4-methylquinoline
- CAS No.
- 491-35-0
- Chemical Name:
- 4-methylquinoline
- Synonyms
- 4-METHYLQUINOLINE;4-Lepidine;4-METHYLCHINOLINE;Lepidin;epidine;LEPIDINE;Lepidine>Lepidine,98%;Lepidine ,99%;4-Methylchinol
- CBNumber:
- CB8121295
- Molecular Formula:
- C10H9N
- Molecular Weight:
- 143.19
- MDL Number:
- MFCD00006784
- MOL File:
- 491-35-0.mol
- MSDS File:
- SDS
| Melting point | 9-10 °C(lit.) |
|---|---|
| Boiling point | 261-263 °C(lit.) |
| Density | 1.083 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Refrigerator |
| solubility | Slightly soluble in water, miscible with alcohol and oils. |
| pka | 5.67(at 20℃) |
| form | Liquid |
| color | Pale Orange |
| Odor | at 100.00 %. burnt oily herbal floral sweet |
| Odor Type | burnt |
| Water Solubility | Slightly soluble |
| Sensitive | Light Sensitive |
| Merck | 14,5441 |
| BRN | 110926 |
| InChIKey | MUDSDYNRBDKLGK-UHFFFAOYSA-N |
| LogP | 2.610 |
| CAS DataBase Reference | 491-35-0(CAS DataBase Reference) |
| Substances Added to Food (formerly EAFUS) | LEPIDINE |
| EWG's Food Scores | 2 |
| FDA UNII | 116169T3O8 |
| NIST Chemistry Reference | Quinoline, 4-methyl-(491-35-0) |
| EPA Substance Registry System | Quinoline, 4-methyl- (491-35-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-68-40 | |||||||||
| Safety Statements | 26-36-45-36/37/39-22 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | OH0316000 | |||||||||
| F | 8-10 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29334900 | |||||||||
| Hazardous Substances Data | 491-35-0(Hazardous Substances Data) | |||||||||
| NFPA 704 |
|
4-methylquinoline price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 158283 | Lepidine 99% | 491-35-0 | 25g | $99.3 | 2024-03-01 | Buy |
| Sigma-Aldrich | 158283 | Lepidine 99% | 491-35-0 | 100g | $188 | 2024-03-01 | Buy |
| TCI Chemical | L0024 | Lepidine >97.0%(GC)(T) | 491-35-0 | 25mL | $59 | 2024-03-01 | Buy |
| TCI Chemical | L0024 | Lepidine >97.0%(GC)(T) | 491-35-0 | 100mL | $165 | 2024-03-01 | Buy |
| Alfa Aesar | A14040 | Lepidine, 97% | 491-35-0 | 10g | $45.65 | 2024-03-01 | Buy |
4-methylquinoline Chemical Properties,Uses,Production
Description
Refer to 6-METHYLQUINOLINE.
Chemical Properties
clear slightly yellow to brown liquid
Physical properties
4-Methylquinoline is a colorless liquid with a weak quinoline-like odor. It is slightly soluble in water, miscible with many organic solvents, and volatile in steam.
Uses
4-Methylquinoline is used as a reagent in the synthesis of azetidine based ene-amides as potent bacterial enoyl ACP reductase inhibitors. Also used as a reagent in the synthesis of cyanine-styryl dyes with enhanced photostability for fluorescent DNA imaging.
Uses
4-methylquinoline is used mainly in flavor compositions for imitation Honey, Nut, Butter, Caramel, etc. and in certain fruit complexes. The concentration used is normally about 0.2 to 2 ppm in the finished product.
Definition
ChEBI: A methylquinoline carrying a methyl substituent at position 4.
Production Methods
4-Methylquinoline can be recovered from the highest-boiling fraction of the coal-tar quinoline bases via its o-cresol addition compound. It can be synthesized by condensation of aniline and methyl vinyl ketone.
Synthesis Reference(s)
Tetrahedron Letters, 28, p. 5291, 1987 DOI: 10.1016/S0040-4039(00)96710-8
General Description
Synthesis of lepidine from 4-anilinobutan-2-one in ethanol in the presence of HCl or FeCl3 has been reported. Nitration of lepidine has been reported.
Purification Methods
Reflux lepidine with BaO, then fractionally distil it. Further purify it via its recrystallised dichromate salt (m 138o) (from H2O). [Cumper et al. J Chem Soc 1176 1962.] [Beilstein 20 III/IV 3477, 20/7 V 389.]
4-methylquinoline Preparation Products And Raw materials
Raw materials
1of4
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8808 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12834 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29880 | 58 |
| Shanghai Arbor Chemical Co., Ltd. | 021-60451682 | act@arborchemical.com | CHINA | 904 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8618959220845 | sales@amoychem.com | China | 6383 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
View Lastest Price from 4-methylquinoline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-12-13 | 4-Methylquinoline
491-35-0
|
US $0.00 / KG | 1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2024-11-13 | Lepidine
491-35-0
|
US $10.00 / kg | 1kg | 99% | 100 mt | Hebei Weibang Biotechnology Co., Ltd | |
 |
2023-08-26 | 4-methylquinoline
491-35-0
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd |
-
- 4-Methylquinoline
491-35-0
- US $0.00 / KG
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Lepidine
491-35-0
- US $10.00 / kg
- 99%
- Hebei Weibang Biotechnology Co., Ltd
-
- 4-methylquinoline
491-35-0
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd