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Octenidine dihydrochloride

Octenidine dihydrochloride structure

CAS No.: 70775-75-6

Chemical Name:: Octenidine dihydrochloride

Synonyms: Octenidine hydrochloride;SOT360;Octenidine DiHCl;Otinidine hydrochloride;ocenidine dihydrochloride;OCTENIDINE DIHYDROCHLORIDE;Ortinidine dihydrochloride;TRANS-2-NONENAL 18829-56-6;OctenidineDihydrochloride>Octenidine dihydrochloride 97%

CBNumber:: CB7879838

Molecular Formula:: C36H64Cl2N4

Molecular Weight:: 623.82616

MDL Number:: MFCD01938808

MOL File:: 70775-75-6.mol

Last updated:2024-12-20 13:16:41

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Octenidine dihydrochloride Properties

Melting point	215-217℃
Density	1.046[at 20℃]
vapor pressure	0Pa at 25℃
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Soluble in dimethyl sulfoxide and methanol.
form	Solid
color	White to Off-White
Water Solubility	14.2g/L at 20℃
Merck	14,6754
Stability	Hygroscopic
InChIKey	SMGTYJPMKXNQFY-UHFFFAOYSA-N
SMILES	[N+]1(CCCCCCCCCC[N+]2C=CC(NCCCCCCCC)=CC=2)=CC=C(NCCCCCCCC)C=C1.[Cl-].[Cl-]
LogP	1.5 at 23℃
FDA UNII	U84956NU4B

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302+H312+H332-H315-H319-H335

Precautionary statements

P280-P301+P312-P362+P364

HS Code

2933399990

NFPA 704

	1
2		0

Octenidine dihydrochloride price More Price(29)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	O0388	Octenidine Dihydrochloride >98.0%(HPLC)(N)	70775-75-6	1g	$29	2024-03-01	Buy
TCI Chemical	O0388	Octenidine Dihydrochloride >98.0%(HPLC)(N)	70775-75-6	5g	$114	2024-03-01	Buy
Alfa Aesar	H62257	Octenidine dihydrochloride, 98%	70775-75-6	1g	$34.9	2024-03-01	Buy
Alfa Aesar	H62257	Octenidine dihydrochloride, 98%	70775-75-6	5g	$137	2024-03-01	Buy
TRC	O239150	Octenidine Dihydrochloride	70775-75-6	5g	$120	2021-12-16	Buy

Product number	Packaging	Price	Buy
O0388	1g	$29	Buy
O0388	5g	$114	Buy
H62257	1g	$34.9	Buy
H62257	5g	$137	Buy
O239150	5g	$120	Buy

Octenidine dihydrochloride Chemical Properties,Uses,Production

Description

The antiseptic agent octenidine dihydrochloride (OCT) was developed by Sterling Winthrop (WIN41464-2) in the 1980s as an alternative to the anti-plaque agent CHX and successfully tested in vitro and in vivo. OCT has a broad spectrum of activity with similar effectiveness against Gram-negative and Gram-positive bacteria, fungi, and yeasts. Moreover, it has been shown that it may effectively interfere with the co-aggregation of dental plaque microbial colonizers without disturbing the normal, healthy oral flora. In a standardized comparison of antimicrobial activity ofthe antiseptic agents triclosan, polyvinylpyrrolidone-iodine, OCT, polyhexamethylene biguanide, and Chlorhexidine digluconat (CHX) using the min-imal effective concentration and minimum bactericidal con-centration, OCT was the most effective active agent of alltested antimicrobial substances. In other studies, the antibacterial and antiplaque efficacy of OCT was equal to or even greater than that of CHX[1].

Uses

Octenidine is an antiseptic (topical). Octenidine is a cationic surfactant and bis-(dihydropyridinyl)-decane derivative.

Uses

Octenidine dihydrochloride is used as a antiseptic for skin, mucous Membranes and wounds.

Application

Octenidine dihydrochloride is a cationic antiseptic that belongs to the bispyridine class of chemicals. Its action is binding to anionic structures of the cell membrane, further bursting the membrane. It has activity against Gram-positive and Gram-negative bacteria. It was effective in oral hygiene, preventing plaque and gingivitis, as a whole body wash for methicillin-resistant S. aureus decolonization and skin disinfection of premature newborn infants. Octenidine concentrations of less than 1.5 μM (0.94 μg/mL) reduced each microbial population by more than 99% within 15 minutes. Staphylococcus epidermidis was the most susceptible of the test organisms, and E. coli and Candida albicans were the least susceptible. Octenidine was more active than chlorhexidine against each test strain. This antiseptic has not been established in veterinary medicine for skin preparation but is used for wound cleansing.

Flammability and Explosibility

Not classified

References

[1] A. Welk. “Antibacterial and antiplaque efficacy of a commercially available octenidine-containing mouthrinse.” Clinical Oral Investigations 20 1 (2015): 1469–1476.

