CASPASE-1 INHIBITOR TFA SALT
- CAS No.
- 210345-00-9
- Chemical Name:
- CASPASE-1 INHIBITOR TFA SALT
- Synonyms
- Z-WEHD-FMK-TFA;CASPASE-1 INHIBITOR TFA SALT;Caspase-1/ICE Inhibitor Z-WEHD-FMK;Z-TRP-GLU(OME)-HIS-ASP(OME)-FMK-TFA;Z-WE(OME)HD(OME)-FMK;Z-TRP-GLU(OME)-HIS-ASP(OME)-FMK;Z-TRP-GLU(OME)-HIS-ASP(OME)-FLUOROMETHYLKETONE;N-[(Phenylmethoxy)carbonyl]-L-tryptophyl-L-alpha-glutamyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-L-histidinamide methyl ester;L-Histidinamide, N-[(phenylmethoxy)carbonyl]-L-tryptophyl-L-α-glutamyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-, methyl ester (9CI)
- CBNumber:
- CB8382359
- Molecular Formula:
- C37H42FN7O10
- Molecular Weight:
- 763.77
- MDL Number:
- MFCD07780829
- MOL File:
- 210345-00-9.mol
CASPASE-1 INHIBITOR TFA SALT price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ApexBio Technology | A1924 | Z-WEHD-FMK | 210345-00-9 | 5mg | $450 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0002128 | CASPASE-1 INHIBITOR TFA SALT 95.00% | 210345-00-9 | 5MG | $505.63 | 2021-12-16 | Buy |
| ChemScene | CS-0018267 | Z-WEHD-FMK 98.64% | 210345-00-9 | 10mg | $650 | 2021-12-16 | Buy |
CASPASE-1 INHIBITOR TFA SALT Chemical Properties,Uses,Production
Biological Activity
treatment of infected cells with pan-caspase inhibitor iv and z-wehd-fmk, an inhibitor of inflammatory caspases, elicited a near-complete blockage of c. trachomatis-induced cleavage of golgin-84. golgin-84 cleavage was blocked via treatment of infected cells with z-wehd-fmk, resulting in a lack of golgi fragmentation and a 2-log reduction in numbers of infectious bacteria.we treated infected cells with z-wehd-fmk, effectively preventing golgi fragmentation, or with dmso as a control and then labelled cells with fluorescent ceramide. confocal images revealed that ceramide was rapidly incorporated into the inclusion membrane within dmso-treated cells and accumulated inside the inclusion in bacterial membranes. in contrast, z-wehd-fmk-treated cells were only slightly fluorescent as the majority of lipid accumulated in a golgi-like structure outside the inclusion1.general caspase inhibitor (z-asp-chz-dcb) and capase-5 inhibitor (z-wehd-fmk) could not induce rrna fragmentation treated with ecyd. caspase-5 (icerei ill/ty), member of ice protease, activated pathway may be concerned with ecyd induced rrna fragmentation2.
target
caspase-5
References
1. d. heuer, a.r. lipinski et al. chlamydia causes fragmentation of the golgi compartment to ensure reproduction. nature, 457, 2009 2. kamada, s., funahashi, y. and tsujimoto, y.(1997) cell death diff. 4, 473-478.
CASPASE-1 INHIBITOR TFA SALT Preparation Products And Raw materials
Raw materials
Preparation Products
CASPASE-1 INHIBITOR TFA SALT Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19741 | 58 |
| ApexBio Technology LLC | +1-832-696-8203 | info@apexbt.com | United States | 477 | 60 |
| Creative Peptides | info@creative-peptides.com | United States | 6083 | 56 | |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 | psaitong@jm-bio.com | China | 12306 | 58 |
| Jinan ponder chemical co. LTD | 0531-0000 | thinklifescience@163.com | China | 19689 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11217 | 58 |
| Absin Bioscience Inc. | 021-38015121 15000105423 | wulan@absin.cn | China | 24731 | 58 |
| Nanchang Tianzhen Biotechnology Co., Ltd | 13173652190 | pomy@tanzhenbio.com | China | 1775 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8140 | 58 |
| cjbscvictory | 13348960310 13348960310 | 3003867561@qq.com | China | 10002 | 58 |