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UCB 35625

CAS No.
202796-42-7
Chemical Name:
UCB 35625
Synonyms
trans-J-113863
CBNumber:
CB813754871
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
Last updated:2025-01-27 09:38:02

UCB 35625 Properties

storage temp. 2-8°C
solubility DMSO: 2mg/mL, clear
form powder
color white to beige
UNSPSC Code 12352200
NACRES NA.77

UCB 35625 Chemical Properties,Uses,Production

Biological Activity

UCB35625 is a high affinity antagonist for CCR1 and CCR3 receptors. Also both UCB35625 and its enantiomer J113863 exhibit low binding affinity toward CCR2 and CCR5 where they activate three Gi and two G0 protein isoforms. UCB35625 does not activate G12 protein isoform. J113863 binding to CCR2 and CCR5 induce the recruitment of b-arrestin 2 whereas UCB35625 did not. J113863 and UCB35625 are biased ligands for the chemokine receptors CCR2 and CCR5.

UCB 35625 Preparation Products And Raw materials

Raw materials

Preparation Products

UCB 35625 Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52924 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 5100 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19699 58
R&D Systems, Inc 18003437475 rdname@qq.com CHINA 35705 58
trans-J-113863 202796-42-7