BX 430
- CAS No.
- 688309-70-8
- Chemical Name:
- BX 430
- Synonyms
- BX 430;BX430, 10 mM in DMSO;1-(2,6-Dibromo-4-isopropylphenyl)-3-(pyridin-3-yl)urea;N-[2,6-Dibromo-4-(1-methylethyl)phenyl]-N'-(3-pyridinyl)urea;Urea, N-[2,6-dibromo-4-(1-methylethyl)phenyl]-N'-3-pyridinyl-;P2X Receptor,Ca channels,BX430,chronic,channels,species,P2XRs,Inhibitor,disease,Ca2+ channels,BX 430,cardiovascular,P2X4,receptor,specificity,inhibit,Calcium Channel,human,pain,BX-430
- CBNumber:
- CB83146266
- Molecular Formula:
- C15H15Br2N3O
- Molecular Weight:
- 413.11
- MDL Number:
- MFCD02678819
- MOL File:
- 688309-70-8.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
| NFPA 704 |
|
BX 430 price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Tocris | 5545 | BX430 ≥99%(HPLC) | 688309-70-8 | 10 | $169 | 2021-12-16 | Buy |
| Tocris | 5545 | BX430 ≥99%(HPLC) | 688309-70-8 | 50 | $711 | 2021-12-16 | Buy |
| TRC | B810555 | BX430 | 688309-70-8 | 10mg | $395 | 2021-12-16 | Buy |
| ChemScene | CS-0033101 | BX430 99.87% | 688309-70-8 | 50mg | $500 | 2021-12-16 | Buy |
| ChemScene | CS-0033101 | BX430 99.87% | 688309-70-8 | 5mg | $85 | 2021-12-16 | Buy |
BX 430 Chemical Properties,Uses,Production
Uses
BX 430 is a selective P2X4 allosteric antagonist in human and zebrafish.
Biological Activity
BX430 is a selective noncompetitive allosteric antagonist of human P2X4 receptor channels. P2X4 receptors are highly expressed in the CNS, and have been studied as a therapeutic target for neuropathic pain and inflammation, and treatment of traumatic brain injury, cerebral ischemia, and spinal cord injury. BX430 is highly selective for human P2X4, with minimal activity towards other P2X subtypes, including P2X1–P2X3, P2X5, and P2X7. BX430 is also an antagonist of zebrafish P2X4 but has no effect on r at and mouse P2X4 receptors. BX430 has an IC50 value of 540 nM.
IC 50
P2X4 Receptor
storage
Store at +4°C
BX 430 Preparation Products And Raw materials
Raw materials
Preparation Products
BX 430 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32222 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38642 | 58 | |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 12952 | 65 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71829 | 60 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 6345 | 55 |
| Shanghai Chaolan Chemical Technology Center | 021-QQ：65489617 15618227136 | Sales@ATKchemical.com | China | 9342 | 58 |
