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1,10-Phenanthroline hydrate

CAS No.
5144-89-8
Chemical Name:
1,10-Phenanthroline hydrate
Synonyms
1,10-PHENANTHROLINE MONOHYDRATE;ORTHO-PHENANTHROLINE;Phenanthroline Monohydrate;1,10-PHENANTHROLINE H2O;O-PHENANTHROLINE MONOHYDRATE;10-Phenanthroline monohydrate;1,10-Phenanthroline, ACS, 99%;PHENYLANTHROLINE HYDRATE 1,10-;1,10-PHENANTHROLINE AR;Black bone vine extract
CBNumber:
CB8290304
Molecular Formula:
C12H8N2.H2O
Molecular Weight:
198.22
MDL Number:
MFCD00149973
MOL File:
5144-89-8.mol
MSDS File:
SDS
Last updated:2024-11-17 19:25:39

1,10-Phenanthroline hydrate Properties

Melting point 100-104 °C(lit.)
Density 1.10
vapor density 6.2 (vs air)
storage temp. Sealed in dry,Room Temperature
solubility methanol: soluble200MM (Stock solution is stable for months at –20° C.)
form Needle-Like Crystals
color Off-white, may become cream-colored during storage
Water Solubility <0.01 g/100 mL at 21 ºC
Merck 14,7214
BRN 4008096
Stability Stable. Incompatible with iron, other heavy metals, strong oxidizing agents, strong acids.
CAS DataBase Reference 5144-89-8(CAS DataBase Reference)
FDA UNII KSX215X00E
EPA Substance Registry System 1,10-Phenanthroline, monohydrate (5144-89-8)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS06,GHS09
Signal word  Danger
Hazard statements  H301-H410
Precautionary statements  P273-P301+P310+P330
Hazard Codes  T,N
Risk Statements  25-50/53
Safety Statements  45-60-61
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  SF8437000
TSCA  Yes
HazardClass  6.1
PackingGroup  III
HS Code  29339990
Toxicity LD50 orally in Rabbit: 132 mg/kg
NFPA 704
1
2 0

1,10-Phenanthroline hydrate price More Price(72)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 77500 1,10-Phenanthroline monohydrate for the spectrophotometric determination of Fe, Pd, V, ≥99.0% 5144-89-8 5G $61.4 2024-03-01 Buy
Sigma-Aldrich 77500 1,10-Phenanthroline monohydrate for the spectrophotometric determination of Fe, Pd, V, ≥99.0% 5144-89-8 25g $242 2024-03-01 Buy
Sigma-Aldrich 320056 1,10-Phenanthroline monohydrate ACS reagent, 99% 5144-89-8 5g $70.8 2024-03-01 Buy
Sigma-Aldrich 320056 1,10-Phenanthroline monohydrate ACS reagent, 99% 5144-89-8 25g $209 2024-03-01 Buy
Sigma-Aldrich 1.07225 1,10-Phenanthroline monohydrate GR ACS 5144-89-8 10g $242 2024-03-01 Buy
Product number Packaging Price Buy
77500 5G $61.4 Buy
77500 25g $242 Buy
320056 5g $70.8 Buy
320056 25g $209 Buy
1.07225 10g $242 Buy

1,10-Phenanthroline hydrate Chemical Properties,Uses,Production

Chemical Properties

white crystals or powder

Uses

When complexed with copper, it possesses nuclease activity that has been used to study DNA-protein interactions.
1,10-Phenanthroline monohydrate is an aromatic nitrogen heterocycle that may be used as a chelating agent in the preparation of metal-chelate complexes.

Uses

1,10-Phenanthroline monohydrate is useful to study the DNA-protein interactions due to its nuclease activity. It is used as a redox indicator and reagent for spectrophotometric assay of silver. It acts as a chelating ligand for the determination of Fe, Pd and V. It also acts as a matrix metalloproteinase inhibitor. It is a photometric reagent for iron, which forms a red chelate with ferrous (iron II) ion.

General Description

White crystalline powder or solid. Slight odor.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

1,10-Phenanthroline hydrate is incompatible with strong oxidizers. 1,10-Phenanthroline hydrate is also incompatible with strong acids. 1,10-Phenanthroline hydrate forms complex compounds with ferrous ions. .

Fire Hazard

Flash point data for 1,10-Phenanthroline hydrate are not available. 1,10-Phenanthroline hydrate is probably combustible.

Biochem/physiol Actions

Metalloprotease inhibitor; chelates iron, zinc and other divalent metals. Effective concentration 1-10 mM.

Purification Methods

Crystallise its picrate (m 191o) from EtOH; then the free base is liberated with aqueous alkali, dried at 78o/8mm over P2O5 and crystallised from pet ether (b 80-100o). [Cumper et al. J Chem Soc 1188 1962.] It can be purified by zone melting. It has also been crystallised from hexane, *benzene/pet ether (b 40-60o) or sodium-dried *benzene, dried and stored over H2SO4. The monohydrate is obtained by crystallisation from aqueous EtOH or ethyl acetate. It has been crystallised from H2O (300 parts) to give the monohydrate m 102-103o which sublimes at 10-3mm [Fielding & LeFevre J Chem Soc 1811 1951.] The anhydrous compound has m 118o (after drying at high vacuum at 80o) and is also obtained by recrystallisation from pet ether or *C6H6 (70 parts) and drying at 78o/8mm. [UV: Badger et al. J Chem Soc 3199 1951.] IthasapKainH2Oof 4.857 (25o) or 5.02 (20o) and 4.27 in 50% aqueous EtOH (20o). [Albert et al. J Chem Soc 2240 1948]. [Beilstein 23 H 227, 23 II 235, 23/8 V 419.]

