1,10-Phenanthroline hydrate
- CAS No.
- 5144-89-8
- Chemical Name:
- 1,10-Phenanthroline hydrate
- Synonyms
- 1,10-PHENANTHROLINE MONOHYDRATE;ORTHO-PHENANTHROLINE;Phenanthroline Monohydrate;1,10-PHENANTHROLINE H2O;O-PHENANTHROLINE MONOHYDRATE;10-Phenanthroline monohydrate;1,10-Phenanthroline, ACS, 99%;PHENYLANTHROLINE HYDRATE 1,10-;1,10-PHENANTHROLINE AR;Black bone vine extract
- CBNumber:
- CB8290304
- Molecular Formula:
- C12H8N2.H2O
- Molecular Weight:
- 198.22
- MDL Number:
- MFCD00149973
- MOL File:
- 5144-89-8.mol
- MSDS File:
- SDS
Melting point | 100-104 °C(lit.) |
---|---|
Density | 1.10 |
vapor density | 6.2 (vs air) |
storage temp. | Sealed in dry,Room Temperature |
solubility | methanol: soluble200MM (Stock solution is stable for months at –20° C.) |
form | Needle-Like Crystals |
color | Off-white, may become cream-colored during storage |
Water Solubility | <0.01 g/100 mL at 21 ºC |
Merck | 14,7214 |
BRN | 4008096 |
Stability | Stable. Incompatible with iron, other heavy metals, strong oxidizing agents, strong acids. |
CAS DataBase Reference | 5144-89-8(CAS DataBase Reference) |
FDA UNII | KSX215X00E |
EPA Substance Registry System | 1,10-Phenanthroline, monohydrate (5144-89-8) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS06,GHS09 |
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Signal word | Danger | |||||||||
Hazard statements | H301-H410 | |||||||||
Precautionary statements | P273-P301+P310+P330 | |||||||||
Hazard Codes | T,N | |||||||||
Risk Statements | 25-50/53 | |||||||||
Safety Statements | 45-60-61 | |||||||||
RIDADR | UN 2811 6.1/PG 3 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | SF8437000 | |||||||||
TSCA | Yes | |||||||||
HazardClass | 6.1 | |||||||||
PackingGroup | III | |||||||||
HS Code | 29339990 | |||||||||
Toxicity | LD50 orally in Rabbit: 132 mg/kg | |||||||||
NFPA 704 |
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1,10-Phenanthroline hydrate price More Price(72)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 77500 | 1,10-Phenanthroline monohydrate for the spectrophotometric determination of Fe, Pd, V, ≥99.0% | 5144-89-8 | 5G | $61.4 | 2024-03-01 | Buy |
Sigma-Aldrich | 77500 | 1,10-Phenanthroline monohydrate for the spectrophotometric determination of Fe, Pd, V, ≥99.0% | 5144-89-8 | 25g | $242 | 2024-03-01 | Buy |
Sigma-Aldrich | 320056 | 1,10-Phenanthroline monohydrate ACS reagent, 99% | 5144-89-8 | 5g | $70.8 | 2024-03-01 | Buy |
Sigma-Aldrich | 320056 | 1,10-Phenanthroline monohydrate ACS reagent, 99% | 5144-89-8 | 25g | $209 | 2024-03-01 | Buy |
Sigma-Aldrich | 1.07225 | 1,10-Phenanthroline monohydrate GR ACS | 5144-89-8 | 10g | $242 | 2024-03-01 | Buy |
1,10-Phenanthroline hydrate Chemical Properties,Uses,Production
Chemical Properties
white crystals or powder
Uses
When complexed with copper, it possesses nuclease activity that has been used to study DNA-protein interactions.
1,10-Phenanthroline monohydrate is an aromatic nitrogen heterocycle that may be used as a chelating agent in the preparation of metal-chelate complexes.
Uses
1,10-Phenanthroline monohydrate is useful to study the DNA-protein interactions due to its nuclease activity. It is used as a redox indicator and reagent for spectrophotometric assay of silver. It acts as a chelating ligand for the determination of Fe, Pd and V. It also acts as a matrix metalloproteinase inhibitor. It is a photometric reagent for iron, which forms a red chelate with ferrous (iron II) ion.
General Description
White crystalline powder or solid. Slight odor.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
1,10-Phenanthroline hydrate is incompatible with strong oxidizers. 1,10-Phenanthroline hydrate is also incompatible with strong acids. 1,10-Phenanthroline hydrate forms complex compounds with ferrous ions. .
Fire Hazard
Flash point data for 1,10-Phenanthroline hydrate are not available. 1,10-Phenanthroline hydrate is probably combustible.
Biochem/physiol Actions
Metalloprotease inhibitor; chelates iron, zinc and other divalent metals. Effective concentration 1-10 mM.
Purification Methods
Crystallise its picrate (m 191o) from EtOH; then the free base is liberated with aqueous alkali, dried at 78o/8mm over P2O5 and crystallised from pet ether (b 80-100o). [Cumper et al. J Chem Soc 1188 1962.] It can be purified by zone melting. It has also been crystallised from hexane, *benzene/pet ether (b 40-60o) or sodium-dried *benzene, dried and stored over H2SO4. The monohydrate is obtained by crystallisation from aqueous EtOH or ethyl acetate. It has been crystallised from H2O (300 parts) to give the monohydrate m 102-103o which sublimes at 10-3mm [Fielding & LeFevre J Chem Soc 1811 1951.] The anhydrous compound has m 118o (after drying at high vacuum at 80o) and is also obtained by recrystallisation from pet ether or *C6H6 (70 parts) and drying at 78o/8mm. [UV: Badger et al. J Chem Soc 3199 1951.] IthasapKainH2Oof 4.857 (25o) or 5.02 (20o) and 4.27 in 50% aqueous EtOH (20o). [Albert et al. J Chem Soc 2240 1948]. [Beilstein 23 H 227, 23 II 235, 23/8 V 419.]
1,10-Phenanthroline hydrate Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shenyang Simchoice Chemical Co.,Ltd | +86-024-23769576 +86-15040101888 | sales@simchoicechem.com | China | 254 | 58 |
Tangshan Moneide Trading Co., Ltd. | +86-315-8309571 +8615633399667 | sales@moneidechem.com | China | 574 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12837 | 58 |
Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 7433 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5893 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20288 | 58 |
Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3002 | 58 |
Shandong Deshang Chemical Co., Ltd. | +86-0531-8875-2665 +8613153039501 | info@deshangchem.com | China | 660 | 58 |
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | +86-15350851019 +86-15383190639 | admin@86-ss.com | China | 1000 | 58 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18648 | 58 |
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View Lastest Price from 1,10-Phenanthroline hydrate manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-11-03 | 1,10-Phenanthroline hydrate
5144-89-8
|
US $999.00-666.00 / ton | 1ton | 99% | 5000 | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | ||
2024-11-02 | o-Phenanthroline monohydrate
5144-89-8
|
US $30.00-64.00 / mg | 98.73% | 10g | TargetMol Chemicals Inc. | |||
2024-11-01 | O-Phenanthroline Monohydrate
5144-89-8
|
US $180.00 / kg | 1kg | 99% | 20ton | Hebei Zhuanglai Chemical Trading Co.,Ltd |
- 1,10-Phenanthroline hydrate
5144-89-8
- US $999.00-666.00 / ton
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
- o-Phenanthroline monohydrate
5144-89-8
- US $30.00-64.00 / mg
- 98.73%
- TargetMol Chemicals Inc.
- O-Phenanthroline Monohydrate
5144-89-8
- US $180.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd
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