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ChemicalBook >> CAS DataBase List >>4-Thiazolidinone, 3-(3-methylphenyl)-2-[3-(2-oxo-2H-1-benzopyran-3-yl)-1-phenyl-1H-pyrazol-4-yl]-

4-Thiazolidinone, 3-(3-methylphenyl)-2-[3-(2-oxo-2H-1-benzopyran-3-yl)-1-phenyl-1H-pyrazol-4-yl]-

4-Thiazolidinone, 3-(3-methylphenyl)-2-[3-(2-oxo-2H-1-benzopyran-3-yl)-1-phenyl-1H-pyrazol-4-yl]- Structure
4-Thiazolidinone, 3-(3-methylphenyl)-2-[3-(2-oxo-2H-1-benzopyran-3-yl)-1-phenyl-1H-pyrazol-4-yl]- structure
CAS No.
2497504-72-8
Chemical Name:
4-Thiazolidinone, 3-(3-methylphenyl)-2-[3-(2-oxo-2H-1-benzopyran-3-yl)-1-phenyl-1H-pyrazol-4-yl]-
Synonyms
hCAIX-IN-10;4-Thiazolidinone, 3-(3-methylphenyl)-2-[3-(2-oxo-2H-1-benzopyran-3-yl)-1-phenyl-1H-pyrazol-4-yl]-
CBNumber:
CB812740608
Molecular Formula:
C28H21N3O3S
Molecular Weight:
479.55
MDL Number:
MOL File:
2497504-72-8.mol
Last updated:2025-04-18 09:52:49
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4-Thiazolidinone, 3-(3-methylphenyl)-2-[3-(2-oxo-2H-1-benzopyran-3-yl)-1-phenyl-1H-pyrazol-4-yl]- Properties

Boiling point 803.0±65.0 °C(Predicted)
Density 1.35±0.1 g/cm3(Predicted)
pka -1.12±0.40(Predicted)

4-Thiazolidinone, 3-(3-methylphenyl)-2-[3-(2-oxo-2H-1-benzopyran-3-yl)-1-phenyl-1H-pyrazol-4-yl]- Chemical Properties,Uses,Production

Uses

hCAIX-IN-10 (Compound 6i) is a selective carbonic anhydrase IX and XII inhibitor with Ki s of 61.5 and 586.8 nM for hCA IX and hCA XII, respectively. ?hCA IX and hCA XII are transmembrane isoforms which have been characterized as biomarkers for several types of tumors. The hCA XII assists in maintenance of acid-base homoeostasis in normal as well as tumor cells[1].

IC 50

CA Ⅸ

References

[1] Pavitra S Thacker,et al. Synthesis and biological evaluation of some coumarin hybrids as selective carbonic anhydrase IX and XII inhibitors. Bioorg Chem.?2020 Nov;104:104272. DOI:10.1016/j.bioorg.2020.104272

4-Thiazolidinone, 3-(3-methylphenyl)-2-[3-(2-oxo-2H-1-benzopyran-3-yl)-1-phenyl-1H-pyrazol-4-yl]- Preparation Products And Raw materials

Raw materials

Preparation Products

4-Thiazolidinone, 3-(3-methylphenyl)-2-[3-(2-oxo-2H-1-benzopyran-3-yl)-1-phenyl-1H-pyrazol-4-yl]- Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+8613564774135 zijue.cai@tsbiochem.com United States 19881 58
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 6345 55
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19727 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Tianjin Kailiqi Biotechnology Co., Ltd. 55
TargetMol Chemicals Inc. 58

View Lastest Price from 4-Thiazolidinone, 3-(3-methylphenyl)-2-[3-(2-oxo-2H-1-benzopyran-3-yl)-1-phenyl-1H-pyrazol-4-yl]- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
hCAIX-IN-10 pictures 2024-10-28 hCAIX-IN-10
2497504-72-8
 US $3520.00-2140.00 / mg 10g TargetMol Chemicals Inc.
  • hCAIX-IN-10 pictures
  • hCAIX-IN-10
    2497504-72-8
  • US $3520.00-2140.00 / mg
  • TargetMol Chemicals Inc.
4-Thiazolidinone, 3-(3-methylphenyl)-2-[3-(2-oxo-2H-1-benzopyran-3-yl)-1-phenyl-1H-pyrazol-4-yl]- hCAIX-IN-10 2497504-72-8