Gomisin A
- CAS No.
- 58546-54-6
- Chemical Name:
- Gomisin A
- Synonyms
- D01752;TJN-101;GOMISIN A;Besigomsin;BESIGOMISIN;wuweizichunb;SCHIZANDROL B;SCHISANDROL B;wuweizialcoholb;Grifola frondsa
- CBNumber:
- CB8374224
- Molecular Formula:
- C23H28O7
- Molecular Weight:
- 416.47
- MDL Number:
- MFCD01941645
- MOL File:
- 58546-54-6.mol
- MSDS File:
- SDS
Melting point | 88.5°C |
---|---|
Boiling point | 454.79°C (rough estimate) |
Density | 1.1772 (rough estimate) |
refractive index | 1.5300 (estimate) |
storage temp. | Sealed in dry,Store in freezer, under -20°C |
solubility | DMSO : 50 mg/mL (120.06 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble) |
form | powder to crystal |
pka | 14.58±0.40(Predicted) |
color | White to Light yellow |
LogP | 4.770 (est) |
FDA UNII | L5U70J87J8 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H302 | |||||||||
Precautionary statements | P501-P270-P264-P301+P312+P330 | |||||||||
Safety Statements | 24/25 | |||||||||
HS Code | 29329990 | |||||||||
NFPA 704 |
|
Gomisin A price More Price(45)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TCI Chemical | G0537 | Gomisin A | 58546-54-6 | 5MG | $72 | 2024-03-01 | Buy |
TCI Chemical | G0537 | Gomisin A | 58546-54-6 | 25MG | $258 | 2024-03-01 | Buy |
Cayman Chemical | 25149 | Schisandrol B ≥98% | 58546-54-6 | 1mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 25149 | Schisandrol B ≥98% | 58546-54-6 | 5mg | $93 | 2024-03-01 | Buy |
Cayman Chemical | 25149 | Schisandrol B ≥98% | 58546-54-6 | 10mg | $169 | 2024-03-01 | Buy |
Gomisin A Chemical Properties,Uses,Production
Description
Schisandrol B is a lignan originally isolated from S. chinensis that has hepatoprotective activity. It increases the expression of pregnane X receptor (PXR) target genes involved in bile acid metabolism, including Cyp3a11, Ugt1a1, Oatp2, and Mrp3 in mouse liver and CYP3A4, UGT1A1, and OATP2 in HEK293T cells. It also protects against lithocholic acid-induced hepatic necrosis and intrahepatic cholestasis in wild-type, but not Pxr-null, mice and decreases mortality in a mouse model of cholestasis when administered at a dose of 100 mg/kg twice per day. It also promotes liver regeneration following partial hepatectomy and protects against hepatotoxicity induced by acetaminophen .
Chemical Properties
White powder
Uses
Schizandrol B exhibits potent protective effects of on ET-1-induced dysfunctional human-induced pluripotent stem cell-derived cardiomyocytes (hiPS-CMs). Anti-cholestasis effect.
Gomisin A Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 16914 | 58 |
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29894 | 58 |
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3777 | 58 |
Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
View Lastest Price from Gomisin A manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2024-08-23 | Gomisin A
58546-54-6
|
US $0.00-0.00 / mg | 20mg | 98% HPLC | 100kg | Changsha Staherb Natural Ingredients Co., Ltd. | |
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2023-02-24 | Gomisin A
58546-54-6
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
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2019-07-14 | Gomisin A
58546-54-6
|
US $1.00 / KG | 1KG | 99% | 25kg | Career Henan Chemical Co |
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