rac-(2R*)-2-(Mercaptomethyl)-3-[(2-guanidinoethyl)thio]propanoic acid

CAS No.
Chemical Name:
rac-(2R*)-2-(Mercaptomethyl)-3-[(2-guanidinoethyl)thio]propanoic acid
Synonyms
Mergetpa;rac-(R*)-2-(Mercaptomethyl)-3-[(2-guanidinoethyl)thio]propanoic acid;rac-(2R*)-2-(Mercaptomethyl)-3-[(2-guanidinoethyl)thio]propanoic acid
CBNumber:
CB82328328
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
Last updated:2023-04-23 13:52:06

rac-(2R*)-2-(Mercaptomethyl)-3-[(2-guanidinoethyl)thio]propanoic acid Properties

Melting point >205°C (dec.)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly, Heated), Methanol (Very Slightly, Heated), Water (Slightly, Sonicated)
form Solid
color White to Off-White
Stability Air Sensitive, Hygroscopic

rac-(2R*)-2-(Mercaptomethyl)-3-[(2-guanidinoethyl)thio]propanoic acid Chemical Properties,Uses,Production

Uses

Mergetpa is a potent mercapto bi-product analogue inhibitor for human carboxypeptidase N. Carboxypeptidase N is a potent bradykinin and anaphylatoxin inactivator in plasma. Mergetpa improves rt-PA induced thrombolysis in a dog model of coronary artery thrombosis.

rac-(2R*)-2-(Mercaptomethyl)-3-[(2-guanidinoethyl)thio]propanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

Mergetpa rac-(2R*)-2-(Mercaptomethyl)-3-[(2-guanidinoethyl)thio]propanoic acid rac-(R*)-2-(Mercaptomethyl)-3-[(2-guanidinoethyl)thio]propanoic acid