2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate
- CAS No.
- 1041026-71-4
- Chemical Name:
- 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate
- Synonyms
- tert-butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate;tert-Butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate(2:1);2-Boc-2,6-diazaspiro[3.3]heptane Hemioxalate;6-diazaspiro[3.3]heptane-2-carboxylate oxalate;1-Boc-2,6-diazaspiro[3.3]heptanehemioxalate,97%;1-Boc-2,6-diazaspiro[3.3]heptane heMioxalate, 97%;2-Boc-2,6-Diazaspiro[3.3]heptane ethanedioate (2:1);2,6-Diazaspiro[3.3]heptane, N2-BOC protected hemioxalate;ert-Butyl 2,6-diazaspiro[3,3]heptane-2-carboxylate hemioxalate;tert-Butyl 2,6-diazaspiro[3,3]heptane-2-carboxylate hemioxalate
- CBNumber:
- CB82548539
- Molecular Formula:
- C22H38N4O8
- Molecular Weight:
- 486.56
- MDL Number:
- MFCD12404932
- MOL File:
- 1041026-71-4.mol
Melting point | 206-209℃ |
---|---|
storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
solubility | DMSO (Slightly, Heated), Methanol (Slightly, Sonicated) |
form | Solid |
color | White to Off-White |
Water Solubility | Slightly soluble in water. |
Stability | Hygroscopic |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H302-H312 | |||||||||
Precautionary statements | P264-P270-P280h-P301+P312a-P321-P501a | |||||||||
HS Code | 2933399990 | |||||||||
NFPA 704 |
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2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate price More Price(30)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Alfa Aesar | H63763 | 1-Boc-2,6-diazaspiro[3.3]heptane hemioxalate, 97% | 1041026-71-4 | 250mg | $163 | 2023-06-20 | Buy |
Alfa Aesar | H63763 | 1-Boc-2,6-diazaspiro[3.3]heptane hemioxalate, 97% | 1041026-71-4 | 1g | $519 | 2023-06-20 | Buy |
TRC | D417620 | 2,6-Diazaspiro[3.3]heptane-2-carboxylicAcidtert-ButylEsterHemioxalate | 1041026-71-4 | 100mg | $70 | 2021-12-16 | Buy |
Synthonix | D6051 | 2,6-Diazaspiro[3.3]heptane-2-carboxylicacidtert-butylesterhemioxalate 97.0% | 1041026-71-4 | 1g | $30 | 2021-12-16 | Buy |
Apolloscientific | OR312002 | 2,6-Diazaspiro[3.3]heptane,N2-BOCprotectedhemioxalate 97% | 1041026-71-4 | 1g | $58 | 2021-12-16 | Buy |
2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate Chemical Properties,Uses,Production
Chemical Properties
white to yellow Solid.
Uses
2,6-Diazaspiro[3.3]heptane-2-carboxylic Acid tert-Butyl Ester Hemioxylate is preparation of pyrimidine derivatives and related heterocycles as CDK inhibitors for treatment of diseases.
Uses
It is employed as a intermediate for pharmaceutical.
Preparation
Synthesis of 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate: Take a 500mL single-necked bottle, add 6-toluenesulfonyl-2,6-diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester (7g, 20mmol), dissolve in methanol (200mL), add magnesium chips (3.84 g) g, 0.16 mol, 8 equiv) and stirred at room temperature. The reaction solution gradually turned into a white viscous state with the dissolution of the magnesium scraps, and TLC showed that the reaction of the raw materials was completed. The solvent was removed by rotary evaporation, ether (150 mL) was added, stirred at room temperature for 1 h, filtered through celite, the filtrate was dried over anhydrous sodium sulfate, and an ethanol solution (3 mL) of anhydrous oxalic acid (0.89 g, 9.9 mmol, 0.5 equiv) was added dropwise, A white precipitate appeared immediately, which was filtered under reduced pressure to give 3.2 g of a colorless solid, 82%.
2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Suzhou Victorypharm Co.,Ltd. | +86-13916956214 | sales@victory-pharm.com | China | 1299 | 58 |
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
Hi-Tech Chemistry Corp | 0519-86626038 | yuhh@hitechem.com | CHINA | 810 | 58 |
Hangzhou FandaChem Co.,Ltd. | +8615858145714 | FandaChem@Gmail.com | China | 9087 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29880 | 58 |
Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2136 | 58 |
Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 17777 | 58 |
Shanghai Worldyang Chemical Co.,Ltd. | +86-021-56795779 +8613651600618 | sales@worldyachem.com | China | 1243 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
View Lastest Price from 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-12-13 | tert-butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate
1041026-71-4
|
US $0.00 / KG | 1KG | 97%min | 10KG | WUHAN FORTUNA CHEMICAL CO., LTD | ||
2022-09-08 | 6-(tert-butoxycarbonyl)-6-aza-2-azoniaspiro[3.3]heptane oxalate
1041026-71-4
|
US $0.00-0.00 / KG | 1KG | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
2019-07-06 | tert-butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate
1041026-71-4
|
US $1.00 / KG | 1KG | 95% | 500KG | Career Henan Chemical Co |
- tert-butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate
1041026-71-4
- US $0.00 / KG
- 97%min
- WUHAN FORTUNA CHEMICAL CO., LTD
- 6-(tert-butoxycarbonyl)-6-aza-2-azoniaspiro[3.3]heptane oxalate
1041026-71-4
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
- tert-butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate
1041026-71-4
- US $1.00 / KG
- 95%
- Career Henan Chemical Co
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