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N-Succinimidyl 6-maleimidohexanoate

CAS No.
55750-63-5
Chemical Name:
N-Succinimidyl 6-maleimidohexanoate
Synonyms
2,5-dioxopyrrolidin-1-yl 6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoate;EMCS;MCOSU;6-maleimidohexanoic acid N-hydroxylsuccinimide ester;6-MALEIMIDOCAPROIC ACID N-SUCCINIMIDYL ESTER;6-Maleimidohexanoic acid N-hydroxysuccinimide ester;(2,5-Dioxopyrrolidin-1-yl) 6-(2,5-dioxopyrrol-1-yl)hexanoate;EMCS Crosslinker;maleimide-(CH2)5-NHS;NHS-(CH2)5-Mal (EMCS)
CBNumber:
CB8212960
Molecular Formula:
C14H16N2O6
Molecular Weight:
308.29
MDL Number:
MFCD00043043
MOL File:
55750-63-5.mol
MSDS File:
SDS
Last updated:2023-09-04 15:51:00

N-Succinimidyl 6-maleimidohexanoate Properties

Melting point 70-73 °C(lit.)
Boiling point 480.6±47.0 °C(Predicted)
Density 1.40±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility chloroform: 100mg/mL
form powder
pka -2.21±0.20(Predicted)
color Off-white to pale brown
Sensitive Light & Moisture Sensitive & Hygroscopic
BRN 1499815
InChI InChI=1S/C14H16N2O6/c17-10-5-6-11(18)15(10)9-3-1-2-4-14(21)22-16-12(19)7-8-13(16)20/h5-6H,1-4,7-9H2
InChIKey VLARLSIGSPVYHX-UHFFFAOYSA-N
SMILES N1(CCCCCC(ON2C(=O)CCC2=O)=O)C(=O)C=CC1=O
CAS DataBase Reference 55750-63-5(CAS DataBase Reference)
FDA UNII AW858RP6BO

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xn,Xi
Risk Statements  36/37/38-40
Safety Statements  26-36/37-36
WGK Germany  3
8-10-21
HS Code  29280000
NFPA 704
0
2 1

N-Succinimidyl 6-maleimidohexanoate price More Price(56)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 63177 6-Maleimidohexanoic acid N-hydroxysuccinimide ester ≥98.0% (HPLC) 55750-63-5 25mg $215 2024-03-01 Buy
Sigma-Aldrich 568600 6-Maleimidohexanoic acid N-hydroxysuccinimide ester 98% 55750-63-5 500mg $244 2024-03-01 Buy
TCI Chemical S0428 N-Succinimidyl 6-Maleimidohexanoate [Cross-linking Reagent] >98.0%(N) 55750-63-5 1g $98 2024-03-01 Buy
Alfa Aesar H65996 6-Maleimidocaproic acid N-succinimidyl ester, 95% 55750-63-5 250mg $118.65 2024-03-01 Buy
Alfa Aesar H65996 6-Maleimidocaproic acid N-succinimidyl ester, 95% 55750-63-5 1g $372.65 2024-03-01 Buy
Product number Packaging Price Buy
63177 25mg $215 Buy
568600 500mg $244 Buy
S0428 1g $98 Buy
H65996 250mg $118.65 Buy
H65996 1g $372.65 Buy

N-Succinimidyl 6-maleimidohexanoate Chemical Properties,Uses,Production

Description

Mal-heptanoic NHS ester contains a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Chemical Properties

White to cream colored crystals

Uses

6-Maleimidohexanoic acid N-hydroxysuccinimide ester can be used in:

  • Synthesis of maleimide-activated carbohydrates for site-specific glycosylation of cysteine-containing peptides and proteins via maleimide-thiol ligation reaction.
  • Synthesis of a glucuronide prodrug of doxorubicin bearing a maleimide side chain as an antitumor agent.
  • Cross-linking oligonucleotides with the amino groups on the substrate to fabricate DNA microarrays.

6066-82-6
55750-53-3
55750-63-5
Synthesis of N-Succinimidyl 6-maleimidohexanoate from N-Hydroxysuccinimide and 6-Maleimidocaproic acid

N-Succinimidyl 6-maleimidohexanoate Preparation Products And Raw materials

Global( 318)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29791 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32957 60
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29881 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293 sales@sdzschem.com China 2930 58
Jinan Carbotang Biotech Co.,Ltd.
+8615866703830 figo.gao@foxmail.com China 8497 58
Changzhou PBpharmaceutical R&D Co.,Ltd
0519-83990708 info@pbpharm.com CHINA 498 58
Accela ChemBio Inc.
+1-858-6993322 info@accelachem.com United States 17453 58
Shanghai Worldyang Chemical Co.,Ltd.
+86-021-56795779 +8613651600618 sales@worldyachem.com China 1243 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58

View Lastest Price from N-Succinimidyl 6-maleimidohexanoate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-Succinimidyl 6-maleimidohexanoate pictures 2022-10-14 N-Succinimidyl 6-maleimidohexanoate
55750-63-5
US $0.00-0.00 / KG 1KG 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
N-Succinimidyl 6-maleimidohexanoate pictures 2021-07-13 N-Succinimidyl 6-maleimidohexanoate
55750-63-5
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
N-Succinimidyl 6-maleimidohexanoate pictures 2021-07-09 N-Succinimidyl 6-maleimidohexanoate
55750-63-5
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd

N-Succinimidyl 6-maleimidohexanoate Spectrum

Mal-heptanoic NHS ester EMCS N-Succinimidyl 6-maleimidohexanoate 6-Maleimidohexanoic acidN-hydroxysuccinimide ester≥ 98% (HPLC) N-(E-MALEIMIDOCAPROYLOXY)SUCCINIMIDE N-(EPSILON-MALEIMIDOCAPROYLOXY)SUCCINIMIDE N-[EPSILON-MALEIMIDOCAPROYLOXY]SUCCINIMIDE ESTER N-(6-MALEIMIDOCAPROYLOXY)SUCCINIMIDE 6-MaleiMidocaproic acid NHS 6-MaleiMidohexanoic acid N-hydroxysucciniMide este EMCS Crosslinker N-Succinimidyl 6-maleimidohexanoate 6-Maleimidohexanoic acid N-hydroxysuccinimide ester Mcosu N-SUCCINIMIDYL 6-MALEIMIDOCAPROATE N-SUCCINIMIDYL 6-MALEIMIDOHEXANOATE EPSILON-MALEIMIDOCAPROIC ACID N-HYDROXYSUCCINIMIDE ESTER N-SUCCINIMIDYL-6-MALEMIDOCAPROATE, 99% EPISILON-MALEIMIDOCAPROIC ACID N-*HYDROX YSUCCINIMID 6-maleimidohexanoic acid n-succinimidyl ester N-(6-Maleimidocaproyloxy)succinimideN-Succinimidyl-6-maleimidohexanoate 6-Maleimidocaproic acid N-hydroxysuccinimide ester N-Succinimidyl 6-Maleimidohexanoate [Cross-linking Reagent] 6-Maleimidocaproic acid N-succinimidyl ester, N-(ε-Maleimidocaproyloxy)succinimide, N-Succinimidyl 6-maleimidocaproate, EMCS 6-Maleimidohexanoic acid N-hydroxy succinimidyl ester NHS-(CH2)5-Mal (EMCS) N-(6-Maleimidocaproyloxy)succinimine N-(ε-Maleimidocaproyloxy)succinimide, N-Succinimidyl 6-maleimidocaproate 6-Maleimidohexanoic acid-NHS ester 1H-Pyrrole-1-hexanoicacid, 2,5-dihydro-2,5-dioxo-, 2,5-dioxo-1-pyrrolidinyl N-(EPSILON-MALEIMIDOCAPROYLOXY)SUCCI Maleimide-(CH2)5-COONHS 6-Maleimidohexanoic acid N-hydroxysuccinimide ester (EMCS) N-Succinimidyl 6-maleimidohexanoate(EMCS) 6-Maleimidohexanoic Acid N-hydroxy Succinimidyl Este 6-maleimidohexanoic acid N-hydroxylsuccinimide ester, N-succinimidyl-6-maleimidylhexanoate N-(6-Maleimidocaproyloxy)succinimide (EMCS) N-Succinimidyl6-Maleimidohexanoate[Cross-linkingReagent]> 1H-Pyrrole-1-hexanoic acid, 2,5-dihydro-2,5-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester N-(epsilon-Maleimidocaproyloxy) Succinimide extrapure, 98% (2,5-Dioxopyrrolidin-1-yl) 6-(2,5-dioxopyrrol-1-yl)hexanoate 2,5-dioxopyrrolidin-1-yl 6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoate 6-maleimidohexanoic acid N-hydroxylsuccinimide ester EMCS 6-MALEIMIDOCAPROIC ACID N-SUCCINIMIDYL ESTER 6-Maleimidohexanoic acid N-hydroxysuccinimide ester MCOSU Succinimide ester of 6-(maleimide) caproate Succinimide 6-(maleimide) caproate maleimide-(CH2)5-NHS 55750-63-5 N-Substituted Maleimides, Succinimides & Phthalimides N-Substituted Maleimides N-Substituted Succinimides Building Blocks Carbonyl Compounds Chemical Synthesis Cyclic Imides Organic Building Blocks N-Substituted Maleimides N-Substituted Maleimides, Succinimides & Phthalimides