Anticholinesterase
- CAS No.
- 9000-81-1
- Chemical Name:
- Anticholinesterase
- Synonyms
- ACHE;ACETYLCHOLINESTERASE;Native Electrophorus electricus (electric eel) Acetylcholinesterase;AcCholE;EC 3.1.1.7;Cholinesterase I;ANTICHOLINESTERASE;TRUE CHOLINESTERASE;Acetylcholinesterases;ACETYLCHOLINE ESTERASE
- CBNumber:
- CB8359935
- Molecular Formula:
- NULL
- Molecular Weight:
- 0
- MDL Number:
- MFCD00081268
- MOL File:
- Mol file
storage temp. | -20°C |
---|---|
solubility | H2O: 1 mg/mL |
form | powder |
color | slightly yellow |
FDA UNII |
ACETYLCHOLINESTERASE ELECTROPHORUS ELECTRICUS (83KH8K2107) ACETYLCHOLINESTERASE HUMAN (EK71H4HC3N) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS08 |
---|---|
Signal word | Danger |
Hazard statements | H334 |
Precautionary statements | P261-P285-P304+P341-P342+P311-P501 |
Hazard Codes | B |
WGK Germany | 3 |
F | 10-21 |
Toxicity | The inhibition of AChE by these anticholinesterases leads to an accumulation of endogenous ACh, and thus results in hyperactivation of cholinergic receptors. Signs of acute poisoning can include irritability, tremors, convulsions, and predominately parasympathetic effects, with death usually the result of respiratory failure. Since AChE is contained in erythrocytes, the assay of erythrocyte AChE activity can be used as a diagnostic tool to assess exposure to organophosphorus anticholinesterases. |
Anticholinesterase price More Price(23)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | C3389 | Acetylcholinesterase from Electrophorus electricus (electric eel) Type VI-S, lyophilized powder, 200-1,000?units/mg protein | 9000-81-1 | 500units | $95 | 2024-03-01 | Buy |
Sigma-Aldrich | C3389 | Acetylcholinesterase from Electrophorus electricus (electric eel) Type VI-S, lyophilized powder, 200-1,000?units/mg protein | 9000-81-1 | 2000units | $252 | 2024-03-01 | Buy |
Sigma-Aldrich | C3389 | Acetylcholinesterase from Electrophorus electricus (electric eel) Type VI-S, lyophilized powder, 200-1,000?units/mg protein | 9000-81-1 | 10000units | $862 | 2024-03-01 | Buy |
Sigma-Aldrich | C2888 | Acetylcholinesterase from Electrophorus electricus (electric eel) Type V-S, lyophilized powder, ≥1,000?units/mg protein | 9000-81-1 | 500units | $133 | 2024-03-01 | Buy |
Sigma-Aldrich | C2888 | Acetylcholinesterase from Electrophorus electricus (electric eel) Type V-S, lyophilized powder, ≥1,000?units/mg protein | 9000-81-1 | 1000units | $268 | 2024-03-01 | Buy |
Anticholinesterase Chemical Properties,Uses,Production
Uses
Pesticides.
Uses
Acetylcholinesterase from Electrophorus electricus (electric eel) has been used:
- in acetylcholinesterase activity assay
- to study its effects on Xenopus embryonic hippocampal cells
- to study the effect of acetylcholine inhibitors on development and plasticity
Uses
Acetylcholinesterase (AChE) from Sigma has been used in the structure-activity study of phosphoramido acid esters as inhibitors of AChE.
Definition
Any substance that inhibits or inactivates acetylcholinesterase, thereby preventing the hydrolysis of acetylcholine. Their action leads to an accumulation of endogenous acetylcholine with a resultant hyperactivity of cholinergic neurons, which can prove lethal.
General Description
Predominantly exists as a tetrameric glycoprotein composed of disulfide-linked homodimers with a monomer MW of ~80 kDa.
Hazard
Tremors; convulsions; respiratory failure; death.
Biochem/physiol Actions
Acetylcholinesterase (AChE) is regarded as a biomarker in neurotoxicity. It is a modulator of nitric oxide signal transduction pathway and marker of membrane integrity and aging. The levels of erythrocyte (RBC) AChE are affected on pesticide exposure and in hemolytic anemia. RBC AChE is a marker in Hirschsprung′s disease and inflammation.
Anticholinesterase Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21663 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10326 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34571 | 58 |
HONG KONG IPURE BIOLOGY CO.,LIMITED | 86 18062405514 18062405514 | ada@ipurechemical.com | CHINA | 3465 | 58 |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23555 | 58 |
Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 | info@fortunachem.com | China | 5987 | 58 |
Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 | dominicguo@gk-bio.com | CHINA | 9427 | 58 |
View Lastest Price from Anticholinesterase manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-09-18 | Anticholinesterase
9000-81-1
|
US $0.00-0.00 / g | 1g | 98.0% | 1kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
2019-07-06 | Anticholinesterase
9000-81-1
|
US $1.00 / kg | 1kg | 95%-99% | 100kg | Career Henan Chemical Co |
- Anticholinesterase
9000-81-1
- US $0.00-0.00 / g
- 98.0%
- WUHAN FORTUNA CHEMICAL CO., LTD
- Anticholinesterase
9000-81-1
- US $1.00 / kg
- 95%-99%
- Career Henan Chemical Co
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