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Hoechst 33258

CAS No.
23491-45-4
Chemical Name:
Hoechst 33258
Synonyms
BBIH;BXI-72;H33258;abs9129;Ht-33258;hoe33058;NSC334072;HOE 33258;nsc-322921;33258hoechst
CBNumber:
CB8329486
Molecular Formula:
C25H25ClN6O
Molecular Weight:
460.97
MDL Number:
MFCD00012679
MOL File:
23491-45-4.mol
MSDS File:
SDS
Last updated:2024-11-19 23:02:33

Hoechst 33258 Properties

Melting point 314 °C
Density 1.5099 (rough estimate)
refractive index 1.6300 (estimate)
storage temp. -20°C
solubility H2O: 10 mg/mL
form powder
color Yellow to Very Dark Yellow
Water Solubility SOLUBLE
BRN 4088183
Stability Hygroscopic
CAS DataBase Reference 23491-45-4(CAS DataBase Reference)
FDA UNII MHT095273M
EPA Substance Registry System Phenol, 4-[5-(4-methyl-1-piperazinyl)[2,5'-bi-1H-benzimidazol]-2'-yl]-, trihydrochloride (23491-45-4)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P305+P351+P338
Hazard Codes  Xn
Risk Statements  22-36/38-36/37/38-20/21/22
Safety Statements  26-36-24/25-23
WGK Germany  3
RTECS  SM1140500
3-8-10
HS Code  32129000
Toxicity dog,LD,intravenous,> 22400ug/kg (22.4mg/kg),LUNGS, THORAX, OR RESPIRATION: DYSPNEASENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYEGASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS,National Technical Information Service. Vol. PB84-171206,
NFPA 704
0
2 0

Hoechst 33258 price More Price(41)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 382061 Bisbenzimide H 33258 Fluorochrome, Trihydrochloride - CAS 23491-45-4 - Calbiochem Membrane-permeable, adenine-thymine-specific fluorescent stain. 23491-45-4 1g $962 2024-03-01 Buy
Sigma-Aldrich 14530 bisBenzimide H 33258 for fluorescence, ≥98.0% (HPLC) 23491-45-4 100mg $105 2024-03-01 Buy
Sigma-Aldrich 14530 bisBenzimide H 33258 for fluorescence, ≥98.0% (HPLC) 23491-45-4 500mg $372 2024-03-01 Buy
TCI Chemical H1343 2'-(4-Hydroxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5'-bibenzimidazole Trihydrochloride Hydrate[for Biochemical Research] >98.0%(HPLC) 23491-45-4 25mg $65 2024-03-01 Buy
Cayman Chemical 16756 Hoechst 33258 ≥95% 23491-45-4 50mg $47 2024-03-01 Buy
Product number Packaging Price Buy
382061 1g $962 Buy
14530 100mg $105 Buy
14530 500mg $372 Buy
H1343 25mg $65 Buy
16756 50mg $47 Buy

Hoechst 33258 Chemical Properties,Uses,Production

Chemical Properties

yellow to yellow-green powder

Uses

bisBenzimide H 33258 is useful for staining DNA, chromosomes and nuclei. bisBenzimide H 33258 may be used for fluorescence microscopy or flow cytometry.
Excitation max. =?346 nm
Emission max. =?460 nm

Uses

Hoechst 33258 is a Hoechst stain used to stain DNA. It is part of a family of fluorescent dyes. Dyes and metabolites.

Uses

Hoechst 33258 is useful for staining DNA, chromosomes and nuclei. The nucleic acid binds to the minor groove of DNA at AT-rich sequences. This dye is commonly used for determining the DNA content of viable cells without detergent treatment or fixation and for fluorescence

General Description

Membrane-permeable, adenine-thymine-specific fluorescent stain. Useful for staining DNA, chromosomes, and nuclei. Increases the rate of channel-mediated Ca2+ efflux from junctional cytoplasmic reticulum vesicles. Can also be used to detect mycoplasma contamination in tissue culture. H 33258 and the related compound H 33342 (Cat. No. 382065) have been used in conjunction with RNA aptamers in the 5′ untranslated region (UTR) to control expression of transfected gene constructs.

Biochem/physiol Actions

bisBenzimide H 33258 is a potent and selective Bcl-XL inhibitor. bisBenzimide H 33258 is a membrane-permeable, fluorescent DNA stain with low cytotoxicity that intercalate in A-T regions of DNA.

storage

+4°C (desiccate)

Hoechst 33258 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 224)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd
+86 13288715578 +8613288715578 sales@hbmojin.com China 12839 58
Hangzhou FandaChem Co.,Ltd.
+8615858145714 FandaChem@Gmail.com China 9206 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32957 60
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29881 58
Chongqing Chemdad Co., Ltd
+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49374 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32165 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626 eric@witopchemical.com China 23541 58
Hefei Hirisun Pharmatech Co., Ltd
+8615056975894 shawn@hirisunpharm.com CHINA 9911 58

