ChemicalBook >> CAS DataBase List >>Methyl 1-acetyl-2-oxoindoline-6-carboxylate

Methyl 1-acetyl-2-oxoindoline-6-carboxylate

CAS No.
676326-36-6
Chemical Name:
Methyl 1-acetyl-2-oxoindoline-6-carboxylate
Synonyms
Nintedanib-002;methyl-1-acetyl2-oxoindole-6-carboxylate;Methyl 1-acetyl-2-oxoindoline-6-carboxylate;methyl 1-acetyl-2-oxo-3H-indole-6-carboxylate;Methyl 1-acetyl-2-oxo-2,3-dihydro-1H-indole-6-carboxylate;Methyl 1-acetyI-2-oxo-2,3-dihydro-1H-indoIe-6-carboxyIate;TIANFU-CHEM - Methyl 1-acetyl-2-oxoindoline-6-carboxylate;1-Acetyl-2,3-dihydro-2-oxo-1H-indole-6-carboxylic acid methy...;Nintedanib impurity 1/Methyl 1-Acetyl-2-oxoindoline-6-carboxylate;1-acetyl-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester
CBNumber:
CB82520764
Molecular Formula:
C12H11NO4
Molecular Weight:
233.22
MDL Number:
MFCD18251630
MOL File:
676326-36-6.mol
Last updated:2023-05-15 10:43:52

Methyl 1-acetyl-2-oxoindoline-6-carboxylate Properties

Boiling point 489.5±45.0 °C(Predicted)
Density 1.330
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka -1.94±0.20(Predicted)
color Off-White to Pale Red
FDA UNII AW3VK66XEB

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

Methyl 1-acetyl-2-oxoindoline-6-carboxylate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC M330593 Methyl1-Acetyl-2-oxoindoline-6-carboxylate 676326-36-6 1g $545 2021-12-16 Buy
Matrix Scientific 131561 Methyl1-acetyl-2-oxoindoline-6-carboxylate 97% 676326-36-6 5g $1432 2021-12-16 Buy
Matrix Scientific 131561 Methyl1-acetyl-2-oxoindoline-6-carboxylate 97% 676326-36-6 10g $2160 2021-12-16 Buy
ChemScene CS-M2961 methyl1-acetyl-2-oxoindoline-6-carboxylate 676326-36-6 1g $150 2021-12-16 Buy
ChemScene CS-M2961 methyl1-acetyl-2-oxoindoline-6-carboxylate 676326-36-6 5g $500 2021-12-16 Buy
Product number Packaging Price Buy
M330593 1g $545 Buy
131561 5g $1432 Buy
131561 10g $2160 Buy
CS-M2961 1g $150 Buy
CS-M2961 5g $500 Buy

Methyl 1-acetyl-2-oxoindoline-6-carboxylate Chemical Properties,Uses,Production

Uses

Methyl 1-Acetyl-2-oxoindoline-6-carboxylate is a reagent used in the preparation of Nintedanib (N478290), an angiokinase inhibitor and is used in the treatment of idiopathic pulmonary fibrosis. Also inhibits the process blood vessel formation which may be used to assist in cancer therapy.

108-24-7
14192-26-8
676326-36-6
Synthesis of Methyl 1-acetyl-2-oxoindoline-6-carboxylate from Acetic anhydride and Methyl 2-oxoindole-6-carboxylate

Methyl 1-acetyl-2-oxoindoline-6-carboxylate Preparation Products And Raw materials

Global( 89)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 18779 58
Beijing Cooperate Pharmaceutical Co.,Ltd
010-60279497 sales01@cooperate-pharm.com CHINA 1803 55
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
Anqing Chico Pharmaceutical Co., Ltd.
15380796838 chloewu@chicopharm.cn CHINA 340 58
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29884 58
Standardpharm Co. Ltd.
86-714-3992388 overseasales1@yongstandards.com United States 14332 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
Antai Fine Chemical Technology Co.,Limited
18503026267 info@antaichem.com CHINA 9636 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626 eric@witopchemical.com China 23541 58

View Lastest Price from Methyl 1-acetyl-2-oxoindoline-6-carboxylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Methyl 1-acetyl-2-oxoindoline-6-carboxylate pictures 2019-08-01 Methyl 1-acetyl-2-oxoindoline-6-carboxylate
676326-36-6
US $1.80-3.60 / KG 1KG 99% 88kg Career Henan Chemical Co
Methyl 1-acetyl-2-oxoindoline-6-carboxylate 1-Acetyl-2,3-dihydro-2-oxo-1H-indole-6-carboxylic acid methyl ester 1-acetyl-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester Nintedanib-002 methyl-1-acetyl2-oxoindole-6-carboxylate Nintedanib impurity 1/Methyl 1-Acetyl-2-oxoindoline-6-carboxylate 1H-Indole-6-carboxylic acid, 1-acetyl-2,3-dihydro-2-oxo-, methyl ester methyl 1-acetyl-2-oxo-3H-indole-6-carboxylate Methyl 1-acetyl-2-oxo-2,3-dihydro-1H-indole-6-carboxylate 1-Acetyl-2,3-dihydro-2-oxo-1H-indole-6-carboxylic acid methy... TIANFU-CHEM - Methyl 1-acetyl-2-oxoindoline-6-carboxylate Methyl 1-acetyI-2-oxo-2,3-dihydro-1H-indoIe-6-carboxyIate Methyl 1-acetyl-2-oxo-2,3-dihydro-1H-indole-6-carboxylate(Nintedanib N-acyl oxindole) 676326-36-6