ChemicalBook >> CAS DataBase List >>talmapimod
talmapimod
- CAS No.
- 309913-83-5
- Chemical Name:
- talmapimod
- Synonyms
- SCIO 469;Scios 469;talmapimod;Unii-B1E00kq6nt;TalMapiMod (SCIO-469);SCIO 469 - Talmapimod;SCIO 469 hydrochloride;Talmapimod hydrochloride;TALMAPIMOD;SCIO469;SCIO 469;cytotoxicity,multiple,inhibit,tumor,SCIO 469,SCIO469,cells,Hsp27,Inhibitor,phosphorylation,Talmapimod,p38 MAPK,myeloma
- CBNumber:
- CB81518535
- Molecular Formula:
- C27H30ClFN4O3
- Molecular Weight:
- 513
- MDL Number:
- MFCD11973651
- MOL File:
- 309913-83-5.mol
Last updated:2024-11-18 17:01:59
| Boiling point | 658.0±65.0 °C(Predicted) |
|---|---|
| Density | 1.29 |
| storage temp. | Desiccate at +4°C |
| solubility | DMSO: soluble |
| form | A crystalline solid |
| pka | 6.52±0.70(Predicted) |
| color | Pink to red |
| FDA UNII | B1E00KQ6NT |
| NCI Drug Dictionary | talmapimod |
talmapimod price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 29484 | SCIO 469 | 309913-83-5 | 1mg | $33 | 2024-03-01 | Buy |
| Cayman Chemical | 29484 | SCIO 469 | 309913-83-5 | 5mg | $120 | 2024-03-01 | Buy |
| Cayman Chemical | 29484 | SCIO 469 | 309913-83-5 | 10mg | $223 | 2024-03-01 | Buy |
| Tocris | 3528 | SCIO469hydrochloride ≥98%(HPLC) | 309913-83-5 | 10 | $257 | 2021-12-16 | Buy |
| Tocris | 3528 | SCIO469hydrochloride ≥98%(HPLC) | 309913-83-5 | 50 | $1078 | 2021-12-16 | Buy |
talmapimod Chemical Properties,Uses,Production
Uses
Talmapimod is a p38 mitogen-activated protein (MAP) kinase inhibitor. Talmapimod reduced human myeloma cell growth in vivo both at early and advanced phases of the disease in mouse xenograft models. Talmapimod that blocks tumor necrosis factor-α, interleukin-1β, and cyclooxygenase-2 synthesis in patients with active rheumatoid arthritis (RA)
Definition
ChEBI: An indolecarboxamide obtained by formal condensation of the carboxy group of 6-chloro-3-[(dimethylamino)(oxo)acetyl]-1-methylindole-5-carboxylic acid with the secondary amino group of (2S,5R)-1-[(4-fluorophenyl)methyl]-2, -dimethylpiperazine. It is a potent inhibitor of MAPK and exhibits anti-cancer properties.
talmapimod Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 76)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38631 | 58 | |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33338 | 58 |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
View Lastest Price from talmapimod manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-18 | Talmapimod
309913-83-5
|
US $48.00-187.00 / mg | 98% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-11-18 | Talmapimod
309913-83-5
|
US $48.00-187.00 / mg | 98% | 10g | TargetMol Chemicals Inc. |
-
- Talmapimod
309913-83-5
- US $48.00-187.00 / mg
- 98%
- TargetMol Chemicals Inc.
-
- Talmapimod
309913-83-5
- US $48.00-187.00 / mg
- 98%
- TargetMol Chemicals Inc.
talmapimod
6-Chloro-5-[[(2R,5S)-4-[(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]carbonyl]-N,N,1-trimethyl-alpha-oxo-1H-indole-3-acetamide
Unii-B1E00kq6nt
6-Chloro-5-[[(2R,5S)-4-[(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]carbonyl]-N,N,1-trimethyl-α-oxo-1H-Indole-3-acetamidehydrochloride
SCIO 469 hydrochloride
6-Chloro-5-[[(2R,5S)-4-[(4-fluorophenyl)Methyl]-2,5-diMethyl-1-piperazinyl]carbonyl]-N,N,1-triMethyl-α-oxo-1H-indole-3-acetaMide
SCIO 469
Scios 469
TalMapiMod (SCIO-469)
Talmapimod hydrochloride
TALMAPIMOD;SCIO469;SCIO 469
SCIO 469 - Talmapimod
1H-Indole-3-acetamide, 6-chloro-5-[[(2R,5S)-4-[(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]carbonyl]-N,N,1-trimethyl-α-oxo-
cytotoxicity,multiple,inhibit,tumor,SCIO 469,SCIO469,cells,Hsp27,Inhibitor,phosphorylation,Talmapimod,p38 MAPK,myeloma
309913-83-5
C27H30ClFN4O3
C27H30ClFN4O3HCl