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N-Me-L-Ala-maytansinol

CAS No.
77668-69-0
Chemical Name:
N-Me-L-Ala-maytansinol
Synonyms
AP3 Intermidate;AP3 Intermidate 1;N-Me-L-Ala-maytansinol;Maytansine, N2'-deacetyl-;maytansinol 3-(S)-α-N-methylaminopropionate;Benzoicacid,4-fluoro-,(5-bromo-4-methoxyphenyl)methylester;(1S,2R,3S,5S,6R,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.11?,1?.03,?]hexacosa-10,12,14(26),16,18-pentaen-6-yl (2S)-2-(methylamino)propanoate
CBNumber:
CB83147258
Molecular Formula:
C32H44ClN3O9
Molecular Weight:
650.17
MDL Number:
MFCD32263382
MOL File:
77668-69-0.mol
Last updated:2024-10-28 16:48:35

N-Me-L-Ala-maytansinol Properties

Boiling point 849.5±65.0 °C(Predicted)
Density 1.31±0.1 g/cm3(Predicted)
pka 9.82±0.70(Predicted)
form Solid
color White to off-white

N-Me-L-Ala-maytansinol Chemical Properties,Uses,Production

Description

Maytansinoid-Ala is a potent microtubule-targeted compound that inhibits proliferation of cells at mitosis. Maytansinoid-Ala can be used for synthesis of ADCs. The microtubule-targeting maytansinoids accumulate in cells and induce mitotic arrest at 250- to 1000-fold lower concentrations than those required for their association with tubulin or microtubules.

N-Me-L-Ala-maytansinol Preparation Products And Raw materials

Raw materials

Preparation Products

N-Me-L-Ala-maytansinol Suppliers

Global( 41)Suppliers
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Shenzhen Nexconn Pharmatechs Ltd
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TargetMol Chemicals Inc.
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Jilin Chinese Academy of Sciences-yanshen Technology
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View Lastest Price from N-Me-L-Ala-maytansinol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-Me-L-Ala-maytansinol pictures 2024-10-28 N-Me-L-Ala-maytansinol
77668-69-0
US $61.00-239.00 / mg 10g TargetMol Chemicals Inc.
N-Me-L-Ala-maytansinol pictures 2023-05-25 N-Me-L-Ala-maytansinol
77668-69-0
US $0.00 / G 5G 98% 1KG Jiangsu Nata Opto-electronic Material Co.,Ltd.

77668-69-0(N-Me-L-Ala-maytansinol)Related Search:

N-Me-L-Ala-maytansinol AP3 Intermidate 1 maytansinol 3-(S)-α-N-methylaminopropionate AP3 Intermidate Maytansine, N2'-deacetyl- Benzoicacid,4-fluoro-,(5-bromo-4-methoxyphenyl)methylester (1S,2R,3S,5S,6R,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.11?,1?.03,?]hexacosa-10,12,14(26),16,18-pentaen-6-yl (2S)-2-(methylamino)propanoate 77668-69-0 C32H44ClN3O9