1,10-Phenanthroline hydrate Preparation Products And Raw materials

Global( 566)Suppliers
Supplier Tel Email Country ProdList Advantage
Shenyang Simchoice Chemical Co.,Ltd
+86-024-23769576 +86-15040101888 sales@simchoicechem.com China 254 58
Tangshan Moneide Trading Co., Ltd.
+86-315-8309571 +8615633399667 sales@moneidechem.com China 574 58
Hebei Mojin Biotechnology Co., Ltd
+86 13288715578 +8613288715578 sales@hbmojin.com China 12840 58
Shanghai UCHEM Inc.
+862156762820 +86-13564624040 sales@myuchem.com China 7514 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325 sales1@chuanghaibio.com China 5893 58
Hebei Weibang Biotechnology Co., Ltd
+8617732866630 bess@weibangbio.com China 18154 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 20287 58
Hebei Zhuanglai Chemical Trading Co.,Ltd
+8613343047651 admin@zlchemi.com China 3002 58
Shandong Deshang Chemical Co., Ltd.
+86-0531-8875-2665 +8613153039501 info@deshangchem.com China 662 58
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
+86-15350851019 +86-15383190639 admin@86-ss.com China 1000 58

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View Lastest Price from 1,10-Phenanthroline hydrate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1,10-Phenanthroline hydrate pictures 2024-11-23 1,10-Phenanthroline hydrate
5144-89-8
US $999.00-666.00 / ton 1ton 99% 5000 HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
O-Phenanthroline Monohydrate pictures 2024-11-22 O-Phenanthroline Monohydrate
5144-89-8
US $180.00 / kg 1kg 99% 20ton Hebei Zhuanglai Chemical Trading Co.,Ltd
o-Phenanthroline monohydrate pictures 2024-11-17 o-Phenanthroline monohydrate
5144-89-8
US $48.00 / mg 98.73% 10g TargetMol Chemicals Inc.

1,10-Phenanthroline hydrate Spectrum

1,10-PHENANTHROLINE MONOHYDRATE (O-) ORTHOPHENANTHROLINE MONOHYDRATE O-PHENANTHROLINE HYDRATE 1,10-phenanthrollne,monohydrate 4,5-Phenanthrolinemonohydrate 1 10-PHENANTHROLINE MONOHYDRATE 99% & 1,10-PHENANTHROLINE MONOHYDRATE*ACS REAG ENT 1,10-PHENANTHROLINE MONOHYDRATE, 99%, A. C.S. REAGENT 1,10-Phenanthroline(Monohydrate)Gr 1,10-PhenanthrolineGrMonohydrate-RedoxIndicator 1,10-PhenanthrolineGrMonohydrate 1,10-PHENANTHROLINE MONOHYDRATE, 99+% Black bone vine extract HISTOLOGICAL FIXATIVE A.F.A. HISTONORM 1,10-Phenanthroline monohydrate ACS reagent, puriss. p.a., >=99.5% (calc. to the dried substance), for redox titration 1,10-Phenanthroline monohydrate Vetec(TM) reagent grade 1,10-PHENANTHROLINE 1H2O Phenanthroline analytical grade EGG YOLK (6X100ML)+TELLUR.(6X) Y-IRR. 1,10-Phenanthroline monohydrate, reagent ACS 1,10-Phenanthrolinemonhydrate 1,10-Phenanthroline monohydrate, ACS 1,10-PHENANTHROLINE MONOHYDRATE extrapure AR 1,10-Phenanthroline, Monohydrate, Reagent 1,10-Phenanthroline Monohydrate [for Biochemical Research] 1,10-PHENANTHROLINE AR 1,10-PHENANTHROLINE AR (H2O) 1,10-phenanthrolinemonorate 1,10-Phenanthroline hydrate,99+% 1,10-Phenanthroline Monohydrate,98% o-Phenanthroline monohydrate, redox indicator, reagent grade, ACS 1,10-Phenanthroline monohydrate p.a. o-Phenanthroline Monohydrate, GR ACS 1,10-Phenanthroline  1,10-Phenanthroline Monohydrate, 99+% 25GR 1,10-Phenanthroline Monohydrate, 99+% 5GR glaucescent fissistigma root P.E. 1,10-Phenanthroline monohydrate≥ 99.5% (Titration) 1,10-PHENANTHROLINE HYDRATE 1,10-PhenanthrolineMonohydrate[forBiochemicalResearch]> 1,10-Phenanthroline monohydrate, 98%, for analysis 1,10-Phenanthroline monohydrate, 99%, for bio 1,10-Phenanthroline monohydrate, 99%, reagent grade 1,10-PhenanthrolineMonohydrate> 1,10-Phenanthroline monohydrat,≥98% 1,10-Phenanthroline hydrate USP/EP/BP 1,10-Phenanthroline 1-hydrate 1,10-Phenanthroline monohydrate, indicator, AR reagent 1,10-Phenanthroline monohydrate AR 99% 1,10-Phenanthroline, GR 99%+ 5144-89-8 1,10-Phenanthroline hydrate 1,10-Phenanthroline Monohydrate extrapure AR, 99.5% 1,10-Phenanthroline Monohydrate extrapure AR, ACS, ExiPlus, Multi-Compendial, 99.5% 1,10 PHENANTHROLINE MONOHYDRATE AR/ACS 1,10- phenanthroline ferrous indicator O-phenanthroline indicator solution 1,10-Phenanthroline hydrate solution 1,10-Phenanthroline monohydrate, 99%, indicator, ACS reagent