Hoechst 33258
- CAS No.
- 23491-45-4
- Chemical Name:
- Hoechst 33258
- Synonyms
- BBIH;BXI-72;H33258;abs9129;Ht-33258;hoe33058;NSC334072;HOE 33258;nsc-322921;33258hoechst
- CBNumber:
- CB8329486
- Molecular Formula:
- C25H25ClN6O
- Molecular Weight:
- 460.97
- MDL Number:
- MFCD00012679
- MOL File:
- 23491-45-4.mol
- MSDS File:
- SDS
Melting point | 314 °C |
---|---|
Density | 1.5099 (rough estimate) |
refractive index | 1.6300 (estimate) |
storage temp. | -20°C |
solubility | H2O: 10 mg/mL |
form | powder |
color | Yellow to Very Dark Yellow |
Water Solubility | SOLUBLE |
BRN | 4088183 |
Stability | Hygroscopic |
CAS DataBase Reference | 23491-45-4(CAS DataBase Reference) |
FDA UNII | MHT095273M |
EPA Substance Registry System | Phenol, 4-[5-(4-methyl-1-piperazinyl)[2,5'-bi-1H-benzimidazol]-2'-yl]-, trihydrochloride (23491-45-4) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H302-H315-H319 | |||||||||
Precautionary statements | P305+P351+P338 | |||||||||
Hazard Codes | Xn | |||||||||
Risk Statements | 22-36/38-36/37/38-20/21/22 | |||||||||
Safety Statements | 26-36-24/25-23 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | SM1140500 | |||||||||
F | 3-8-10 | |||||||||
HS Code | 32129000 | |||||||||
Toxicity | dog,LD,intravenous,> 22400ug/kg (22.4mg/kg),LUNGS, THORAX, OR RESPIRATION: DYSPNEASENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYEGASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS,National Technical Information Service. Vol. PB84-171206, | |||||||||
NFPA 704 |
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Hoechst 33258 price More Price(41)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 382061 | Bisbenzimide H 33258 Fluorochrome, Trihydrochloride - CAS 23491-45-4 - Calbiochem Membrane-permeable, adenine-thymine-specific fluorescent stain. | 23491-45-4 | 1g | $962 | 2024-03-01 | Buy |
Sigma-Aldrich | 14530 | bisBenzimide H 33258 for fluorescence, ≥98.0% (HPLC) | 23491-45-4 | 100mg | $105 | 2024-03-01 | Buy |
Sigma-Aldrich | 14530 | bisBenzimide H 33258 for fluorescence, ≥98.0% (HPLC) | 23491-45-4 | 500mg | $372 | 2024-03-01 | Buy |
TCI Chemical | H1343 | 2'-(4-Hydroxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5'-bibenzimidazole Trihydrochloride Hydrate[for Biochemical Research] >98.0%(HPLC) | 23491-45-4 | 25mg | $65 | 2024-03-01 | Buy |
Cayman Chemical | 16756 | Hoechst 33258 ≥95% | 23491-45-4 | 50mg | $47 | 2024-03-01 | Buy |
Hoechst 33258 Chemical Properties,Uses,Production
Chemical Properties
yellow to yellow-green powder
Uses
bisBenzimide H 33258 is useful for staining DNA, chromosomes and nuclei. bisBenzimide H 33258 may be used for fluorescence microscopy or flow cytometry.
Excitation max. =?346 nm
Emission max. =?460 nm
Uses
Hoechst 33258 is a Hoechst stain used to stain DNA. It is part of a family of fluorescent dyes. Dyes and metabolites.
Uses
Hoechst 33258 is useful for staining DNA, chromosomes and nuclei. The nucleic acid binds to the minor groove of DNA at AT-rich sequences. This dye is commonly used for determining the DNA content of viable cells without detergent treatment or fixation and for fluorescence
General Description
Membrane-permeable, adenine-thymine-specific fluorescent stain. Useful for staining DNA, chromosomes, and nuclei. Increases the rate of channel-mediated Ca2+ efflux from junctional cytoplasmic reticulum vesicles. Can also be used to detect mycoplasma contamination in tissue culture. H 33258 and the related compound H 33342 (Cat. No. 382065) have been used in conjunction with RNA aptamers in the 5′ untranslated region (UTR) to control expression of transfected gene constructs.
Biochem/physiol Actions
bisBenzimide H 33258 is a potent and selective Bcl-XL inhibitor. bisBenzimide H 33258 is a membrane-permeable, fluorescent DNA stain with low cytotoxicity that intercalate in A-T regions of DNA.
storage
+4°C (desiccate)
Hoechst 33258 Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12839 | 58 |
Hangzhou FandaChem Co.,Ltd. | +8615858145714 | FandaChem@Gmail.com | China | 9206 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29881 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32165 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
View Lastest Price from Hoechst 33258 manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-11-19 | Hoechst 33258 trihydrochloride
23491-45-4
|
US $53.00-42.00 / mg | 96.31% | 10g | TargetMol Chemicals Inc. | |||
2023-09-28 | Hoechst 33258
23491-45-4
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | ||
2019-07-14 | Hoechst 33258
23491-45-4
|
US $1.00 / KG | 1KG | 99% | 25kg | Career Henan Chemical Co |
- Hoechst 33258 trihydrochloride
23491-45-4
- US $53.00-42.00 / mg
- 96.31%
- TargetMol Chemicals Inc.
- Hoechst 33258
23491-45-4
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
- Hoechst 33258
23491-45-4
- US $1.00 / KG
- 99%
- Career Henan Chemical Co