FK-3657
- CAS No.
- 167838-64-4
- Chemical Name:
- FK-3657
- Synonyms
- FK-3657;(E)-3-(6-acetamidopyridin-3-yl)-N-[2-[2,4-dichloro-N-methyl-3-[(2-methylquinolin-8-yl)oxymethyl]anilino]-2-oxoethyl]prop-2-enamide;(E)-3-(6-Acetamidopyridin-3-yl)-N-(2-((2,4-dichloro-3-(((2-methylquinolin-8-yl)oxy)methyl)phenyl)(methyl)amino)-2-oxoethyl)acrylamide;3-[6-(Acetylamino)-3-pyridinyl]-N-[2-[[2,4-dichloro-3-[[(2-methyl-8-quinolinyl)oxy]methyl]phenyl]methylamino]-2-oxoethyl]-(E)-2-propenamide;2-Propenamide, 3-[6-(acetylamino)-3-pyridinyl]-N-[2-[[2,4-dichloro-3-[[(2-methyl-8-quinolinyl)oxy]methyl]phenyl]methylamino]-2-oxoethyl]-, (2E)-
- CBNumber:
- CB82716226
- Molecular Formula:
- C30H27Cl2N5O4
- Molecular Weight:
- 592.47
- MDL Number:
- MFCD00952144
- MOL File:
- 167838-64-4.mol
Last updated:2022-12-21 16:56:50
| Melting point | 146-150 °C |
|---|---|
| Boiling point | 907.1±65.0 °C(Predicted) |
| Density | 1.386±0.06 g/cm3(Predicted) |
| pka | 12.06±0.46(Predicted) |
| FDA UNII | 262AL91J0Y |
FK-3657 Chemical Properties,Uses,Production
Uses
3-[6-(Acetylamino)-3-pyridinyl]-N-[2-[[2,4-dichloro-3-[[(2-methyl-8-quinolinyl)oxy]methyl]phenyl]methylamino]-2-oxoethyl]-(E)-2-propenamide, or FR 173657, is a nonpeptide bradyykinin B2 receptor antagonist. It is an orally-active noncompetitive antagonist with high affinity to the B2, that inhibits BK-induced bronchoconstriction and B2 receptor-mediated phosphatidylinositol hydrolysis
FK-3657 Preparation Products And Raw materials
Raw materials
Preparation Products
FK-3657 Suppliers
Global( 2)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| SPIRO PHARMA | eric_feng1954@126.com | China | 9254 | 55 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| SPIRO PHARMA | 55 |
FK-3657
(E)-3-(6-acetamidopyridin-3-yl)-N-[2-[2,4-dichloro-N-methyl-3-[(2-methylquinolin-8-yl)oxymethyl]anilino]-2-oxoethyl]prop-2-enamide
2-Propenamide, 3-[6-(acetylamino)-3-pyridinyl]-N-[2-[[2,4-dichloro-3-[[(2-methyl-8-quinolinyl)oxy]methyl]phenyl]methylamino]-2-oxoethyl]-, (2E)-
3-[6-(Acetylamino)-3-pyridinyl]-N-[2-[[2,4-dichloro-3-[[(2-methyl-8-quinolinyl)oxy]methyl]phenyl]methylamino]-2-oxoethyl]-(E)-2-propenamide
(E)-3-(6-Acetamidopyridin-3-yl)-N-(2-((2,4-dichloro-3-(((2-methylquinolin-8-yl)oxy)methyl)phenyl)(methyl)amino)-2-oxoethyl)acrylamide
167838-64-4