ChemicalBook >> CAS DataBase List >>2-Pyridinecarboxylic acid, 5-[10-(6-carboxy-3-pyridinyl)decyl]-, 2-methyl ester
2-Pyridinecarboxylic acid, 5-[10-(6-carboxy-3-pyridinyl)decyl]-, 2-methyl ester
- CAS No.
- 1418291-70-9
- Chemical Name:
- 2-Pyridinecarboxylic acid, 5-[10-(6-carboxy-3-pyridinyl)decyl]-, 2-methyl ester
- Synonyms
- Penicolinate B;2-Pyridinecarboxylic acid, 5-[10-(6-carboxy-3-pyridinyl)decyl]-, 2-methyl ester
- CBNumber:
- CB79018306
- Molecular Formula:
- C23H30N2O4
- Molecular Weight:
- 398.5
- MDL Number:
- MOL File:
- 1418291-70-9.mol
Last updated:2023-05-21 10:59:17
2-Pyridinecarboxylic acid, 5-[10-(6-carboxy-3-pyridinyl)decyl]-, 2-methyl ester Chemical Properties,Uses,Production
Biological Activity
Penicolinate B is a fungal metabolite originally isolated from Penicillium that has diverse biological activities.1 It is active against M. tuberculosis (MIC = 25 μg/ml), as well as P. falciparum, B. cereus, and C. albicans (IC50s = 1.4, 25, and 3.67 μg/ml, respectively). Penicolinate B is cytotoxic to MCF-7, KB, NCI H187, and Vero cells (IC50s = 6.21, 17.78, 0.307, and 2.79 μg/ml, respectively).
References
1.Intaraudom, C., Boonyuen, N., Suvannakad, R., et al.Penicolinates A-E from endophytic Penicillium sp. BCC16054Tetrahedron Lett.54(8)744-748(2013)
2-Pyridinecarboxylic acid, 5-[10-(6-carboxy-3-pyridinyl)decyl]-, 2-methyl ester Preparation Products And Raw materials
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2-Pyridinecarboxylic acid, 5-[10-(6-carboxy-3-pyridinyl)decyl]-, 2-methyl ester
Penicolinate B
1418291-70-9