Anti-TERF2-Interacting Protein, Anti-TERF2IP
- CAS No.
- Chemical Name:
- Anti-TERF2-Interacting Protein, Anti-TERF2IP
- Synonyms
- Anti-TERF2-Interacting Protein, Anti-TERF2IP;Monoclonal Anti-RAP1 antibody produced in mouse
- CBNumber:
- CB82096601
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Anti-TERF2-Interacting Protein, Anti-TERF2IP price More Price(1)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | R8154 | Monoclonal Anti-RAP1 antibody produced in mouse ~2?mg/mL, clone 4C8/1, purified immunoglobulin, buffered aqueous solution | 200μL | $529 | 2024-03-01 | Buy |
| Product number | Packaging | Price | Buy |
|---|---|---|---|
| R8154 | 200μL | $529 | Buy |
Anti-TERF2-Interacting Protein, Anti-TERF2IP Chemical Properties,Uses,Production
Uses
Monoclonal Anti-RAP1 antibody produced in mouse may be used in enzyme linked immunosorbent assay (ELISA) and immunoblotting.
General Description
Monoclonal Anti-RAP1 (mouse IgG2b isotype) is derived from the hybridoma 4C8/1 produced by the fusion of mouse myeloma cells (Sp2/0 Ag.14 cells) and splenocytes from BALB/c mice immunized with human RAP1. Ras-related protein 1 (RAP1) protein contains 399 amino acids with an acidic C-terminus featuring a 33 amino acid coiled-coil region and a bipartite nuclear localization signal. It is expressed ubiquitously, is located at telomeres and affects telomer length.
Biochem/physiol Actions
Rap1 (repressor/activator protein) helps to guard telomeres, assemble telomerase, and controls telomere length. At telomeres, Rap1 also participates in the suppression of non-homologous end joining (NHEJ). It involves in genomewide transcriptional modulation. Knockdown of Rap1 induces apoptosis in hepatocellular carcinoma cell line HepG2.