PAF (C18)
- CAS No.
- 74389-69-8
- Chemical Name:
- PAF (C18)
- Synonyms
- C18 PAF;PAF (C18);ro14-8161;C18-02:0 PC;PAF (C18),99%;c18-paf-acether;PLATELET ACTIVATING FACTOR-18;PLATELET ACTIVATING FACTOR (C18);hydroxide,innersalt,4-oxide,(r)-thyl;1-O-STEARYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE
- CBNumber:
- CB8371788
- Molecular Formula:
- C28H58NO7P
- Molecular Weight:
- 551.74
- MDL Number:
- MFCD00063528
- MOL File:
- 74389-69-8.mol
| storage temp. | -20°C |
|---|---|
| solubility | chloroform: 10 mg/mL |
| FDA UNII | C9ZA6E5Q2B |
SAFETY
Risk and Safety Statements
| Safety Statements | 24/25 |
|---|---|
| WGK Germany | 3 |
| HS Code | 29310099 |
PAF (C18) price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 60910 | PAF C-18 ≥97% | 74389-69-8 | 5mg | $70 | 2024-03-01 | Buy |
| Cayman Chemical | 60910 | PAF C-18 ≥97% | 74389-69-8 | 10mg | $120 | 2024-03-01 | Buy |
| Cayman Chemical | 60910 | PAF C-18 ≥97% | 74389-69-8 | 1mg | $36 | 2024-03-01 | Buy |
| Cayman Chemical | 60910 | PAF C-18 ≥97% | 74389-69-8 | 25mg | $257 | 2024-03-01 | Buy |
| AK Scientific | 1976AH | 1-O-Octadecyl-2-Acetyl-Sn-Glycero-3-Phosphocholine | 74389-69-8 | 25mg | $383 | 2021-12-16 | Buy |
PAF (C18) Chemical Properties,Uses,Production
Chemical Properties
white solid
Uses
C18-02:0 PC or 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine may be used as a substrate in enzymatic lipoprotein-associated phospholipase A2 (Lp-PLA2) activity assay.
Uses
C18-02:0 PC or 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine is suitable as a substrate for enzymatic lipoprotein-associated phospholipase A2 (Lp-PLA2) activity assay.
Definition
ChEBI: 2-acyl-1-alkyl-sn-glycero-3-phosphocholine betaine in which the 1-alkyl and 2-acyl groups are specified as octacdecyl and acetyl respectively
General Description
C18-02:0 PC, also known as 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine (C18∶0-PAF), is a platelet-activating factor lipid. It belongs to a class of natural PAFs and is produced in basophil leucocytes, macrophages, polymorphonuclear neutrophils and monocytes and platelets.
Biochem/physiol Actions
C18-02:0 PC or 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine (C18-PAF), a platelet-activating factor (PAF) facilitates platelet aggregation and secretion. It also plays a key role in inflammation and anaphylaxis. C18-PAF exhibits neurotoxic effects by initiating caspase-independent death in PAF receptor-deficient neurons.
PAF (C18) Preparation Products And Raw materials
Raw materials
Preparation Products
PAF (C18) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32165 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30240 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57505 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94657 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 021-61259108 18621169109 | market03@meryer.com | China | 40228 | 62 |
| Thermo Fisher Scientific | 800-810-5118 | cnchemical@thermofisher.com | China | 17770 | 75 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-400-6206333 18521732826 | market@aladdin-e.com | China | 25003 | 65 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51456 | 80 |
| Codow Chemical Co.,Ltd. | 18620099427 | amy@howeipharm.com | China | 17687 | 55 |
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