ChemicalBook >> CAS DataBase List >>5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl ester
5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl ester
- CAS No.
- 1416324-85-0
- Chemical Name:
- 5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl ester
- Synonyms
- CU-CPT22;CU-CPT22 >=98% (HPLC);hexyl 3,4,6-trihydroxy-2-methoxy-5-oxo-5H-benzo[7]annulene-8-carboxylate;inhibit,CU CPT22,Inhibitor,CU-CPT22,Toll-like Receptor (TLR),CUCPT22,CU-CPT-22;3,4,6-Trihydroxy-2-methoxy-5-oxo-5H-benzocycloheptene-8-carboxylic acid hexyl ester;5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl ester
- CBNumber:
- CB82750594
- Molecular Formula:
- C19H22O7
- Molecular Weight:
- 362.37
- MDL Number:
- MFCD26406409
- MOL File:
- 1416324-85-0.mol
- MSDS File:
- SDS
Last updated:2023-06-30 15:45:59
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS08,GHS09 |
|---|---|
| Signal word | Danger |
| Hazard statements | H334-H410 |
| Precautionary statements | P261-P273-P342+P311-P501 |
| Hazard Codes | N |
| Risk Statements | 50/53 |
| Safety Statements | 60-61 |
| RIDADR | UN 3077 9 / PGIII |
5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl ester price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 15244 | CU CPT 22 | 1416324-85-0 | 1mg | $57 | 2024-03-01 | Buy |
| Cayman Chemical | 15244 | CU CPT 22 | 1416324-85-0 | 10mg | $275 | 2024-03-01 | Buy |
| Cayman Chemical | 15244 | CU CPT 22 | 1416324-85-0 | 5mg | $152 | 2024-03-01 | Buy |
| Tocris | 4884 | CUCPT22 ≥98%(HPLC) | 1416324-85-0 | 10 | $266 | 2021-12-16 | Buy |
| Tocris | 4884 | CUCPT22 ≥98%(HPLC) | 1416324-85-0 | 50 | $1055 | 2021-12-16 | Buy |
5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl ester Chemical Properties,Uses,Production
Description
CU CPT 22 is an antagonist of toll-like receptor 1 (TLR1) and TLR2 heterodimers (TLR1/TLR2; Ki = 0.41 μM). It inhibits nitric oxide (NO) production induced by the TLR2 agonist Pam3CSK4 in RAW 264.7 cells (IC50 = 0.58 μM). It is selective for TLR1/TLR2 over TLR2/TLR6 and TLR3, -4, and -7 homodimers, as well as 10 kinases at 0.5 μM. CU CPT 22 (8 μM) inhibits Pam3CSK4-induced release of TNF-α and IL-1β in RAW 264.7 cells by 60 and 95%, respectively.
storage
Store at -20°C
5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl ester Suppliers
Global( 45)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
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| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973130 4009686088 | 3193328036@qq.com | China | 29786 | 68 |
5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl ester
CU-CPT22
hexyl 3,4,6-trihydroxy-2-methoxy-5-oxo-5H-benzo[7]annulene-8-carboxylate
3,4,6-Trihydroxy-2-methoxy-5-oxo-5H-benzocycloheptene-8-carboxylic acid hexyl ester
CU-CPT22 >=98% (HPLC)
inhibit,CU CPT22,Inhibitor,CU-CPT22,Toll-like Receptor (TLR),CUCPT22,CU-CPT-22
1416324-85-0