4-(Chloromethyl)pyridine hydrochloride
- CAS No.
- 1822-51-1
- Chemical Name:
- 4-(Chloromethyl)pyridine hydrochloride
- Synonyms
- 4-PICOLYL CHLORIDE HYDROCHLORIDE;4-Picolyl chloride;TIMTEC-BB SBB003917;4-Picolyl chloride h;4-(Chloromethyl)pyridine HCL;4-Plcolyl Chloride Hydrochloride;4-(Chloromethyl) Pyridine HCL 99%;4-(Chloromethyl)pyridine hydrochl;4-(CHLOROMETHYL)PYRIDINIUM CHLORIDE;4-Picolyl chloride hydrochloride,97%
- CBNumber:
- CB8380214
- Molecular Formula:
- C6H6ClN.ClH
- Molecular Weight:
- 164.03
- MDL Number:
- MFCD00012826
- MOL File:
- 1822-51-1.mol
- MSDS File:
- SDS
Melting point | 166-173 °C(lit.) |
---|---|
storage temp. | Inert atmosphere,2-8°C |
solubility | soluble in DMSO, Methanol |
form | Fine Crystalline Powder |
color | Yellow to orange |
Water Solubility | 750 g/L (20 ºC) |
Sensitive | Hygroscopic |
BRN | 3689154 |
CAS DataBase Reference | 1822-51-1(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS05 |
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Signal word | Danger | |||||||||
Hazard statements | H314 | |||||||||
Precautionary statements | P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363 | |||||||||
Hazard Codes | C,Xi | |||||||||
Risk Statements | 34-4-22-36/37/38 | |||||||||
Safety Statements | 26-36/37/39-45-36 | |||||||||
RIDADR | UN 3261 8/PG 3 | |||||||||
WGK Germany | 3 | |||||||||
F | 3-10 | |||||||||
Hazard Note | Corrosive | |||||||||
HazardClass | 8 | |||||||||
PackingGroup | III | |||||||||
HS Code | 29333999 | |||||||||
NFPA 704 |
|
4-(Chloromethyl)pyridine hydrochloride price More Price(30)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | P43807 | 4-(Chloromethyl)pyridine hydrochloride 97% | 1822-51-1 | 10g | $24.8 | 2024-03-01 | Buy |
Sigma-Aldrich | P43807 | 4-(Chloromethyl)pyridine hydrochloride 97% | 1822-51-1 | 100g | $160 | 2024-03-01 | Buy |
TCI Chemical | C0805 | 4-(Chloromethyl)pyridine Hydrochloride >98.0%(HPLC)(T) | 1822-51-1 | 25g | $113 | 2024-03-01 | Buy |
TCI Chemical | C0805 | 4-(Chloromethyl)pyridine Hydrochloride >98.0%(HPLC)(T) | 1822-51-1 | 250g | $675 | 2024-03-01 | Buy |
Alfa Aesar | A12859 | 4-(Chloromethyl)pyridine hydrochloride, 98% | 1822-51-1 | 5g | $31.65 | 2024-03-01 | Buy |
4-(Chloromethyl)pyridine hydrochloride Chemical Properties,Uses,Production
Chemical Properties
YELLOW TO ORANGE FINE CRYSTALLINE POWDER
Uses
It finds its application as a reagent for protection of carboxyl termini of peptides as 4-picolyl esters, providing a polar 'handle' which aids in separation and purification of the peptide. The group can be introduced in the presence of a base, e.g. tetramethylguanidine, is stable to acid-catalyzed removal of Cbz protecting group and can be removed by base, Na in liquid ammonia or catalytic hydrogenolysis. It is also applied in conjunction with Amberlyst?15 resin in peptide synthesis. It is an important raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals.
Purification Methods
Purify it by recrystallisation from EtOH or EtOH/dry Et2O. It melts between 171o and 175o, and the clear melt resolidifies on further heating at 190o and turns red to black at 280o but does not melt again. The picrate-hydrochloride (prepared in EtOH) has m 146-147o. The free base is an oil. [Mosher & Tessieri J Am Chem Soc 73 4925 1951, Beilstein 20 III/IV 2752.]
4-(Chloromethyl)pyridine hydrochloride Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12834 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5857 | 58 |
Hebei Weibang Biotechnology Co., Ltd | +8617732866630 | bess@weibangbio.com | China | 18150 | 58 |
Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29880 | 58 |
Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
View Lastest Price from 4-(Chloromethyl)pyridine hydrochloride manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-11-05 | 4-(Chloromethyl)pyridine hydrochloride
1822-51-1
|
US $30.00-10.00 / KG | 50KG | 99% | 500000kg | Hebei Weibang Biotechnology Co., Ltd | ||
2024-10-25 | 4-(Chloromethyl)pyridine hydrochloride
1822-51-1
|
US $15.00-6.00 / kg | 1kg | 0.99 | 10 tons | Hebei Yanxi Chemical Co., Ltd. | ||
2023-10-11 | 4-(Chloromethyl)pyridine hydrochloride
1822-51-1
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd |
- 4-(Chloromethyl)pyridine hydrochloride
1822-51-1
- US $30.00-10.00 / KG
- 99%
- Hebei Weibang Biotechnology Co., Ltd
- 4-(Chloromethyl)pyridine hydrochloride
1822-51-1
- US $15.00-6.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
- 4-(Chloromethyl)pyridine hydrochloride
1822-51-1
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd