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ChemicalBook >> CAS DataBase List >>3-Pyridinecarboxamide, 5-[2-(acetylamino)imidazo[1,2-b]pyridazin-6-yl]-N-[[2-(cyclopropylmethoxy)-3,5-difluorophenyl]methyl]-6-methyl-

3-Pyridinecarboxamide, 5-[2-(acetylamino)imidazo[1,2-b]pyridazin-6-yl]-N-[[2-(cyclopropylmethoxy)-3,5-difluorophenyl]methyl]-6-methyl-

3-Pyridinecarboxamide, 5-[2-(acetylamino)imidazo[1,2-b]pyridazin-6-yl]-N-[[2-(cyclopropylmethoxy)-3,5-difluorophenyl]methyl]-6-methyl- Structure
3-Pyridinecarboxamide, 5-[2-(acetylamino)imidazo[1,2-b]pyridazin-6-yl]-N-[[2-(cyclopropylmethoxy)-3,5-difluorophenyl]methyl]-6-methyl- structure
CAS No.
2319663-07-3
Chemical Name:
3-Pyridinecarboxamide, 5-[2-(acetylamino)imidazo[1,2-b]pyridazin-6-yl]-N-[[2-(cyclopropylmethoxy)-3,5-difluorophenyl]methyl]-6-methyl-
Synonyms
RIPK1-IN-8;3-Pyridinecarboxamide, 5-[2-(acetylamino)imidazo[1,2-b]pyridazin-6-yl]-N-[[2-(cyclopropylmethoxy)-3,5-difluorophenyl]methyl]-6-methyl-
CBNumber:
CB812594522
Molecular Formula:
C26H24F2N6O3
Molecular Weight:
506.5
MDL Number:
MOL File:
2319663-07-3.mol
Last updated:2025-04-17 18:22:24
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3-Pyridinecarboxamide, 5-[2-(acetylamino)imidazo[1,2-b]pyridazin-6-yl]-N-[[2-(cyclopropylmethoxy)-3,5-difluorophenyl]methyl]-6-methyl- Properties

Density 1.45±0.1 g/cm3(Predicted)
pka 9.60±0.46(Predicted)

3-Pyridinecarboxamide, 5-[2-(acetylamino)imidazo[1,2-b]pyridazin-6-yl]-N-[[2-(cyclopropylmethoxy)-3,5-difluorophenyl]methyl]-6-methyl- Chemical Properties,Uses,Production

Uses

RIPK1-IN-8 (example 16), an aminoimidazopyridine, is a potent and selective RIPK1 inhibitor with an IC50 of 4 nM. RIPK1-IN-8 has the potential for inflammatory diseases research[1].

IC 50

RIPK1

References

[1] Michael E. Mertzman, et al. Aminoimidazopyridines as kinase inhibitors. WO2019089442A1.

3-Pyridinecarboxamide, 5-[2-(acetylamino)imidazo[1,2-b]pyridazin-6-yl]-N-[[2-(cyclopropylmethoxy)-3,5-difluorophenyl]methyl]-6-methyl- Preparation Products And Raw materials

Raw materials

Preparation Products

3-Pyridinecarboxamide, 5-[2-(acetylamino)imidazo[1,2-b]pyridazin-6-yl]-N-[[2-(cyclopropylmethoxy)-3,5-difluorophenyl]methyl]-6-methyl- Suppliers

Global( 2)Suppliers
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TargetMol Chemicals Inc. 		+8613564774135 zijue.cai@tsbiochem.com United States 19881 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19699 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
TargetMol Chemicals Inc. 58

View Lastest Price from 3-Pyridinecarboxamide, 5-[2-(acetylamino)imidazo[1,2-b]pyridazin-6-yl]-N-[[2-(cyclopropylmethoxy)-3,5-difluorophenyl]methyl]-6-methyl- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
RIPK1-IN-8 pictures 2024-11-19 RIPK1-IN-8
2319663-07-3
 US $2500.00-1520.00 / mg 10g TargetMol Chemicals Inc.
  • RIPK1-IN-8 pictures
  • RIPK1-IN-8
    2319663-07-3
  • US $2500.00-1520.00 / mg
  • TargetMol Chemicals Inc.
3-Pyridinecarboxamide, 5-[2-(acetylamino)imidazo[1,2-b]pyridazin-6-yl]-N-[[2-(cyclopropylmethoxy)-3,5-difluorophenyl]methyl]-6-methyl- RIPK1-IN-8 2319663-07-3