Octenidine dihydrochloride synthesis

Synthesis of Octenidine dihydrochloride from 1,10-Dichlorodecane and N-octylpyridin-4-amine

Octenidine dihydrochloride Preparation Products And Raw materials

Raw materials

OCTYLAMINE HYDROCHLORIDE N-octylpyridin-4-amine 1,10-Dichlorodecane 4-Aminopyridine

Preparation Products

Octenidine dihydrochloride Suppliers

Global( 277)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Jinan Jianfeng Chemical Co., Ltd	0531-88110457; +8615562555968	info@pharmachemm.com	China	251	58
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	5857	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5889	58
Hebei Weibang Biotechnology Co., Ltd	+8617732866630	bess@weibangbio.com	China	18150	58
Hebei Weimiao Import and Export Trade Co., Ltd.	+86-19948166995 +86-19948166995	sale01@hbweimiao.com	China	76	58
airuikechemical co., ltd.	+undefined86-15315557071	sales02@sdzhonghuimaterial.com	China	983	58
Hebei Saisier Technology Co., LTD	+86-18400010335 +86-18034520335	admin@hbsaisier.cn	China	1015	58
Hebei Longbang Technology Co., LTD	+86-18633929156 +86-18633929156	admin@hblongbang.com	China	941	58
Watson Biotechnology Co.,Ltd	+86-18186686046 +86-18186686046	sales01@watsonbiotech.cn	China	5841	58
Hebei Zhuanglai Chemical Trading Co Ltd	+86-16264648883 +86-16264648883	niki@zlchemi.com	China	2789	58

Supplier	Advantage
Jinan Jianfeng Chemical Co., Ltd	58
Hebei Yanxi Chemical Co., Ltd.	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Hebei Weibang Biotechnology Co., Ltd	58
Hebei Weimiao Import and Export Trade Co., Ltd.	58
airuikechemical co., ltd.	58
Hebei Saisier Technology Co., LTD	58
Hebei Longbang Technology Co., LTD	58
Watson Biotechnology Co.,Ltd	58
Hebei Zhuanglai Chemical Trading Co Ltd	58

View Lastest Price from Octenidine dihydrochloride manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-12-23	Octenidine dihydrochloride 70775-75-6	US $0.00-0.00 / kg	1kg	99%	20MT	Watson Biotechnology Co.,Ltd
2024-12-23	Octenidine dihydrochloride 70775-75-6	US $1.00 / kg	0.10000000kg	99%	200KG	Jinan Million Pharmaceutical Co., Ltd
2024-12-23	Octenidine dihydrochloride 70775-75-6	US $7.00 / g	5g	99%	20t	Jinan Jianfeng Chemical Co., Ltd

Octenidine dihydrochloride
70775-75-6
US $0.00-0.00 / kg
99%
Watson Biotechnology Co.,Ltd

Octenidine dihydrochloride
70775-75-6
US $1.00 / kg
99%
Jinan Million Pharmaceutical Co., Ltd

Octenidine dihydrochloride
70775-75-6
US $7.00 / g
99%
Jinan Jianfeng Chemical Co., Ltd

Octenidine dihydrochloride Spectrum

Octenidine dihydrochloride(70775-75-6)MS

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N,N'-(1,10-Decanediyldi-1(4H)-pyridinyl-4-ylidene)bis(1-octanamine) dihydrochloride N,N'-(decane-1,10-diyldi-1(4H)-pyridyl-4-ylidene)bis(octylammonium) dichloride OCTENIDINE DIHYDROCHLORIDE N,N'-(1,10-Decanediyldi-1(4H)-pyridinyl-4-ylidene)bis-1-octanaMine Hydrochloride N'-(decane-1,10-diyldi-1(4H)-pyridyl-4-ylidene)bis(octylaMMoniuM) dichloride 1-OctanaMine,N,N'-(1,10-decanediyldi-1(4H)-pyridinyl-4-ylidene)bis-, hydrochloride (1:2) ocenidine dihydrochloride -(decane-1,10-diyldi-1(4H)-pyridyl-4-ylidene)bis(octylammonium) dichloride Octenidine dihydrochloride 97% SOT360 Octenidine DiHCl OctenidineDihydrochloride> 1,1'-(Decane-1,10-diyl)bis(N-octylpyridin-4(1H)-imine) dihydrochloride N,N'-(1,1'-(decane-1,10-diyl)bis(pyridin-1(1H)-yl-4(1H)-ylidene))bis(octan-1-amine) dihydrochloride Octenidine dihydrochloride USP/EP/BP Octenidine Dihydrochloride DISCONTINUED, offer O239150 Pharmaceutical Intermediate Octenidine HCl/Octenidine Hydrochloride CAS 70775-75-6 N-octyl-1-[10-[4-(octylamino)pyridin-1-ium-1-yl]decyl]pyridin-1-ium-4-amine N,N'-(decane-1,10-diyldi-1(4H)-pyridyl-4-ylidene)bis(octylam... Octenidine dihydrochlorideQ: What is Octenidine dihydrochloride Q: What is the CAS Number of Octenidine dihydrochloride Q: What is the storage condition of Octenidine dihydrochloride TIANFUCHEM--70775-75-6--High purity N,N'-(decane-1,10-diyldi-1(4H)-pyridyl-4-ylidene)bis(octylammonium) dichloride factory price Octenidine hydrochloride Ortinidine dihydrochloride Otinidine hydrochloride TRANS-2-NONENAL 18829-56-6 Octenidine Dihydrochloride,98% Octenidine Dihydrochloride, ≥ 98.0% 1,1'-(Decane-1,10-diyl)bis(N-octylpyridin-4(1H)-imine) dihydrochloride N,N'-(decane-1,10-diyldi-1(4H)-pyridyl-4-ylidene)bis(octylammonium) dichloride N,N'-(1,10-Decanediyldi-1(4H)-pyridinyl-4-ylidene)bis-1-octanaMine Hydrochloride 70775-75-6 76775-75-6 C36H62N42HCl Amines Heterocycles Intermediates & Fine Chemicals Pharmaceuticals 70775-75-6 API