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Decapeptide-12

Decapeptide-12 structure

CAS No.: 137665-91-9

Chemical Name:: Decapeptide-12

Synonyms: Decapeptide-12;Decapeptide-12/ Lumixyl;Decapeptide-12 USP/EP/BP;Decapeptide-12 lumixyl / cosmetic peptide;H-Tyr-Arg-Ser-Arg-Lys-Tyr-Ser-Ser-Trp-Tyr-OH;L-Tyrosine, L-tyrosyl-L-arginyl-L-seryl-L-arginyl-L-lysyl-L-tyrosyl-L-seryl-L-seryl-L-tryptophyl-

CBNumber:: CB83128840

Molecular Formula:: C65H90N18O17

Molecular Weight:: 1395.52

MDL Number:: MFCD00273671

MOL File:: 137665-91-9.mol

Last updated:2025-04-18 09:52:55

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Decapeptide-12 Properties

Density	1.51±0.1 g/cm3(Predicted)
pka	3.07±0.10(Predicted)
Sequence	H-Tyr-Arg-Ser-Arg-Lys-Tyr-Ser-Ser-Trp-Tyr-OH

Decapeptide-12 Chemical Properties,Uses,Production

Description

Decapeptide-12 is an oligopeptide that is made up of just 10 amino acids. This oligopeptide is known for its anti-tyrosinase activity. Tyrosinase is accountable for producing melanin in the skin. Decapeptide 12 connects to tyrosinase and prevents it from catalyzing the oxidation of phenols – the initial step in melanin creation. It’s able to interfere with tyrosinase and lighten skin.

Uses

Decapeptide-12, a small oligopeptide, is a tyrosinase inhibitor that interacts with C-terminal residue of tyrosinase (Kd: 61.1 μM). Decapeptide-12 is a competitive inhibitor of mushroom tyrosinase (IC50: 40 μM). Decapeptide-12 also increases transcription of SIRT. Decapeptide-12 reduces melanin content in melanocytes. Decapeptide-12 is used for the research of melanogenesis, senescence, inflammation [1][2][3].

References

[1] Anan Abu Ubeid, et al. Short-sequence oligopeptides with inhibitory activity against mushroom and human tyrosinase. J Invest Dermatol. 2009 Sep;129(9):2242-9. DOI:10.1038/jid.2009.124
[2] Akihito Ochiai, et al. New tyrosinase inhibitory decapeptide: Molecular insights into the role of tyrosine residues. J Biosci Bioeng. 2016 Jun;121(6):607-613. DOI:10.1016/j.jbiosc.2015.10.010
[3] Basil M H, et al. Tyrosinase inhibitors with potent anti-senescence activity in human neonatal keratinocyte progenitors. J Dermatol Surg Res Ther, 2019, 2019: 30-39.

Decapeptide-12 Preparation Products And Raw materials

Raw materials

Preparation Products

Decapeptide-12 Suppliers

Global( 139)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Wuhan Haorong Biotechnology Co.,ltd	+86-18565342920; +8618565342920	sales@chembj.net	China	307	58
Nantong Guangyuan Chemicl Co,Ltd	+undefined17712220823	admin@guyunchem.com	China	615	58
zhuzhou dingcheng meihei comestic co.,ltd	+8618873369619	dingchengbusiness8@163.com	China	260	58
Chongqing Zhihe Biopharmaceutical Co., Ltd.	+86-18580541567 +86-17782035140	sales@zhswyy.com	China	212	58
American HealthyMorph LLC	+8613363867578	nancyyuan133@163.com	China	169	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10406	58
Cangzhou Wanyou New Material Technology Co.,Ltd	18631714998	sales@czwytech.com	CHINA	904	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
Shanghai Longyu Biotechnology Co., Ltd.	+8619521488211	info@longyupharma.com	China	2555	58

Supplier	Advantage
Wuhan Haorong Biotechnology Co.,ltd	58
Nantong Guangyuan Chemicl Co,Ltd	58
zhuzhou dingcheng meihei comestic co.,ltd	58
Chongqing Zhihe Biopharmaceutical Co., Ltd.	58
American HealthyMorph LLC	58
ATK CHEMICAL COMPANY LIMITED	60
Shenzhen Nexconn Pharmatechs Ltd	58
Cangzhou Wanyou New Material Technology Co.,Ltd	58
BOC Sciences	58
Shanghai Longyu Biotechnology Co., Ltd.	58

View Lastest Price from Decapeptide-12 manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-04-27	Decapeptide-12 137665-91-9	US $1.00 / KG	1KG	99%	10000	Wuhan Haorong Biotechnology Co.,Ltd
2025-04-20	Decapeptide-12 137665-91-9	US $0.00-0.00 / kg	0.10000000149011612kg	99%	2000kgs	Chongqing Zhihe Biopharmaceutical Co., Ltd.
2025-04-16	Decapeptide-12 137665-91-9	US $20.00 / g	1g	99%HPLC,USP Standard	10kgs	ZhenYiBio Technology Inc

Decapeptide-12
137665-91-9
US $1.00 / KG
99%
Wuhan Haorong Biotechnology Co.,Ltd

Decapeptide-12
137665-91-9
US $0.00-0.00 / kg
99%
Chongqing Zhihe Biopharmaceutical Co., Ltd.

Decapeptide-12
137665-91-9
US $20.00 / g
99%HPLC,USP Standard
ZhenYiBio Technology Inc

137665-91-9(Decapeptide-12)Related Search:

NONAPEPTIDE-1 L-Cysteine, L-cysteinylglycyl-L-glutaminyl-L-arginyl-L-α-glutamyl-L-threonyl-L-prolyl-L-α-glutamylglycyl-L-alanyl-L-α-glutamyl-L-alanyl-L-lysyl-L-prolyl-L-tryptophyl-L-tyrosyl-, cyclic (1→17)-disulfide OLIGOPEPTIDE-50 N2-(1-Oxohexadecyl)-L-lysyl-L-valyl-(2S)-2,4-diaminobutanoyl-L-threonine bis(trifluoroacetate) (salt) Dipeptide diaminobutyroyl benzylamide diacetate

histidyl-arginyl-alanyl-tryptophyl-phenylalanyl-lysinamide PALMITOYL TETRAPEPTIDE-3 Palmitoyl Hexapeptide-12 Tripeptide-1 (2S)-N2-(1-Oxohexadecyl)-L-lysyl-L-valyl-2,4-diaminobutanoic acid bis(trifluoroacetate)

N2-(1-Oxotetradecyl)-L-lysyl-L-alanyl-L-lysyl-L-alaninamide H-Ala-His-Lys-OH decapeptide-10 Decapeptide-18 Decapeptide-28

Decapeptide-23 Oligopeptide-10 OLIGOPEPTIDE-1

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Decapeptide-12 Decapeptide-12/ Lumixyl H-Tyr-Arg-Ser-Arg-Lys-Tyr-Ser-Ser-Trp-Tyr-OH Decapeptide-12 USP/EP/BP L-Tyrosine, L-tyrosyl-L-arginyl-L-seryl-L-arginyl-L-lysyl-L-tyrosyl-L-seryl-L-seryl-L-tryptophyl- Decapeptide-12 lumixyl / cosmetic peptide 137665-91-9 C65H90N18O17