N-nervonoyl-D-erythro-sphinganine
- CAS No.
- 352518-80-0
- Chemical Name:
- N-nervonoyl-D-erythro-sphinganine
- Synonyms
- C24:1-dihydro-Ceramide;N-nervonoyl-D-erythro-sphinganine;C24:1 Dihydroceramide (d18:0/24:1(15Z));N-NERVONOYL-D-ERYTHRO-SPHINGANINE;C24:1 DIHYDROCERAMIDE (D18:0/24:1(15Z));15-Tetracosenamide, N-[(1S,2R)-2-hydroxy-1-(hydroxymethyl)heptadecyl]-, (15Z)-
- CBNumber:
- CB82720762
- Molecular Formula:
- C42H83NO3
- Molecular Weight:
- 650.11
- MDL Number:
- MFCD02259305
- MOL File:
- 352518-80-0.mol
N-nervonoyl-D-erythro-sphinganine Chemical Properties,Uses,Production
Uses
C24:1 Dihydroceramide has been used as a standard in quadrupole time-of-flight (Q-TOF) mass spectrometry for the measurement of sphingolipid metabolites in adipose tissue. It has also been used a standard in diacylglycerol kinase (DGK) assay to quantify dihydroceramides in CLN9-deficient cells.
Definition
ChEBI: N-[(15Z)-tetracosenoyl]sphinganine is a dihydroceramide in which the ceramide N-acyl group is specified as (15Z)-tetracosenoyl (nervonoyl). It has a role as a mouse metabolite. It is a C24:1-sphinganine and a Cer(d42:1). It is functionally related to a (15Z)-tetracosenoic acid.
Biological Activity
C24:1 Dihydroceramide is a synthetic dihydroceramide. Dihydroceramides are reduced to ceramides by the enzyme dihydroceramide desaturase. Elevated levels of serum 24:1 DHC has been observed in patients with history of hepatocellular carcinoma (HCC) pre-orthopic liver transplantation (OLT), compared to patients with no prior HCC. Therefore, 24:1 DHC can be used as a HCC biomarker in post-OLT patients.
N-nervonoyl-D-erythro-sphinganine Preparation Products And Raw materials
Raw materials
Preparation Products
N-nervonoyl-D-erythro-sphinganine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
| Alfa Chemistry | Info@alfa-chemistry.com | United States | 24072 | 58 | |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 18021050169 | market@aladdin-e.com | China | 25003 | 65 |
| Yichang Zhongyitai Trading Co., Ltd. | 0717-6449896 13886658719 | root@zhongyitai.com | China | 1977 | 58 |
| Alfa Chemistry | 1-516-6625404 | support@alfa-chemistry.com | United States | 9171 | 60 |
| Codow Chemical Co.,Ltd. | 18620099427 | amy@howeipharm.com | China | 17687 | 55 |
| Chengdu Dianchun Technology Co., Ltd | 400-1166-196 18502815961 | cdhxsj@163.com | China | 14603 | 60 |
| Shanghai Jizhi Biochemical Technology Co. Ltd. | 4009004166/18616739031 18616739031 | 3007523370@qq.com | China | 52693 | 58 |
| Auonsi (Shanghai) Biology Technology Co., Ltd. | 400-1107768 15058188853 | 478133536@qq.com | China | 8552 | 58 |