Ethanesulfonyl fluoride, 1,1,2,2-tetrafluoro-2-(phenylthio)-
- CAS No.
- 1000294-01-8
- Chemical Name:
- Ethanesulfonyl fluoride, 1,1,2,2-tetrafluoro-2-(phenylthio)-
- Synonyms
- 1,1,2,2-Tetrafluoro-2-(phenylthio)ethane-1-sulfonyl fluoride;1,1,2,2-tetrafluoro-2-(phenylsulfanyl)ethanesulfonylfluoride;Ethanesulfonyl fluoride, 1,1,2,2-tetrafluoro-2-(phenylthio)-
- CBNumber:
- CB79022286
- Molecular Formula:
- C8H5F5O2S2
- Molecular Weight:
- 292.25
- MDL Number:
- MFCD31922992
- MOL File:
- 1000294-01-8.mol
Last updated:2022-08-15 17:39:23
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS05 |
---|---|
Signal word | Danger |
Hazard statements | H314 |
Precautionary statements | P280-P301+P330+P331-P303+P361+P353-P305+P351+P338+P310 |
Ethanesulfonyl fluoride, 1,1,2,2-tetrafluoro-2-(phenylthio)- Chemical Properties,Uses,Production
Uses
Phenylsulfanyltetrafluoroethanesulfonyl fluoride serves as a moderately reactive phenylsulfanyltetrafluoroethanesulfonylation reagent. A phenylsulfanyltetrafluoroethyl moiety incorporated in the substrate can be treated with tributyltin hydride and generate the corresponding fluoroalkyl radical which can add to neighbouring olefins, creating tetrafluorinated carbocycles. If the substrate lacks any olefins, it can be reduced to a tetrafluoroethyl group. Generally, fluoroalkylsulfonylation of the amine nitrogen greatly lowers the pKa value of the N-H and can be used to modulate the behaviour of the drug candidate or build additional molecular complexity around the highly acidic fluoroalkylsulfonamide nitrogen.
Ethanesulfonyl fluoride, 1,1,2,2-tetrafluoro-2-(phenylthio)- Preparation Products And Raw materials
Raw materials
Preparation Products
Ethanesulfonyl fluoride, 1,1,2,2-tetrafluoro-2-(phenylthio)- Suppliers
Global( 2)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Dalian Shuanghang Chemical Co., LTD | 411-66858498 165240430 | sales@dl-bykj.cn | China | 1987 | 58 |
TCI (Shanghai) Chemical Trading Co., Ltd. | 021-021-61109150 | sales@tcisct.com | China | 31130 | 58 |
Supplier | Advantage |
---|---|
Dalian Shuanghang Chemical Co., LTD | 58 |
TCI (Shanghai) Chemical Trading Co., Ltd. | 58 |
Ethanesulfonyl fluoride, 1,1,2,2-tetrafluoro-2-(phenylthio)-
1,1,2,2-tetrafluoro-2-(phenylsulfanyl)ethanesulfonylfluoride
1,1,2,2-Tetrafluoro-2-(phenylthio)ethane-1-sulfonyl fluoride
1000294-01-8
C8H5F5O2S2