ChemicalBook >> CAS DataBase List >>RET Kinase inhibitor 1
RET Kinase inhibitor 1
- CAS No.
- 1627856-64-7
- Chemical Name:
- RET Kinase inhibitor 1
- Synonyms
- CS-2597;GSK3179106;GSK-3179106;RET Kinase inhibitor 1;c-RET inhibitor GS3179106;Benzeneacetamide, 4-(4-ethoxy-1,6-dihydro-6-oxo-3-pyridinyl)-2-fluoro-N-[5-(2,2,2-trifluoro-1,1-dimethylethyl)-3-isoxazolyl]-;syndrome,post-inflammatory,visceral,stress-induced,irritable,RET,Inhibitor,bowel,hypersensitivity,orally,GSK 3179106,inhibit,IBS,GSK3179106,GSK-3179106
- CBNumber:
- CB83356171
- Molecular Formula:
- C22H21F4N3O4
- Molecular Weight:
- 467.41
- MDL Number:
- MFCD30747847
- MOL File:
- 1627856-64-7.mol
Last updated:2024-07-02 08:55:27
Boiling point | 670.1±55.0 °C(Predicted) |
---|---|
Density | 1.37±0.1 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility |
DMSO:81.0(Max Conc. mg/mL);173.29(Max Conc. mM) DMSO:PBS (pH 7.2) (1:3):0.25(Max Conc. mg/mL);0.53(Max Conc. mM) Ethanol:15.5(Max Conc. mg/mL);33.16(Max Conc. mM) |
form | A crystalline solid |
pka | 10.30±0.10(Predicted) |
color | White to off-white |
FDA UNII | DY8BBK4G3C |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H302-H315-H319-H335 | |||||||||
Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
NFPA 704 |
|
RET Kinase inhibitor 1 price More Price(14)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 24023 | RET Kinase Inhibitor 1 | 1627856-64-7 | 1mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 24023 | RET Kinase Inhibitor 1 | 1627856-64-7 | 5mg | $139 | 2024-03-01 | Buy |
Cayman Chemical | 24023 | RET Kinase Inhibitor 1 | 1627856-64-7 | 10mg | $243 | 2024-03-01 | Buy |
Cayman Chemical | 24023 | RET Kinase Inhibitor 1 | 1627856-64-7 | 25mg | $533 | 2024-03-01 | Buy |
ChemScene | CS-7799 | GSK3179106 99.40% | 1627856-64-7 | 50mg | $800 | 2021-12-16 | Buy |
RET Kinase inhibitor 1 Chemical Properties,Uses,Production
Description
GSK3179106 is an inhibitor of rearranged during transfection (RET) kinase (IC50 = 0.4 nM). It is selective for RET kinase over VEGF receptor 2 (VEGFR2/KDR; IC50 = 109 nM). GSK3179106 reduces the number of abdominal contractions induced by colorectal distension in acetic acid-sensitized rats when administered at a dose of 10 mg/kg twice per day.
RET Kinase inhibitor 1 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 56)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32836 | 60 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10522 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
Dalian Meilun Biotech Co., Ltd. | 0411-62910999 13889544652 | meilunui@163.com | China | 4673 | 58 |
Shanghai Hope Chem Co., Ltd., | +21-18501659228 18501659228 | info@hope-chem.com | China | 477 | 55 |
1627856-64-7(RET Kinase inhibitor 1)Related Search:
RET Kinase inhibitor 1
CS-2597
c-RET inhibitor GS3179106
GSK3179106
GSK-3179106
Benzeneacetamide, 4-(4-ethoxy-1,6-dihydro-6-oxo-3-pyridinyl)-2-fluoro-N-[5-(2,2,2-trifluoro-1,1-dimethylethyl)-3-isoxazolyl]-
syndrome,post-inflammatory,visceral,stress-induced,irritable,RET,Inhibitor,bowel,hypersensitivity,orally,GSK 3179106,inhibit,IBS,GSK3179106,GSK-3179106
1627856-64-7
C22H21F4N3O4