thalistyline
- CAS No.
- 62251-53-0
- Chemical Name:
- thalistyline
- Synonyms
- thalistyline;(1S)-1,2,3,4-Tetrahydro-5,6,7-trimethoxy-1-[[4-methoxy-3-[4-[[(5S)-5,6,7,8-tetrahydro-9-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]methyl]phenoxy]phenyl]methyl]-2,2-dimethylisoquinolin-2-ium
- CBNumber:
- CB81364903
- Molecular Formula:
- C41H49N2O8
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- 62251-53-0.mol
thalistyline Chemical Properties,Uses,Production
Description
A quaternary bisbenzylisoquinoline alkaloid, thalistyline has been isolated from Thalictrum longistylum DC and T. podocarpum Hunb. grown in Columbia, South America. The base has been isolated as the chloride which forms needles from H20 with m.p. ISO-3°C and a specific rotation of [α]20D + 146° (c 0.1, MeOH). The ultraviolet spectrum of this salt has absorption maxima at 276 and 283 nm. The base has also been characterized as the crystalline iodide, m.p. 220-3°C (dec.) and methiodide, m.p. 266-8°C (dec.). Sodium-liquid ammonia cleavage gives an optically inactive phenolic base, C22H31NO4 as an oil and a phenolic base C18H21NO3 as colourless crystals, m.p. 221-2°C.
References
Wu, Beal, Doskotch, Tetrahedron Lett., 3687 (1976)
thalistyline Preparation Products And Raw materials
Raw materials
Preparation Products
thalistyline
(1S)-1,2,3,4-Tetrahydro-5,6,7-trimethoxy-1-[[4-methoxy-3-[4-[[(5S)-5,6,7,8-tetrahydro-9-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]methyl]phenoxy]phenyl]methyl]-2,2-dimethylisoquinolin-2-ium
62251-53-0
C41H49N2O8