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MK204
- CAS No.
- 1959605-73-2
- Chemical Name:
- MK204
- Synonyms
- MK204;MK204 >=98% (HPLC);Acetic acid, 2-[5-chloro-2-[[[(2,3,4,5,6-pentabromophenyl)methyl]amino]carbonyl]phenoxy]-
- CBNumber:
- CB83357936
- Molecular Formula:
- C16H9Br5ClNO4
- Molecular Weight:
- 714.22
- MDL Number:
- MFCD31382392
- MOL File:
- 1959605-73-2.mol
Last updated:2025-01-27 09:38:02
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MK204 Chemical Properties,Uses,Production
Biological Activity
MK204 is a potent and selective inhibitor of aldo-keto reductase family member 1B10 (AKR1B10). AKR1B10 is induced in several cancer types, in particular, hepatocellular carcinoma, and may be involved with drug resistance. MK204 appears to target a distinct AKR1B10 inner specificity pocket not present in the closely related aldose reductase. MK204 had an IC50 value of 80 nM compared to an IC50 value of 21.7 μM for aldose reductase.
MK204 Preparation Products And Raw materials
Raw materials
Preparation Products
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Global( 9)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
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career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29810 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19881 | 58 |
Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44807 | 58 |
Beijing Biocreative Technology Co., Ltd. | 15522676233 | 3007606172@qq.com | China | 1248 | 58 |
TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19699 | 58 |
Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | cindy.huang@synzest.com | China | 12000 | 58 |
MK204
MK204 >=98% (HPLC)
Acetic acid, 2-[5-chloro-2-[[[(2,3,4,5,6-pentabromophenyl)methyl]amino]carbonyl]phenoxy]-
1959605-73-2