BRAF V600E/CRAF-IN-2
- CAS No.
- 2499499-62-4
- Chemical Name:
- BRAF V600E/CRAF-IN-2
- Synonyms
- BRAF V600E/CRAF-IN-2
- CBNumber:
- CB811557940
- Molecular Formula:
- C30H30F3N5O2
- Molecular Weight:
- 549.6
- MDL Number:
- MOL File:
- 2499499-62-4.mol
BRAF V600E/CRAF-IN-2 Chemical Properties,Uses,Production
Uses
BRAF V600E/CRAF-IN-2 (Compound 9c) is a potent inhibitor of BRAF V600E/CRAF with IC50s of 0.888 and 0.229 μM, respectively. BRAF V600E/CRAF-IN-2 triggers apoptosis and cell cycle arrest at G0/G1 phase in HCT-116 colon cancer cell. BRAF V600E/CRAF-IN-2 has the potential for the research of cancer diseases[1].
References
[1] El-Damasy AK,et al. 2-Anilinoquinoline based arylamides as broad spectrum anticancer agents with B-RAFV600E/C-RAF kinase inhibitory effects: Design, synthesis, in vitro cell-based and oncogenic kinase assessments. Eur J Med Chem. 2020 Dec 15;208:112756. DOI:10.1016/j.ejmech.2020.112756
BRAF V600E/CRAF-IN-2 Preparation Products And Raw materials
Raw materials
Preparation Products
BRAF V600E/CRAF-IN-2 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19881 | 58 |
| Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd | 15317229551 | 15151849396@163.com | China | 998 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19710 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd | 58 |
| TargetMol Chemicals Inc. | 58 |
View Lastest Price from BRAF V600E/CRAF-IN-2 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-24 | BRAF V600E/CRAF-IN-2
2499499-62-4
|
US $1980.00-1520.00 / mg | 10g | TargetMol Chemicals Inc. |
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- BRAF V600E/CRAF-IN-2
2499499-62-4
- US $1980.00-1520.00 / mg
- TargetMol Chemicals Inc.