Isobutyramide
- CAS No.
- 563-83-7
- Chemical Name:
- Isobutyramide
- Synonyms
- IBA;Propanamide, 2-methyl-;2-methylpropanamide isobutyramide;2-Methyl-propanamide;VX 366;Butyl aMide;Isobuytramide;ISOBUTYRAMIDE;isobutyric amide;Isobutyramide>
- CBNumber:
- CB8344674
- Molecular Formula:
- C4H9NO
- Molecular Weight:
- 87.12
- MDL Number:
- MFCD00008019
- MOL File:
- 563-83-7.mol
- MSDS File:
- SDS
| Melting point | 127-131 °C (lit.) |
|---|---|
| Boiling point | 216-220 °C (lit.) |
| Density | 1.013 g/mL at 25 °C (lit.) |
| refractive index | 1.4345 (estimate) |
| Flash point | 216-220°C |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Sparingly), DMSO (Slightly) |
| form | Solid |
| pka | 16.60±0.50(Predicted) |
| color | White to Off-White |
| Water Solubility | Soluble in water. |
| LogP | 0.003 (est) |
| CAS DataBase Reference | 563-83-7(CAS DataBase Reference) |
| FDA UNII | 82UOE7B38Z |
| NIST Chemistry Reference | Propanamide, 2-methyl-(563-83-7) |
| EPA Substance Registry System | Propanamide, 2-methyl- (563-83-7) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | TX1475000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29241990 | |||||||||
| NFPA 704 |
|
Isobutyramide price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 144436 | Isobutyramide 99% | 563-83-7 | 25g | $71.4 | 2024-03-01 | Buy |
| Sigma-Aldrich | 144436 | Isobutyramide 99% | 563-83-7 | 100g | $186 | 2024-03-01 | Buy |
| TCI Chemical | I0102 | Isobutyramide >98.0%(GC) | 563-83-7 | 25g | $55 | 2024-03-01 | Buy |
| TCI Chemical | I0102 | Isobutyramide >98.0%(GC) | 563-83-7 | 500g | $635 | 2024-03-01 | Buy |
| Alfa Aesar | B21641 | Isobutyramide, 99% | 563-83-7 | 25g | $58.65 | 2024-03-01 | Buy |
Isobutyramide Chemical Properties,Uses,Production
Chemical Properties
white needle-like crystalline powder
Uses
Isobutyramide could be a useful compound for technical applications as a component in environmentally-friendly automobile welding anti-spatter liquid.
Uses
Isobutyramide plays an important role in chemical grafting of human serum albumin during the synthesis of sequentially assembled protein capsules. It is used in pharmaceutical manufacturing and in cellular differentiation. It finds application in the transcription of human gamma-globin gene and murine embryonic epsilon(y)-globin gene. Further, it is in the treatment of beta-thalassemia and sickle cell disease.
Application
Isobutyramide was used for chemical grafting of human serum albumin during the synthesis of sequentialy assembled protein capsules.
Isobutyramide plays an important role in chemical grafting of human serum albumin during the synthesis of sequentially assembled protein capsules. It is used in pharmaceutical manufacturing and in cellular differentiation. It finds application in the transcription of human gamma-globin gene and murine embryonic epsilon(y)-globin gene. Further, it is in the treatment of beta-thalassemia and sickle cell disease.
Definition
ChEBI: Isobutyramide is a carboximidic acid.
Synthesis Reference(s)
Journal of the American Chemical Society, 69, p. 2058, 1947 DOI: 10.1021/ja01200a070
Biochem/physiol Actions
Isobutyramide activates transcription of human gamma-globin gene and murine embryonic epsilon(y)-globin gene. It is useful in the treatment of β-thalassemia and sickle cell disease.
Purification Methods
Crystallise the amide from acetone, *benzene, CHCl3, EtOAc or water, then dry it under vacuum over P2O5 or 99% at H2SO4, or at 70o/3hours in a desiccator. Sublime it under vacuum. [Kent & McAlvain Org Synth Coll Vol III 491 1955, Beilstein 2 H 293, 2 I 129, 2 II 262, 2 III 654, 2 IV 852.]
Isobutyramide Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8812 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12840 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3002 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29884 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2136 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
View Lastest Price from Isobutyramide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2024-11-20 | Isobutyramide
563-83-7
|
US $180.00 / kg | 1kg | 99% | 20ton | Hebei Zhuanglai Chemical Trading Co.,Ltd | |
 |
2024-11-13 | Isobutyramide
563-83-7
|
US $10.00 / KG | 1KG | 99% | 10 mt | Hebei Weibang Biotechnology Co., Ltd | |
 |
2023-08-24 | Isobutyramide
563-83-7
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd |
-
- Isobutyramide
563-83-7
- US $180.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd
-
- Isobutyramide
563-83-7
- US $10.00 / KG
- 99%
- Hebei Weibang Biotechnology Co., Ltd
-
- Isobutyramide
563-83-7
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd