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PPARγ-IN-2

CAS No.
2682078-97-1
Chemical Name:
PPARγ-IN-2
Synonyms
PPARγ-IN-2;1H-Indole-3-carboxaldehyde, 2-[4-[[2-(1-pyrrolidinyl)ethyl]amino]-2-pyrimidinyl]-
CBNumber:
CB814133804
Molecular Formula:
C19H21N5O
Molecular Weight:
335.4
MDL Number:
MOL File:
2682078-97-1.mol
Last updated:2025-04-18 09:52:49

PPARγ-IN-2 Properties

Boiling point 541.3±50.0 °C(predicted)
Density 1.304±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka 13.30±0.30(predicted)
form Solid
color Light yellow to yellow

PPARγ-IN-2 Chemical Properties,Uses,Production

Uses

PPARγ-IN-2 (Compound 5a) is a PPARγ inhibitor. PPARγ-IN-2 inhibits TG accumulation in 3T3-L1 preadipocytes (EC50: 0.106 μM). PPARγ-IN-2 inhibits high-cholesterol diet (HFC)-induced obesity and related metabolic syndrome, and reduces lipid accumulation in adipose tissue[1].

IC 50

PPARγ

References

[1] Guo SY, et al. Design, synthesis and evaluation of 2-pyrimidinylindole derivatives as anti-obesity agents by regulating lipid metabolism. Eur J Med Chem. 2023 Nov 15;260:115729. DOI:10.1016/j.ejmech.2023.115729

PPARγ-IN-2 Preparation Products And Raw materials

Raw materials

Preparation Products

PPARγ-IN-2 Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+8613564774135 zijue.cai@tsbiochem.com United States 19881 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19699 58

View Lastest Price from PPARγ-IN-2 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PPARγ-IN-2 pictures 2024-10-28 PPARγ-IN-2
2682078-97-1
US $2500.00-1520.00 / mg 10g TargetMol Chemicals Inc.
  • PPARγ-IN-2 pictures
  • PPARγ-IN-2
    2682078-97-1
  • US $2500.00-1520.00 / mg
  • TargetMol Chemicals Inc.
PPARγ-IN-2 1H-Indole-3-carboxaldehyde, 2-[4-[[2-(1-pyrrolidinyl)ethyl]amino]-2-pyrimidinyl]- 2682078-97-1