4-[6-Chloro-2-(4-cyano-phenylaMino)-pyriMidin-4-yloxy]-3,5-diMethyl-benzonitrile

4-[6-Chloro-2-(4-cyano-phenylaMino)-pyriMidin-4-yloxy]-3,5-diMethyl-benzonitrile structure

CAS No.: 1070377-34-2

Chemical Name:: 4-[6-Chloro-2-(4-cyano-phenylaMino)-pyriMidin-4-yloxy]-3,5-diMethyl-benzonitrile

Synonyms: Etravirine 5-Desbromo 6-Chloro Impurity;4-[6-chloro-2-(4-cyanoanilino)pyrimidin-4-yl]oxy-3,5-dimethyl-benzonitrile;4-[6-Chloro-2-(4-cyano-phenylaMino)-pyriMidin-4-ylo×y]-3,5-diMethyl-benzonitrile;4-[6-Chloro-2-(4-cyano-phenylaMino)-pyriMidin-4-yloxy]-3,5-diMethyl-benzonitrile;4-[[6-Chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile;Benzonitrile, 4-[[6-chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethyl-

CBNumber:: CB82562720

Molecular Formula:: C20H14ClN5O

Molecular Weight:: 375.81

MDL Number:: MFCD22421649

MOL File:: 1070377-34-2.mol

Last updated:2023-04-23 13:52:06

Request For Quotation

4-[6-Chloro-2-(4-cyano-phenylaMino)-pyriMidin-4-yloxy]-3,5-diMethyl-benzonitrile Properties

Melting point	>273°C (dec.)
Boiling point	602.9±65.0 °C(Predicted)
Density	1.38±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Acetone, DMSO (Slightly), Methanol (Slightly)
pka	-0.42±0.10(Predicted)
form	Solid
color	Off-White to Pale Yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

4-[6-Chloro-2-(4-cyano-phenylaMino)-pyriMidin-4-yloxy]-3,5-diMethyl-benzonitrile price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	C380823	4-[[6-Chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile	1070377-34-2	1mg	$45	2021-12-16	Buy
TRC	C380823	4-[[6-Chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile	1070377-34-2	2.5mg	$70	2021-12-16	Buy
TRC	C380823	4-[[6-Chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile	1070377-34-2	5mg	$115	2021-12-16	Buy
American Custom Chemicals Corporation	HCH0365321	4-((6-CHLORO-2-((4-CYANOPHENYL)AMINO)PYRIMIDIN-4-YL)OXY)-3,5-DIMETHYLBENZONITRILE 95.00%	1070377-34-2	5MG	$501.81	2021-12-16	Buy
Matrix Scientific	091951	4-((6-Chloro-2-((4-cyanophenyl)amino)pyrimidin-4-yl)oxy)-3,5-dimethylbenzonitrile 95+%	1070377-34-2	250mg	$521	2021-12-16	Buy

Product number	Packaging	Price	Buy
C380823	1mg	$45	Buy
C380823	2.5mg	$70	Buy
C380823	5mg	$115	Buy
HCH0365321	5MG	$501.81	Buy
091951	250mg	$521	Buy

4-[6-Chloro-2-(4-cyano-phenylaMino)-pyriMidin-4-yloxy]-3,5-diMethyl-benzonitrile Chemical Properties,Uses,Production

Uses

4-[[6-Chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile is a by-product from the synthesis of Etravirine-d8 (E937003). Etravirine-d8 is a novel labelled HIV reverse transcriptase inhibitor useful in treatment of HIV infection.

4-[6-Chloro-2-(4-cyano-phenylaMino)-pyriMidin-4-yloxy]-3,5-diMethyl-benzonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

4-[6-Chloro-2-(4-cyano-phenylaMino)-pyriMidin-4-yloxy]-3,5-diMethyl-benzonitrile Suppliers

Global( 18)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
LEAP CHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	24738	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131980	58
Nanjing Chalf-Pharm Technology Co., Ltd.	025-57018978 18251899859	sales@chalf-pharm.com	China	5884	50
Aikon International Limited	025-66113011 13155353615	qzhang@aikonchem.com	China	15396	58
Jinan Ruisi Pharmaceutical Technology Co., LTD	0531-69900633 18340090523	changyuan20@163.com	China	1980	58
Beijing xinyanhui pharmaceutical research and development co., LTD	13969155946	1461866103@qq.com	China	16111	58
Meng Cheng Technology (Shanghai) Co., LTD	400-820-6829	sales@mitachieve.com	China	8864	58
Hubei Xinyang Medical Technology Co., Ltd	15347293736 15347293736	2853117764@qq.com	China	8378	58
Shanghai Dexuan Pharmaceutical Technology Co., Ltd	1701086315	dexuanpharma@126.com	China	9478	58

Supplier	Advantage
LEAP CHEM CO., LTD.	58
LEAPCHEM CO., LTD.	58
Amadis Chemical Company Limited	58
Nanjing Chalf-Pharm Technology Co., Ltd.	50
Aikon International Limited	58
Jinan Ruisi Pharmaceutical Technology Co., LTD	58
Beijing xinyanhui pharmaceutical research and development co., LTD	58
Meng Cheng Technology (Shanghai) Co., LTD	58
Hubei Xinyang Medical Technology Co., Ltd	58
Shanghai Dexuan Pharmaceutical Technology Co., Ltd	58

1070377-34-2(4-[6-Chloro-2-(4-cyano-phenylaMino)-pyriMidin-4-yloxy]-3,5-diMethyl-benzonitrile)Related Search:

4-[[4-[[4-[(E)-2-cyanoethenyl]-2,6-dimethyl-phenyl]amino]pyrimidin-2-yl]amino]benzonitrile Ethyl (2R,4R)-4-methyl-2-piperidinecarboxylate Etravirine

4-[6-Chloro-2-(4-cyano-phenylaMino)-pyriMidin-4-yloxy]-3,5-diMethyl-benzonitrile 4-[6-Chloro-2-(4-cyano-phenylaMino)-pyriMidin-4-ylo×y]-3,5-diMethyl-benzonitrile 4-[[6-Chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile Etravirine 5-Desbromo 6-Chloro Impurity 4-[6-chloro-2-(4-cyanoanilino)pyrimidin-4-yl]oxy-3,5-dimethyl-benzonitrile Benzonitrile, 4-[[6-chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethyl- 1070377-34-2