(12R)-Lythrancane-8α,12-diol

CAS No.
32209-75-9
Chemical Name:
(12R)-Lythrancane-8α,12-diol
Synonyms
Lythrancepine I;(12R)-Lythrancane-8α,12-diol;7,11:12,16-Dimetheno-2H-azacycloheptadecino[2,1,17-de]quinolizine-5,19-diol, 1,3,3a,4,5,6,6a,17,18,19,20,20a-dodecahydro-10,13-dimethoxy-, (5S,6sR,19R,20aS)-
CBNumber:
CB82359586
Molecular Formula:
C27H35NO4
Molecular Weight:
437.57
MDL Number:
MOL File:
32209-75-9.mol

(12R)-Lythrancane-8α,12-diol Properties

Melting point 149-151 °c

(12R)-Lythrancane-8α,12-diol Chemical Properties,Uses,Production

Description

The macrocyclic alkaloid also occurs in Lythrurn anceps Male and is dextrorotatory having [α]20D + 59°. Two hydroxyl groups and two methoxyl groups are present. The structure and absolute configuration have been determined primarily from spectroscopic studies.

References

Fujita, Saeki., Chern. Cornrnun., 368 (1971) Absolute configuration: Fujita, Saeki., Chern. Pharrn. Bull., 19, 1515 (1971)

(12R)-Lythrancane-8α,12-diol Preparation Products And Raw materials

Raw materials

Preparation Products

(12R)-Lythrancane-8α,12-diol Lythrancepine I 7,11:12,16-Dimetheno-2H-azacycloheptadecino[2,1,17-de]quinolizine-5,19-diol, 1,3,3a,4,5,6,6a,17,18,19,20,20a-dodecahydro-10,13-dimethoxy-, (5S,6sR,19R,20aS)- 32209-75-9