ChemicalBook >> CAS DataBase List >>4-fluoro-2-Methoxy-5-nitroaniline
4-fluoro-2-Methoxy-5-nitroaniline
- CAS No.
- 1075705-01-9
- Chemical Name:
- 4-fluoro-2-Methoxy-5-nitroaniline
- Synonyms
- 4-fluoro-2-methoxy;AZD9291 intermediates;uoro-2-methoxy-5-nitroaniL;4-Fluoro-2-mehoxy-5-nitroaniline;4-fluoro-2-Methoxy-5-nitroaniline;4-Fluoro-2-Methoxy-5-nitrobenzenaMine;4-fluoro-2-methoxy-5-nitrophenylamine;4-Fluoro-2-methoxy-5-nitroaniline 95+%;Benzenamine, 4-fluoro-2-methoxy-5-nitro-;4-fluoro-2-Methoxy-5-nitroaniline ISO 9001:2015 REACH
- CBNumber:
- CB82670450
- Molecular Formula:
- C7H7FN2O3
- Molecular Weight:
- 186.14
- MDL Number:
- MFCD23098941
- MOL File:
- 1075705-01-9.mol
- MSDS File:
- SDS
Last updated:2024-08-13 12:20:35
Melting point | 130 °C |
---|---|
Boiling point | 354.8±37.0 °C(Predicted) |
Density | 1.412±0.06 g/cm3(Predicted) |
storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
form | powder to crystal |
pka | 2.31±0.10(Predicted) |
color | Light yellow to Brown |
InChI | InChI=1S/C7H7FN2O3/c1-13-7-2-4(8)6(10(11)12)3-5(7)9/h2-3H,9H2,1H3 |
InChIKey | FYSIGSQCZXQTIH-UHFFFAOYSA-N |
SMILES | C1(N)=CC([N+]([O-])=O)=C(F)C=C1OC |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H302+H312+H332-H315-H319-H335 | |||||||||
Precautionary statements | P261-P271-P280 | |||||||||
HS Code | 2921420090 | |||||||||
NFPA 704 |
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4-fluoro-2-Methoxy-5-nitroaniline price More Price(30)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TCI Chemical | F1246 | 4-Fluoro-2-methoxy-5-nitroaniline | 1075705-01-9 | 5G | $33 | 2024-03-01 | Buy |
TCI Chemical | F1246 | 4-Fluoro-2-methoxy-5-nitroaniline | 1075705-01-9 | 25G | $98 | 2024-03-01 | Buy |
TRC | F472455 | 4-Fluoro-2-methoxy-5-nitroaniline | 1075705-01-9 | 10g | $140 | 2021-12-16 | Buy |
TRC | F472455 | 4-Fluoro-2-methoxy-5-nitroaniline | 1075705-01-9 | 25g | $275 | 2021-12-16 | Buy |
AK Scientific | 9516AF | 4-Fluoro-2-methoxy-5-nitroaniline | 1075705-01-9 | 100g | $321 | 2021-12-16 | Buy |
4-fluoro-2-Methoxy-5-nitroaniline Chemical Properties,Uses,Production
Uses
4-Fluoro-2-methoxy-5-nitroaniline is used as a reagent for preparing the anticancer drug Mereletinib.
Synthesis
4-FLUORO-2-METHOXYANILINE(551 mg, 3.90 mmol) is dissolved in dichloromethane (39.0 mL), concentrated sulfuric acid (1.85 mL) is added dropwise with stirring under ice-cooling, and then concentrated nitric acid (267 μL, 5.85 mmol) is added dropwise. After stirring for 3 hours under ice-cooling, saturated aqueous sodium bicarbonate was added until pH 8 was reached. After washing with saturated aqueous sodium bicarbonate solution, washing with saturated brine, the organic layer was dried over sodium sulfate and evaporated under reduced pressure to obtain 675 mg of the 4-fluoro-2-Methoxy-5-nitroaniline (yield 93%).
4-fluoro-2-Methoxy-5-nitroaniline Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 392)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Golden Pharma Co., Limited | +undefined18958062155 | sales@zjgoldpharm.com | China | 5905 | 58 |
Jiangsu Boquan Biotechnology Co., Ltd. | +86-18168774353 | boquanshengwu003@boquansw.com | China | 248 | 58 |
Jinan Dexinjia Bio&Tech Co., Ltd | +86-0531-82375893 +86-15064117275 | sales@jndxj.com | China | 1265 | 58 |
Lianhe Aigen Pharmatech Co.,Ltd. | +undefined+undefined18918657159 | sales-Aigen@lianhetech.com | China | 314 | 58 |
Cangzhou Kangrui Pharma Tech Co. Ltd., | +8618632776803 | cangzhoukangrui@126.com | China | 733 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12490 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5895 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20291 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
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View Lastest Price from 4-fluoro-2-Methoxy-5-nitroaniline manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-09-26 | 4-Fluoro-2-Methoxy-5-Nitroaniline
1075705-01-9
|
US $5.00-2.00 / KG | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | ||
2024-04-09 | 4-fluoro-2-Methoxy-5-nitroaniline
1075705-01-9
|
US $5.00-0.10 / KG | 1KG | 98% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | ||
2023-09-25 | 4-Fluoro-2-Methoxy-5-Nitroaniline
1075705-01-9
|
US $50.00 / g | 1g | 99% | 2 kg | Anhui Yisheng Technology Co., LTD |
- 4-Fluoro-2-Methoxy-5-Nitroaniline
1075705-01-9
- US $5.00-2.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
- 4-fluoro-2-Methoxy-5-nitroaniline
1075705-01-9
- US $5.00-0.10 / KG
- 98%
- Henan Fengda Chemical Co., Ltd
- 4-Fluoro-2-Methoxy-5-Nitroaniline
1075705-01-9
- US $50.00 / g
- 99%
- Anhui Yisheng Technology Co., LTD
1075705-01-9(4-fluoro-2-Methoxy-5-nitroaniline)Related Search:
4-fluoro-2-Methoxy-5-nitroaniline
2-Amino-5-fluoro-4-nitroanisole, 4-Fluoro-5-nitro-o-anisidine
4-Fluoro-2-Methoxy-5-nitrobenzenaMine
Benzenamine, 4-fluoro-2-methoxy-5-nitro-
4-fluoro-2-methoxy-5-nitrophenylamine
4-Fluoro-2-methoxy-5-nitroaniline 95+%
AZD9291 intermediates
uoro-2-methoxy-5-nitroaniL
4-Fluoro-2-mehoxy-5-nitroaniline
4-fluoro-2-Methoxy-5-nitroaniline ISO 9001:2015 REACH
4-fluoro-2-methoxy-5-nitroaniline
Molecular Formula: C7H7FN2O3
Molecular Weight: 186.14
4-fluoro-2-methoxy
1075705-01-9
075705-01-9
AZD9291
API
1075705-01-9