 25g $274 2024-03-01 Buy
Alfa Aesar A12680 4-Amino-1-butanol, 98% 13325-10-5 1g $38.5 2023-06-20 Buy
Product number Packaging Price Buy
178330 1g $39.9 Buy
178330 5g $113 Buy
A1013 5g $69 Buy
A1013 25g $274 Buy
A12680 1g $38.5 Buy

4-Amino-1-butanol Chemical Properties,Uses,Production

Description

4-Amino-1-butanol (4AB) is an important pharmaceutical intermediate compound and a precursor of biodegradable polymers for gene delivery. It can be used in organic synthesis and biological properties studies, among others. In addition, 4-Amino-1-butanol (4AB) has been shown to have a higher CO2 solubility than 2-amino-1-ethanol (MEA), which is potentially useful in solving problems related to flue gas purification[1-2].

Chemical Properties

Very light clear yellow liquid

Uses

4-Amino-1-butanol was used:

  • As a linker in the synthesis of highly branched poly(β-amino esters)(HPAEs) for gene delivery.
  • As a side chain to modulate antimicrobial and hemolytic activities of copolymers.
  • In the total synthesis of (+)-fawcettimine,(+)-fawcettidine, and (?)-lycojapodine A.

Uses

4-Amino-1-butanol is a useful intermediate in a variety of organic synthesis. It is mainly used in personal-care products, preparation of water soluble cationic flocculants and ion exchange resins as well as in the preparation of beta-lactam antibiotics. It is used for the production of efficient anionic emulsifiers, nonionic polyethylene emulsions, water treatment, metal treatment and absorption of carbon dioxide gas. It is used as a pigment dispersion aid and curing agent in selected textile -resins.

Preparation

4-Amino-1-butanol (4AB) can be prepared by microbiological methods. we report for the first time the fermentative production of 4AB from glucose by metabolically engineered Corynebacterium glutamicum harboring a newly designed pathway comprising a putrescine (PUT) aminotransferase (encoded by ygjG) and an aldehyde dehydrogenase (encoded by yqhD) from Escherichia coli, which convert PUT to 4AB. Application of several metabolic engineering strategies such as fine-tuning the expression levels of ygjG and yqhD, eliminating competing pathways, and optimizing culture condition further improved 4AB production. Fed-batch culture of the final metabolically engineered C. glutamicum strain produced 24.7?g/L of 4AB[1].

References

[1] CINDY PRICILIA SURYA PRABOWO. Microbial production of 4-amino-1-butanol, a four-carbon amino alcohol[J]. Biotechnology and Bioengineering, 2020. DOI:10.1002/bit.27438.
[2] ZULKIFLI IDRIS . Equilibrium solubility of carbon dioxide in aqueous solutions of 3-amino-1-propanol, 4-amino-1-butanol and 5-amino-1-pentanol at low partial pressures[J]. Fluid Phase Equilibria, 2015. DOI:10.1016/j.fluid.2014.11.028.

4-Amino-1-butanol synthesis

24697-70-9
13325-10-5
Synthesis of 4-Amino-1-butanol from 2-(4-Hydroxybutyl)-2H-isoindole-1,3-dione

4-Amino-1-butanol Preparation Products And Raw materials

Raw materials

Acetonitrile N,N-Dimethylformamide Potassium hydroxide Acetyl chloride Zinc chloride
4-Chloro-1-butanol Hydrazine hydrate Tetrahydrofuran Diethyl ether Cobalt chloride
Potassium phthalimide 1H-Isoindole-1,3(2H)-dione, 2-[4-(acetyloxy)butyl]- 2-(4-Hydroxybutyl)-2H-isoindole-1,3-dione 4-aminobut-2-yn-1-ol hydrochloride Isobutyl nitrite
1,4-DIAMINOBUTANE 4-Aminobutyric acid

