2-chloroethanesulfonyl chloride
- CAS No.
- 1622-32-8
- Chemical Name:
- 2-chloroethanesulfonyl chloride
- Synonyms
- oroethanesuL;2-chloroethanesulfochloride;2-chloroethylsulfonylchloride;2-chloro-ethanesulfonylchlorid;2-CHLOROETHANESULFONYL CHLORIDE;2-chloroethanesulfochloride[qr];2-CHLOROETHANESULPHONYL CHLORIDE;(2-chloroethyl)sulphonyl chloride;beta-chloroethanesulfonylchloride;2-chloroethylsulfonylchloride[qr]
- CBNumber:
- CB8257215
- Molecular Formula:
- C2H4Cl2O2S
- Molecular Weight:
- 163.02
- MDL Number:
- MFCD00007461
- MOL File:
- 1622-32-8.mol
| Melting point | 3 °C |
|---|---|
| Boiling point | 84-86 °C15 mm Hg(lit.) |
| Density | 1.56 g/mL at 25 °C(lit.) |
| vapor pressure | 15 mm Hg ( 84 °C) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Refrigerator |
| form | Liquid |
| color | Clear slightly yellow to brown |
| Water Solubility | Reacts with water. |
| Sensitive | Moisture Sensitive |
| BRN | 1751202 |
| InChI | InChI=1S/C2H4Cl2O2S/c3-1-2-7(4,5)6/h1-2H2 |
| InChIKey | VHCSBTPOPKFYIU-UHFFFAOYSA-N |
| SMILES | C(S(Cl)(=O)=O)CCl |
| CAS DataBase Reference | 1622-32-8(CAS DataBase Reference) |
| FDA UNII | AET6VQ5A3Q |
| EPA Substance Registry System | 2-Chloro-ethanesulfonyl chloride (1622-32-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H314-H330-H335 | |||||||||
| Precautionary statements | P260-P270-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338 | |||||||||
| Hazard Codes | T+ | |||||||||
| Risk Statements | 22-26-34-36 | |||||||||
| Safety Statements | 26-28-36/37/39-45-23 | |||||||||
| RIDADR | UN 3390 6.1/PG 1 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | KI8060000 | |||||||||
| F | 10-19 | |||||||||
| TSCA | Y | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29049090 | |||||||||
| Toxicity | mouse,LC50,inhalation,250mg/m3/4H (250mg/m3),Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 15(6), Pg. 59, 1971. | |||||||||
| NFPA 704 |
|
2-chloroethanesulfonyl chloride price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 302325 | 2-Chloroethanesulfonyl chloride 96% | 1622-32-8 | 5g | $45.7 | 2024-03-01 | Buy |
| Sigma-Aldrich | 302325 | 2-Chloroethanesulfonyl chloride 96% | 1622-32-8 | 25g | $112 | 2024-03-01 | Buy |
| TCI Chemical | C1142 | 2-Chloroethanesulfonyl Chloride >95.0%(GC)(T) | 1622-32-8 | 25g | $52 | 2024-03-01 | Buy |
| TCI Chemical | C1142 | 2-Chloroethanesulfonyl Chloride >95.0%(GC)(T) | 1622-32-8 | 100g | $171 | 2024-03-01 | Buy |
| Alfa Aesar | A15377 | 2-Chloroethanesulfonyl chloride, 98% | 1622-32-8 | 10g | $54.4 | 2024-03-01 | Buy |
2-chloroethanesulfonyl chloride Chemical Properties,Uses,Production
Chemical Properties
CLEAR SLIGHTLY YELLOW TO BROWN LIQUID
Uses
2-Chloroethanesulfonyl chloride was used in one-pot sulfonylation/intramolecular thia-Michael protocol for the synthesis of 1,5,2-dithiazepine 1,1-dioxides. It was also used in synthesis of vinyl sulfonamides with a furan, carbocyclic, semi cyclic or acyclic 1,3-diene moiety.
Application
As a precursor of the bis-electrophilic synthon vinylsulfonyl chloride, 2-chloroethanesulfonyl chloride can react with a wide range of bis-nucleophilic synthons, such as substituted 2-amino alcohols, to generate 7-membered sultams. This compound can be used in lieu of vinylsulfonyl chloride via a domino elimination– amidation reaction[1-2].
General Description
A liquid. Density 1.56 g / cm3. Flash point exceeds 230°F.
Air & Water Reactions
Reacts with water to produce corrosive and toxic gaseous hydrogen chloride.
Reactivity Profile
2-CHLOROETHANESULFONYL CHLORIDE is incompatible with strong oxidizing agents, alcohols, amines, alkali. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].
References
[1] Qin Zang. “Synthesis of a Library of 1,5,2-Dithiazepine 1,1-Dioxides. Part 1: A One-Pot Sulfonylation/Thia-Michael Protocol.” Heterocycles 86 2 (2012).
[2] Victor O Rogachev, Peter Metz. “Thermal and high pressure intramolecular Diels–Alder reaction of vinylsulfonamides.” Nature Protocols 1 6 (2007): 3076–3087.
2-chloroethanesulfonyl chloride Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Lidu New Material Technology Co., Ltd | +undefined+86-19307248857 | liduxcl@163.com | China | 1134 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29811 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30240 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | China | 52849 | 58 |
| Henan Alfa Chemical Co., Ltd | China | 13225 | 58 | ||
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| Nanjing Doge Biomedical Technology Co., Ltd | +86-25-58227606 +86-15305155328 | sales@dogechemical.com | China | 4128 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24727 | 58 |
View Lastest Price from 2-chloroethanesulfonyl chloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-29 | 2-CHLOROETHANESULFONYL CHLORIDE
1622-32-8
|
US $0.00 / kg | 10kg | 97% | 20tons | Hubei Lidu New Material Technology Co., Ltd | |
 |
2020-01-09 | 2-CHLOROETHANESULFONYL CHLORIDE
1622-32-8
|
US $9.80 / KG | 1g | ≥99% | 100kg | Career Henan Chemical Co |
-
- 2-CHLOROETHANESULFONYL CHLORIDE
1622-32-8
- US $0.00 / kg
- 97%
- Hubei Lidu New Material Technology Co., Ltd
-
- 2-CHLOROETHANESULFONYL CHLORIDE
1622-32-8
- US $9.80 / KG
- ≥99%
- Career Henan Chemical Co