ChemicalBook >> CAS DataBase List >>(3S,6R,7S,8S,12Z,15S,16E)-1,3,15-TRIS-{[TERT-BUTYL(DIMETHYL)SILYL]OXY}-7-HYDROXY-4,4,6,8,12,16-HEXAMETHYL-17-(2-METHYL-1,3-THIAZOL-4-YL)HEPTADECYL-12,16-DIEN-5-ONE
(3S,6R,7S,8S,12Z,15S,16E)-1,3,15-TRIS-{[TERT-BUTYL(DIMETHYL)SILYL]OXY}-7-HYDROXY-4,4,6,8,12,16-HEXAMETHYL-17-(2-METHYL-1,3-THIAZOL-4-YL)HEPTADECYL-12,16-DIEN-5-ONE
![(3S,6R,7S,8S,12Z,15S,16E)-1,3,15-TRIS-{[TERT-BUTYL(DIMETHYL)SILYL]OXY}-7-HYDROXY-4,4,6,8,12,16-HEXAMETHYL-17-(2-METHYL-1,3-THIAZOL-4-YL)HEPTADECYL-12,16-DIEN-5-ONE Structure](StructureFile/ChemBookStructure22/GIF/CB7973163.gif)
- CAS No.
- 193146-49-5
- Chemical Name:
- (3S,6R,7S,8S,12Z,15S,16E)-1,3,15-TRIS-{[TERT-BUTYL(DIMETHYL)SILYL]OXY}-7-HYDROXY-4,4,6,8,12,16-HEXAMETHYL-17-(2-METHYL-1,3-THIAZOL-4-YL)HEPTADECYL-12,16-DIEN-5-ONE
- Synonyms
- (3S,6R,7S,8S,12Z,15S,16E)-1,3,15-tris[[tert-butyl(dimethyl)silyl]oxy]-7-hydroxy-4,4,6,8,12,16-hexamethyl-17-(2-methyl-1,3-thiazol-4-yl)heptadeca-12,16-dien-5-one;(3S,6R,7S,8S,12Z,15S,16E)-1,3,15-TRIS-{[TERT-BUTYL(DIMETHYL)SILYL]OXY}-7-HYDROXY-4,4,6,8,12,16-HEXAMETHYL-17-(2-METHYL-1,3-THIAZOL-4-YL)HEPTADECYL-12,16-DIEN-5-ONE;12,16-Heptadecadien-5-one, 1,3,15-tris[[(1,1-dimethylethyl)dimethylsilyl]oxy]-7-hydroxy-4,4,6,8,12,16-hexamethyl-17-(2-methyl-4-thiazolyl)-, (3S,6R,7S,8S,12Z,15S,16E)-
- CBNumber:
- CB7973163
- Molecular Formula:
- C45H87NO5SSi3
- Molecular Weight:
- 838.5
- MDL Number:
- MFCD04039708
- MOL File:
- Mol file
Last updated:2023-04-23 13:52:06
(3S,6R,7S,8S,12Z,15S,16E)-1,3,15-TRIS-{[TERT-BUTYL(DIMETHYL)SILYL]OXY}-7-HYDROXY-4,4,6,8,12,16-HEXAMETHYL-17-(2-METHYL-1,3-THIAZOL-4-YL)HEPTADECYL-12,16-DIEN-5-ONE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | T876675 | (3S,6R,7S,8S,12Z,15S,16E)-1,3,15-Tris-{[tert-butyl(dimethyl)silyl]oxy}-7-hydroxy-4,4,6,8,12,16-hexamethyl-17-(2-methyl-1,3-thiazol-4-yl)heptadecyl-12,16-dien-5-one | 193146-49-5 | 0.5mg | $140 | 2021-12-16 | Buy |
| Product number | Packaging | Price | Buy |
|---|---|---|---|
| T876675 | 0.5mg | $140 | Buy |
(3S,6R,7S,8S,12Z,15S,16E)-1,3,15-TRIS-{[TERT-BUTYL(DIMETHYL)SILYL]OXY}-7-HYDROXY-4,4,6,8,12,16-HEXAMETHYL-17-(2-METHYL-1,3-THIAZOL-4-YL)HEPTADECYL-12,16-DIEN-5-ONE Chemical Properties,Uses,Production
Chemical Properties
Colourless Oil
Uses
An intermediate in the synthesis of Epothilones. Epothilones are polyketide natural products that inhibit cancer cells by a mechanism similar to paclitaxel, and also are effective against paclitaxel-resistant tumours. Epothilone D is in phase I clinical testing of in patients with advanced solid tumours. Epothilone D is a cytotoxic macrolide that stabilises malignant cells'' microtubules and arrests mitosis, a characteristic it shares with other epothilones. They bind to the same hepatic sites as does paclitaxel (Taxol) in a 1:1 stoichiometric ratio of a, b-tubulin heterodimers.
(3S,6R,7S,8S,12Z,15S,16E)-1,3,15-TRIS-{[TERT-BUTYL(DIMETHYL)SILYL]OXY}-7-HYDROXY-4,4,6,8,12,16-HEXAMETHYL-17-(2-METHYL-1,3-THIAZOL-4-YL)HEPTADECYL-12,16-DIEN-5-ONE Preparation Products And Raw materials
Raw materials
Preparation Products
(3S,6R,7S,8S,12Z,15S,16E)-1,3,15-TRIS-{[TERT-BUTYL(DIMETHYL)SILYL]OXY}-7-HYDROXY-4,4,6,8,12,16-HEXAMETHYL-17-(2-METHYL-1,3-THIAZOL-4-YL)HEPTADECYL-12,16-DIEN-5-ONE Suppliers
Global( 9)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94658 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 | sales@rrkchem.com | China | 56077 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44843 | 58 |
(3S,6R,7S,8S,12Z,15S,16E)-1,3,15-TRIS-{[TERT-BUTYL(DIMETHYL)SILYL]OXY}-7-HYDROXY-4,4,6,8,12,16-HEXAMETHYL-17-(2-METHYL-1,3-THIAZOL-4-YL)HEPTADECYL-12,16-DIEN-5-ONE
(3S,6R,7S,8S,12Z,15S,16E)-1,3,15-tris[[tert-butyl(dimethyl)silyl]oxy]-7-hydroxy-4,4,6,8,12,16-hexamethyl-17-(2-methyl-1,3-thiazol-4-yl)heptadeca-12,16-dien-5-one
12,16-Heptadecadien-5-one, 1,3,15-tris[[(1,1-dimethylethyl)dimethylsilyl]oxy]-7-hydroxy-4,4,6,8,12,16-hexamethyl-17-(2-methyl-4-thiazolyl)-, (3S,6R,7S,8S,12Z,15S,16E)-
193146-49-5
Chiral Reagents