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Preparation Products

4-bromobutan-1-amine

4-Amino-1-butanol Suppliers

Global( 345)Suppliers
Supplier Tel Email Country ProdList Advantage
Suzhou Ryan Pharmachem Technology Co.,Ltd.
+86-512-68780025 +8618962125825 sales@ryanchem.com China 136 58
ROSEWA HOLDING GROUP CO.,LIMITED
+86-023-62871537 sales@rosewachem.com China 2827 58
Shanghai UCHEM Inc. 		+862156762820 +86-13564624040 sales@myuchem.com China 7629 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29791 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 18751 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
Shanghai Time Chemicals CO., Ltd. 		+86-021-57951555 +8617317452075 jack.li@time-chemicals.com China 1803 55
Hangzhou FandaChem Co.,Ltd. 		+8615858145714 FandaChem@Gmail.com China 9116 55
Nanjing ChemLin Chemical Industry Co., Ltd. 		025-83697070 product@chemlin.com.cn CHINA 3009 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29880 58
Supplier Advantage
Suzhou Ryan Pharmachem Technology Co.,Ltd.
58
ROSEWA HOLDING GROUP CO.,LIMITED
58
Shanghai UCHEM Inc. 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Shanghai Time Chemicals CO., Ltd. 		55
Hangzhou FandaChem Co.,Ltd. 		55
Nanjing ChemLin Chemical Industry Co., Ltd. 		60
career henan chemical co 		58

View Lastest Price from 4-Amino-1-butanol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Amino-1-butanol pictures 2024-11-14 4-Amino-1-butanol
13325-10-5
 US $980.00 / KG 1KG 98% 1-10mt Baoji Guokang Bio-Technology Co., Ltd.
4-Amino-1-butanol pictures 2024-11-01 4-Amino-1-butanol
13325-10-5
 US $18.00-332.00 / g 25g 0.98 500kg Shanghai UCHEM Inc.
4-Amino-1-butanol pictures 2023-05-12 4-Amino-1-butanol
13325-10-5
 US $0.00-0.00 / kg 10kg 98% ton grade Suzhou Ryan Pharmachem Technology Co.,Ltd.
  • 4-Amino-1-butanol pictures
  • 4-Amino-1-butanol
    13325-10-5
  • US $0.00-0.00 / kg
  • 98%
  • Suzhou Ryan Pharmachem Technology Co.,Ltd.

4-Amino-1-butanol Spectrum

4-Amino-1-butanol(13325-10-5)MS4-Amino-1-butanol(13325-10-5)1HNMR4-Amino-1-butanol(13325-10-5)13CNMR4-Amino-1-butanol(13325-10-5)IR14-Amino-1-butanol(13325-10-5)Raman

13325-10-5(4-Amino-1-butanol)Related Search:

4,4'-Diaminodiphenylsulfone 6-Aminocaproic acid Acetaminophen tert-Butanol ALTRENOGEST
Glucosamine Tris(hydroxymethyl)aminomethane 2-Butanol EC 2.6.1.2 Sulfamic acid
4-Dimethylaminopyridine 4-Amino-benzenesulfonic acid monosodium salt Glycine 1-Butanol (S)-(+)-2-Amino-1-butanol
1-AMINO-2-BUTANOL 4,4'-Azobis(4-cyanovaleric acid) Daminozide

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NH2-(CH2)4-OH N-ABU(4)-OL 4-HYDROXY-N-BUTYLAMINE 4-HYDROXYBUTYLAMINE 4-AMINO-1-BUTANOL 4-AMINOBUTYL ALCOHOL 4-AMINO-N-BUTYL ALCOHOL DELTA-AMINO-N-BUTYL ALCOHOL H-ABUT(4)-OL 4-Amino-1-Butanol98% 4-Aminobutane-1-ol 4-AMino-1-butanol, 98% 5GR 4-AMino-1-butanol 98% 1-Butanol, 4-amino- 4-Aminobutanol-1 4-hdyroxybutylamine 4-hydroxybutanamine H2NCH2(CH2)2CH2OH 4-hydroxybutylammonium 4-hydroxybutan-1-aminium 4-Amino-1-butanol > 4-AMINO-1-BUTANOL FOR SYNTHESIS 4-Amino-1-butanol USP/EP/BP SKL271 4-AMINOBUTANOL BUTANOLAMINE 4-aminobutan-1-ol 2-AcetyLhiophene 1-AMINO BUTANE-4-OL 13325-10-5 H2NCH24OH Amino Alcohols Building Blocks AMINE 蠅-Aminoalkanols 蠅-Functional Alkanols, Carboxylic Acids, Amines & Halides Organic Building Blocks Oxygen Compounds Amino Alcohols Building Blocks Chemical Synthesis Organic Building Blocks Oxygen Compounds omega-Aminoalkanols omega-Functional Alkanols, Carboxylic Acids, Amines & Halides Amino Alcohols Organic Building Blocks Oxygen Compounds Miscellaneous