Dicyclopropyl ketone
- CAS No.
- 1121-37-5
- Chemical Name:
- Dicyclopropyl ketone
- Synonyms
- DICYCLOPROPYLMETHANONE;CYCLOPROPYL KETONE;DICYCLOPROPYL KETONE;DicyclopropylKetone>DICYCLOPROPYLMETHYLOXIME;Dicyclopropyl ketone,95%;Methanone,dicyclopropyl-;Dicyclopropylmethanone 96%;Dicyclopropyl Ketone, 97+%;Dicyclopropyl-methanoneNSC
- CBNumber:
- CB8331519
- Molecular Formula:
- C7H10O
- Molecular Weight:
- 110.15
- MDL Number:
- MFCD00001276
- MOL File:
- 1121-37-5.mol
| Melting point | 44.0-44.5 °C |
|---|---|
| Boiling point | 160-162 °C(lit.) |
| Density | 0.977 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 103 °F |
| storage temp. | Store below +30°C. |
| Specific Gravity | 0.957 |
| Water Solubility | Soluble in water. |
| BRN | 774172 |
| InChI | InChI=1S/C7H10O/c8-7(5-1-2-5)6-3-4-6/h5-6H,1-4H2 |
| InChIKey | BIPUHAHGLJKIPK-UHFFFAOYSA-N |
| SMILES | C(C1CC1)(C1CC1)=O |
| CAS DataBase Reference | 1121-37-5(CAS DataBase Reference) |
| FDA UNII | FGQ92KB360 |
| NIST Chemistry Reference | Methanone, dicyclopropyl-(1121-37-5) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS02 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H226 | |||||||||
| Precautionary statements | P210-P233-P240-P241-P242-P243 | |||||||||
| Hazard Codes | F,Xn | |||||||||
| Risk Statements | 10-36/37/38-20/21/22-5 | |||||||||
| Safety Statements | 16-36-26-3 | |||||||||
| RIDADR | UN 1224 3/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Harmful/Flammable | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29142900 | |||||||||
| NFPA 704 |
|
Dicyclopropyl ketone price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.40157 | Dicyclopropylketone for synthesis | 1121-37-5 | 25ML | $80.8 | 2024-03-01 | Buy |
| TCI Chemical | D1758 | Dicyclopropyl Ketone >95.0%(GC) | 1121-37-5 | 25mL | $41 | 2024-03-01 | Buy |
| Alfa Aesar | A11580 | Dicyclopropyl ketone, 96% | 1121-37-5 | 25g | $41 | 2021-12-16 | Buy |
| Alfa Aesar | A11580 | Dicyclopropyl ketone, 96% | 1121-37-5 | 100g | $146 | 2021-12-16 | Buy |
| TRC | D439305 | Dicyclopropyl Ketone | 1121-37-5 | 50g | $140 | 2021-12-16 | Buy |
Dicyclopropyl ketone Chemical Properties,Uses,Production
Chemical Properties
clear colourless to yellowish liquid
Uses
Dicyclopropyl Ketone is used as a reagent in the synthesis of a new class of potent and selective agonists of dimeric carbamoylguanidine-type histamine H2 receptor ligands. Also used in the preparation of chemical space analogs of PNU-282,987 and SSR180711, which have nicotinic receptor activity.
Preparation
Preparation of Dicyclopropyl ketone
Reaction: To a one liter three-necked flask fitted with a reflux condenser and a metal Hershberg stirrer there was added 600 ml. of 20% sodium hydroxide and 165g . (0.9mole) of 1,7 -dichloro-4-heptanone. The mixture was refluxed for 30 minutes with vigorous stirring, then steam distilled until the characteristic odor of dicyclopropyl ketone was absent from the distillate. The distillate was then saturated with potassium carbonate, the upper layer separated and the water layer extracted once with ether. The combined organic layers were dried over potassium carbonate. after removal of the ether there was dist illed 69g. (70%) of dicyclopropyl ketone, b.p . 69° at 20 mm, nD25 1.4648-1.4654.
References
[1] G A Olah, G Liang, G K Prakash. “The unusual Favorskii-Nazarov reaction of dicyclopropyl ketone.” Proceedings of the National Academy of Sciences of the United States of America (1976): 2945–6.
[2] Gerd Schrumpf, Thomas Alshuth. “Conformational equilibrium of dicyclopropyl ketone.” Spectrochimica acta. Part A: Molecular spectroscopy 43 7 (1987): Pages 939-942.
Dicyclopropyl ketone Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12840 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | 1022@dideu.com | China | 3882 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5893 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18777 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29882 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8811 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
View Lastest Price from Dicyclopropyl ketone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-18 | Dicyclopropyl ketone
1121-37-5
|
US $0.00-0.00 / KG | 1KG | 98% | 1000KG | Shaanxi Dideu New Materials Co. Ltd | |
 |
2024-10-11 | Dicyclopropyl ketone
1121-37-5
|
US $10.70 / kg | 10kg | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2024-07-14 | Dicyclopropyl ketone
1121-37-5
|
US $0.10 / KG | 1KG | 98.0% | 10 | Shaanxi Dideu Medichem Co. Ltd |
-
- Dicyclopropyl ketone
1121-37-5
- US $0.00-0.00 / KG
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- Dicyclopropyl ketone
1121-37-5
- US $10.70 / kg
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- Dicyclopropyl ketone
1121-37-5
- US $0.10 / KG
- 98.0%
- Shaanxi Dideu Medichem Co. Ltd