MYRISTOYL-DL-CARNITINE CHLORIDE
- CAS No.
- 14919-38-1
- Chemical Name:
- MYRISTOYL-DL-CARNITINE CHLORIDE
- Synonyms
- MYRISTOYL-DL-CARNITINE CHLORIDE;(+/-)-MYRISTOYLCARNITINE CHLORIDE
- CBNumber:
- CB8254739
- Molecular Formula:
- C21H42ClNO4
- Molecular Weight:
- 408.02
- MDL Number:
- MFCD00063479
- MOL File:
- 14919-38-1.mol
MYRISTOYL-DL-CARNITINE CHLORIDE price More Price(2)
MYRISTOYL-DL-CARNITINE CHLORIDE Chemical Properties,Uses,Production
Uses
(+/-)-Myristoylcarnitine Chloride is a homolog of Acetylcarnitine Chloride (A171990), and an intermediate in lipid metabolism.
Biological Activity
(±)-myristoylcarnitine chloride is an agonist for cholinergic and a homolog of acetylcarnitine chloride (cat no. b6273).acetylcholine receptor (achr) is an integral membrane protein receptor for acetylcholine. there are two kinds of achrs: nicotinic acetylcholine receptors and muscarinic acetylcholine receptors.(±)-myristoylcarnitine chloride is a cholinergic agonist and an intermediate in lipid metabolism [1]. in retinal ganglion cells, acetylcarnitine and acetylcholine inhibited gabaergic responses to exogenous gaba and gabaergic inhibitory postsynaptic currents [2].in dogs with coronary ligation, (-)-carnitine chloride (lcc) (300 mg/kg) and acetyl (-)-carnitine chloride (alcc) (300 mg/kg) inhibited the ventricular arrhythmia. also, lcc and alcc improved oxidative phosphorylation rate and the mitochondrial function [1]. in the mouse hot plate test, acetyl-l-carnitine (alcar) (100 mg/kg) exhibited analgesia. while, u-73122 and neomycin (the phospholipase c (plc) inhibitors) blocked the increase of the pain threshold induced by alcar. licl that impairing phosphatidylinositol synthesis antagonized the antinociception in a dose-dependent way. pma and pdbu (pkc activators) blocked the increase of the pain threshold in a dose-dependent way. these results suggested that alcar analgesia required the participation of the plc-ip3 pathway [3].
MYRISTOYL-DL-CARNITINE CHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
MYRISTOYL-DL-CARNITINE CHLORIDE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15839 | 69 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14055 | 65 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8447 | 60 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44808 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8140 | 58 |
| Qingdao Tenglong microwave technology co., LTD. | 0532-83818797 18561885118 | market@tlwb.com.cn | China | 3944 | 58 |
| Shanghai Tachizaki Biomedical Research Center | 18014399201 | sales@chemlab-tachizaki.com | China | 2564 | 58 |
| ApexBio Technology | -- | sales@apexbt.com | United States | 6251 | 58 |
| BIOSYNTH AG | -- | welcome@biosynth.ch | Switzerland | 1308 | 60 |
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