Estrogens
- CAS No.
- Chemical Name:
- Estrogens
- Synonyms
- Estrogens
- CBNumber:
- CB81318522
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Estrogens Chemical Properties,Uses,Production
Uses
Estrogens, estrone (28.1.9), estradiol (28.1.17), ethynylestradiol (28.1.26), diethylstilbestrol (28.1.33), and chlorotrianisene (30.5.2), are used for palliative treatment of post-menopausal breast cancer, prostate cancer, and breast cancer in men. It is highly probable that the mechanism of action is similar to the mechanism of action of androgens. 
World Health Organization (WHO)
Preparations containing both an estrogen and a progestogen in fixed combination were introduced for oral contraception in 1960. In late 1960's, use of products containing more than 50 mcg of estrogen was demonstrated to be associated with an increased risk of thrombo-embolic disease. Such formulations, which offer no advantage in terms of efficacy have subsequently been largely abandoned.
World Health Organization (WHO)
Estrogens have been used for the prevention of postpartum breast pain and engorgement. However, because of an increased risk of puerperal thromboembolism and a risk of rebound effect, and since only 10% of women benefit therapeutically from such intervention, the United States Food and Drug Administration has requested manufacturers to no longer indicate preparations containing estrogens for this purpose. The World Health Organization is not aware of similar action having been taken elsewhere.