ChemicalBook >> CAS DataBase List >>LUPULONE
LUPULONE
- CAS No.
- 468-28-0
- Chemical Name:
- LUPULONE
- Synonyms
- lupulon;b’’-acid;LUPULONE;B-LUPULIC ACID;lohexadien-1-one;BETA-BITTER ACID;BETA-LUPULIC ACID;Lupulone beta-acid;Coclaurine Impurity 3;1-Amino-8-naphthol-3,5-disulfonic acid
- CBNumber:
- CB8136556
- Molecular Formula:
- C26H38O4
- Molecular Weight:
- 414.58
- MDL Number:
- MFCD00075970
- MOL File:
- 468-28-0.mol
- MSDS File:
- SDS
Last updated:2023-05-21 10:59:17
Melting point | 93℃ |
---|---|
Boiling point | 453.43°C (rough estimate) |
Density | 1.045±0.06 g/cm3 (20 ºC 760 Torr) |
vapor pressure | 0Pa at 20℃ |
refractive index | 1.4840 (estimate) |
storage temp. | Store at -20°C |
solubility | Methanol: slightly soluble |
form | A solid |
pka | 4.50±1.00(Predicted) |
Water Solubility | 1g/L at 20℃ |
Stability | Hygroscopic |
LogP | 4.5 at 20℃ |
EWG's Food Scores | 1 |
FDA UNII | B7425USG94 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H312-H302-H319-H317 |
Precautionary statements | P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P280-P302+P352-P312-P322-P363-P501-P264-P280-P305+P351+P338-P337+P313P-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501 |
Hazard Codes | T |
Risk Statements | 25 |
Safety Statements | 45 |
RIDADR | 2811 |
RTECS | OK5950000 |
HazardClass | 6.1(b) |
PackingGroup | III |
Toxicity | LD50 in mice, rats (mg/kg): 525, 100 orally (Hnsel, Wagener) |
LUPULONE price More Price(13)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 28481 | Lupulone | 468-28-0 | 1mg | $44 | 2024-03-01 | Buy |
Cayman Chemical | 28481 | Lupulone | 468-28-0 | 10mg | $384 | 2024-03-01 | Buy |
Cayman Chemical | 28481 | Lupulone | 468-28-0 | 5mg | $202 | 2024-03-01 | Buy |
TRC | L478000 | Lupulone | 468-28-0 | 10mg | $185 | 2021-12-16 | Buy |
Biosynth Carbosynth | FL74820 | Lupulone | 468-28-0 | 10mg | $300 | 2021-12-16 | Buy |
LUPULONE Chemical Properties,Uses,Production
Uses
Lupulone is a hop plant (Humulus lupulus L.) acid that inhibits tumorigenicity of hepatocellular carcinoma cells.
Definition
ChEBI: Lupulone is a beta-bitter acid in which the acyl group is specified as 3-methylbutanoyl. It has a role as an antimicrobial agent, an apoptosis inducer, an angiogenesis inhibitor and an antineoplastic agent. It is a conjugate acid of a lupulone(1-).
Purification Methods
Crystallise Lupulon from 90% MeOH, hexane or pet ether at low temperature. It has also been purified by chromatography through Kieselgel. [Wieland et al. Chem Ber 102 2012 1925, Riedl Chem Ber 85 692 1952, Beilstein 7 II 856, 7 III 4752, 7 IV 2866.]
LUPULONE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 64)Suppliers
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2,4-cyclohexadien-1-one,3,5-dihydroxy-4-isovaleryl-2,6,6-tris(3-methyl-2-but
3,5-dihydroxy-2,6,6-tris(3-methyl-2-butenyl)-4-(3-methyl-1-oxobutyl)-2,4-cyc
b’’-acid
lohexadien-1-one
lupulon
LUPULONE
B-LUPULIC ACID
BETA-LUPULIC ACID
BETA-BITTER ACID
3,5-DIHYDROXY-2,6,6-TRIS(3-METHYL-2-BUTENYL)-4-(3-METHYLBUTYRYL)-2,4-CYCLOHEXADIENONE
Lupulone beta-acid
3,5-dihydroxy-2,6,6-tris(3-methylbut-2-enyl)-4-(3-methyl-1-oxobutyl)cyclohexa-2,4-dien-1-one
3,5-dihydroxy-2,6,6-tris(3-methylbuten-2-yl)-4-(3-methyl-1-oxobutyl)cyclohexa-2,4-dien-1-one
1-Amino-8-naphthol-3,5-disulfonic acid
5-Amino-4-hydroxy-1,7-naphthalenedisulfonic acid
β-Bitter acid, β-Lupulic acid, 3,5-Dihydroxy-2,6,6-tris(3-methyl-2-butenyl)-4-(3-methylbutyryl)-2,4-cyclohexadienone
3,5-Dihydroxy-2,6,6-tris(3-methyl-2-butenyl)-4-(3-methyl-1-oxobutyl)-2,4-cyclohexadien-1-one
3,5-dihydroxy-2-(3-methylbutanoyl)-4,6,6-tris(3-methylbut-2-enyl)cyclohexa-2,4-dien-1-one
3,5-dihydroxy-2-isovaleryl-4,6,6-tris(3-methylbut-2-enyl)cyclohexa-2,4-dien-1-one
3,5-DIHYDROXY-2-(3-METHYLBUTANOYL)-4,6,6-TRIS(3-METHYLBUT-2-ENYL)CYCLOHE
2,4-Cyclohexadien-1-one,3,5-dihydroxy-2,6,6-tris(3-methyl-2-buten-1-yl)-4-(3-methyl-1-oxobutyl)-
Coclaurine Impurity 3
468-28-0
Analytical Chromatography Product Catalog
Alphabetic
Analytical Standards
Hop Compounds