ChemicalBook >> CAS DataBase List >>4-Methylsulphonylphenylacetic acid
4-Methylsulphonylphenylacetic acid
- CAS No.
- 90536-66-6
- Chemical Name:
- 4-Methylsulphonylphenylacetic acid
- Synonyms
- TIMTEC-BB SBB009970;Etoricoxib?USP RC B;Etocoxib impurity 2;4-(Methylsulfonyl)ph;Etoricoxib impurity M;OTHER BUILDING BLOCKS;Etoricoxib Impurity 28;4-MESYLPHENYLACETIC ACID;4-Mesylbenzeneacetic acid;Etoricoxib Intermediate 5
- CBNumber:
- CB8339797
- Molecular Formula:
- C9H10O4S
- Molecular Weight:
- 214.24
- MDL Number:
- MFCD00216495
- MOL File:
- 90536-66-6.mol
- MSDS File:
- SDS
Last updated:2024-08-21 22:41:43
| Melting point | 136-140 °C(lit.) |
|---|---|
| Boiling point | 324.37°C (rough estimate) |
| Density | 1.4230 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 3.90±0.10(Predicted) |
| color | White to Pale Yellow |
| Water Solubility | slight |
| BRN | 2646649 |
| CAS DataBase Reference | 90536-66-6(CAS DataBase Reference) |
| FDA UNII | C39I2W89XI |
4-Methylsulphonylphenylacetic acid price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 579114 | 4-(Methylsulfonyl)phenylacetic acid 97% | 90536-66-6 | 1g | $20 | 2023-06-20 | Buy |
| Sigma-Aldrich | 579114 | 4-(Methylsulfonyl)phenylacetic acid 97% | 90536-66-6 | 5g | $21 | 2023-06-20 | Buy |
| TCI Chemical | M1899 | 4-(Methylsulfonyl)phenylacetic Acid >98.0%(T) | 90536-66-6 | 1g | $28 | 2024-03-01 | Buy |
| TCI Chemical | M1899 | 4-(Methylsulfonyl)phenylacetic Acid >98.0%(T) | 90536-66-6 | 5g | $83 | 2024-03-01 | Buy |
| Alfa Aesar | L19504 | 4-(Methylsulfonyl)phenylacetic acid, 97% | 90536-66-6 | 5g | $51.65 | 2024-03-01 | Buy |
4-Methylsulphonylphenylacetic acid Chemical Properties,Uses,Production
Chemical Properties
yellow to beige-brown crystalline powder
Uses
4-(Methylsulfonyl)phenylacetic acid is an important raw material and intermediate used in organic synthesis, pharmaceuticals agrochemicals and dyestuff fields.
Preparation
synthesis of 4-(Methylsulfonyl)phenylacetic acid: 1-(4-Methanesulfonyl-phenyl)-ethanone (20 mmol), morpholine (60 mmol) and elemental sulfur (40 mmol) were added in a round-bottom flask and refluxed for 2 h at 398 K. A 3N solution of NaOH (20 ml) was then added, and the reaction mixture refluxed for an additional 30 min. After cooling, the mixture was filtered and the filtrate was acidified with HCl to pH 6. The solution was again filtered off and washed with ethyl acetate. The resulting aqueous fraction was finally acidified with diluted HCl, to yield the pure product as a white solid. Crystals suitable for X-ray analysis were obtained by slow evaporation of an ethanol/water (1:1 v/v) solution.
Application
4-(Methylsulfonyl)phenylacetic Acid is an intermediate used to prepare heterocyclic diaryl compounds as selective COX-2 inhibitors. It is also used to synthesize hydroxyfuranones as antioxidants and antiinflammatory agents.
4-Methylsulphonylphenylacetic acid Preparation Products And Raw materials
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View Lastest Price from 4-Methylsulphonylphenylacetic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-25 | 4-(Methylsulfonyl)phenylacetic acid
90536-66-6
|
US $1.00 / kg | 1kg | 99% | 20tons | Hebei Yanxi Chemical Co., Ltd. | |
 |
2024-10-11 | 4-Methylsulphonylphenylacetic Acid
90536-66-6
|
US $5.00-2.00 / KG | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2024-04-20 | 4-Methylsulphonylphenylacetic acid
90536-66-6
|
US $50.00 / kg | 1kg | 99.10% | 5000kg | Ouhuang Engineering Materials (Hubei) Co., Ltd |
-
- 4-(Methylsulfonyl)phenylacetic acid
90536-66-6
- US $1.00 / kg
- 99%
- Hebei Yanxi Chemical Co., Ltd.
-
- 4-Methylsulphonylphenylacetic Acid
90536-66-6
- US $5.00-2.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- 4-Methylsulphonylphenylacetic acid
90536-66-6
- US $50.00 / kg
- 99.10%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
90536-66-6(4-Methylsulphonylphenylacetic acid)Related Search:
DIMETHYL PYRIDINE-2,5-DICARBOXYLATE
Methyl 2-methylnicotinate
4-(METHYLSULFONYL)PHENYLACETONITRILE
Etoricoxib Impurity 18
4-Hydroxyphenylacetic acid
Phenethyl phenylacetate
4-Methoxyphenylacetic acid
2-Hydroxyphenylacetic acid
2-Methylphenylacetic acid
Etoricoxib
1of4
TIMTEC-BB SBB009970
4-MESYLPHENYLACETIC ACID
4-(METHANESULFONYL)PHENYLACETIC ACID
4-METHYLSULPHONYLPHENYLACETIC ACID
4-(METHYLSULFONYL)PHENYLACETIC ACID
4-methylsulfonyl benzeneacetic acid
4-(Methylsulfonyl)PhenylAceticAcid,Etoricoxib
4-Methyl Sulphonile Phenyle Acetic Acid
4-(Methanesulfonyl)phenylaceticacid,97%
4-Methylsulfonylphenylacetic
Benzeneacetic acid, 4-(methylsulfonyl)-
4-Mesylbenzeneacetic acid
4-Methylsulphonylphenylacetic acid,95%
4-(Methylsulfonyl)ph
4-(Carboxymethyl)phenyl methyl sulphone
Etoricoxib Related CoMpound B
Etoricoxib impurity M
4-(Methylsulfonyl)phenylacetic acid 97%
Etoricoxib USP Related Compound B
2-(4-methylsulfonylphenyl)acetate
Etoricoxib?USP RC B
Etoricoxib Intermediate 5
Etoricoxib Impurity 28
4-(Methylsulfonyl)phenylaceticAcid>
OTHER BUILDING BLOCKS
4-(Methylsulfonyl)phenylacetic Acid (Int of Etoricoxib)
Etocoxib impurity 2
90536-66-6
35230-23-1
C9H10O4S
H3CSO2C6H4CH2CO2H
Carboxylic acid
Carboxylic Acids
Chemical Synthesis
Organic Building Blocks
C9
Carbonyl Compounds
Carboxylic Acids
Building Blocks
Carbonyl Compounds