View Lastest Price from Hoechst 33258 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Hoechst 33258 trihydrochloride pictures 2024-11-19 Hoechst 33258 trihydrochloride
23491-45-4
US $53.00-42.00 / mg 96.31% 10g TargetMol Chemicals Inc.
Hoechst 33258 pictures 2023-09-28 Hoechst 33258
23491-45-4
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
Hoechst 33258 pictures 2019-07-14 Hoechst 33258
23491-45-4
US $1.00 / KG 1KG 99% 25kg Career Henan Chemical Co
  • Hoechst 33258 pictures
  • Hoechst 33258
    23491-45-4
  • US $0.00 / KG
  • 99%
  • Hebei Mojin Biotechnology Co., Ltd
Bis-BenzimideFluorochrome p-(5-(5-(4-Methyl-1-piperazinyl)-1H-2-benzimidazolyl)-1H-2-benzimidazolyl)phenol trihydrochloride Hoechst(R) 33258,98% bisBenzimide, 2μ-(4-hydroxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5μ-bi-1H-benzimidazole hydrate trihydrochloride HOE 33258, Hoechst 33258, 2μ-(4-Hydroxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5μ-bi(1H-benzimidazole) trihydrochloride, 2-[2-(4-Hydroxyphenyl)-6-benzimidazoyl]-6-(1-methyl-4-piperazyl)benzimidazole trihydrochloride 4-[5-[6-(4-Methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1,3-dihydrobenzimidazol-2-ylidene]cyclohexa-2,5-dien-1-one trihydrochloride Phenol, p-(5-(5-(4-methyl-1-piperazinyl)-2-benzimidazolyl)-2-benzimidazolyl)-, trihydrochloride Pibenzimol HCl Ht-33258 Bisbenzimide H33258 p-(5-(5-(4-Methyl-1-pip bisBenzimide H 33258,2′-(4-Hydroxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5′-bi(1H-benzimidazole) trihydrochloride, 2-[2-(4-Hydroxyphenyl)-6-benzimidazoyl]-6-(1-methyl-4-piperazyl)benzimidazole trihydroc Bis Benzimide Hoechst H 33258 BBIH 2'-(4-Hydroxyphenyl)-5-(4-Methyl-1-piperazinyl)-2,5'-bibenziMidazole Trihydrochloride 2'-(4-Hydroxyphenyl)-5-(4-Methyl-1-piperazinyl)-2,5'-bibenziMidazole Trihydrochloride Hydrate [for BiocheMical Research] Hearst fluorescence fuels, 33258 33258hoechst 4-(5-(4-methyl-1-piperazinyl)(2,5’-bi-1h-benzimidazol)-2’-yl)-phenotrihy 4-[5-(4-methyl-1-piperazinyl)[2,5’-bi-1h-benzimidazol]-2’-yl]-phenotrihydr bisbenzimidazoletrihydrochloride bisbenzimidehydrochloride BISBENZIMIDE H 33258 FLUOROCHROME BISBENZIMIDE H 33258 FLUOROCHROME PACKAG BISBENZIMIDE H 33258, FOR FLUORESCENCE HOECHST 33258,98% BXI-72 NSC334072 Hoechst 33258 solution Bisbenzimide H33258 Fluorochrome Trihydrochloride 〔HOE 33258〕 Bisbenzimide H33258 Fluorochrome Trihydrochloride DMSO Solution (1mg/ml) Bisbenzimide (Hoechst 33258) Hoechst 33258 (trihydrochloride) hoe33058 hoechstdye33258 nsc-322921 HOE 33258 HOECHST NO 33258 HOECHST STAIN SOLUTION HOECHST 33258 H33258 BISBENZIMIDE TRIHYDROCHLORIDE BISBENZIMIDE H 33258 BISBENZIMIDE H 33258 FLUOROCHROME, TRIHYDROCHLORIDE BISBENZIMIDE H 33258 TRIHYDROCHLORIDE BISBENZIMIDE 2'-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI(1H-BENZIMIDAZOLE) TRIHYDROCHLORIDE 2-[2-(4-HYDROXYPHENYL)-6-BENZIMIDAZOLYL]-6-(1-METHYL-4-PIPERAZYL)-BENZIMIDAZOLE TRIHYDROCHLORIDE 2-[-2-(4-HYDROXYPHENYL)-6-BENZIMIDAZOYL]-6-(1-METHYL-4-PIPERAZYL)-BENZIMIDAZOLE, 3HCL 2-[2-(4-HYDROXYPHENYL)-6-BENZIMIDAZOYL]-6-(1-METHYL-4-PIPERAZYL)BENZIMIDAZOLE TRIHYDROCHLORIDE p-[5-(4-methyl-1-piperazinyl)[2,5'-bi-1H-benzimidazol]-2'-yl]phenol trihydrochloride BISBENZIMIDE HOECHST NO 33258TRIHYDROCHL ORIDE Pibenzimol hydrochloride Hydroxyphenyl Research 4-[6-(4-Methyl-1-piperazinyl)[2,6'-bi-1H-benzimidazol]-2'-yl]phenol trihydrochloride Bisbenzimide H 33258 Fluorochrome, Trihydrochloride - CAS 23491-45-4 - Calbiochem Hoechst 33258 *CAS 23491-45-4* Hoechst 33258 solution, 1mg/mL in H2O