N1,N3-Bis(1,3-dihydroxypropan-2-yl)-5-(2-hydroxypropanamido)-2,4,6-triiodoisophthalamide
- CAS No.
- 62883-00-5
- Chemical Name:
- N1,N3-Bis(1,3-dihydroxypropan-2-yl)-5-(2-hydroxypropanamido)-2,4,6-triiodoisophthalamide
- Synonyms
- Iodopanol;Iopamidol CRS;Iodine, alcohol;2-[2-[(7-chloro-4-quinazolinyl)amino]ethoxy]ethanol;N,N'-bis(2-hydroxy-1-methylol-ethyl)-2,4,6-triiodo-5-lactamido-isophthalamide;N1,N3-Bis(1,3-dihydroxypropan-2-yl)-5-(2-hydroxypropanamido)-2,4,6-triiodoisophthalamide;N,N'-BIS(1,3-DIHYDROXYPROPAN-2-YL)-5-(2-HYDROXYPROPANOYLAMINO)-2,4,6-TRIIODO-BENZENE-1,3-DICARBOXAMIDE;N1,N3-bis(1,3-dihydroxypropan-2-yl)-5-(2-hydroxypropanoylamino)-2,4,6-triiodo-benzene-1,3-dicarboxamide;1-N,3-N-bis(1,3-dihydroxypropan-2-yl)-5-(2-hydroxypropanoylamino)-2,4,6-triiodobenzene-1,3-dicarboxamide;(S)-N,N'-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)amino]-2,4,6-triiodoisophthaldiamide
- CBNumber:
- CB8384797
- Molecular Formula:
- C17H22I3N3O8
- Molecular Weight:
- 777.09
- MDL Number:
- MFCD00867931
- MOL File:
- 62883-00-5.mol
- MSDS File:
- SDS
Melting point | >283oC (dec.) |
---|---|
storage temp. | -20°C Freezer, Under inert atmosphere |
solubility | Water (Slightly) |
form | Solid |
pka | pKa 10.70(H2O,t = 25.0) (Uncertain) |
color | White |
CAS DataBase Reference | 62883-00-5(CAS DataBase Reference) |
FDA UNII | JR13W81H44 |
NCI Drug Dictionary | iopamidol |
ATC code | V08AB04 |
N1,N3-Bis(1,3-dihydroxypropan-2-yl)-5-(2-hydroxypropanamido)-2,4,6-triiodoisophthalamide Chemical Properties,Uses,Production
Description
Lopamidol is a benzenedicarboxamide compound having N-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and a (2S)-2-hydroxypropanamido group at the 5-position. It has a role as a radioopaque medium, an environmental contaminant and a xenobiotic. Lopamidol is a Radiographic Contrast Agent, it is a benzenedicarboxamide, an organoiodine compound and a pentol.
Uses
Lopamidol is a radiopaque (RAY dee oh payk) contrast agent to help diagnose or find problems in the brain, heart, head, blood vessels, and other parts of the body. Iopamidol contains iodine, a substance that absorbs x-rays. Radiopaque contrast agents are used to allow blood vessels, organs, and other non-bony tissues to be seen more clearly on a CT scan or other radiologic (x-ray) examination.
Uses
Diagnostic aid (radiopaque medium.
Definition
ChEBI: Iopamidol is a benzenedicarboxamide compound having N-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and a (2S)-2-hydroxypropanamido group at the 5-position. It has a role as a radioopaque medium, an environmental contaminant and a xenobiotic. It is a benzenedicarboxamide, an organoiodine compound and a pentol.
Indications
Iopamidol is indicated for angiography throughout the cardiovascular system in adults, including cerebral and peripheral arteriography, coronary arteriography and ventriculography, selective visceral arteriography and aortography, peripheral venography (phlebography), and in pediatric patients for angiocardiography; or for intravenous use in adult and pediatric for computed tomographic (CT) imaging of the head and body.
brand name
Isovue (Bracco).
Side effects
Serious Effects: Decreased urination, severe headache, dizziness, convulsion, irregular heart beat, feeling light-headed, fainting, breathing trouble, fever, chills, nausea and vomiting.
Local: Pain, tenderness, redness or skin changes.
Less Common: Joint or muscle pain, back ache, stiff neck, numbness, warmth, or tingly feeling, ringing in the ears, increased sweating, itchy skin, chills, stuffy nose, sneezing, confusion, slurred speech.
N1,N3-Bis(1,3-dihydroxypropan-2-yl)-5-(2-hydroxypropanamido)-2,4,6-triiodoisophthalamide Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
HAINAN POLY PHARMCEUTICAL CO. LTD | +86-0571-89385087 +8613616530509 | ff@hnpoly.com | China | 118 | 58 |
Jiangsu Yutian pharmaceutical Co.,Ltd. | +undefined-0518-86098006 +undefined19851887368 | lvan.hui@jsytsw.com | China | 80 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29894 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34571 | 58 |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23556 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 8853 | 58 |
AFINE CHEMICALS LIMITED | +86-0571-85134551 | info@afinechem.com | China | 15395 | 58 |
Yangzhou Model Electronic Materials Co., Ltd. | +8613761402923 | sales@modeltemol.com | CHINA | 571 | 58 |
CD Chemical Group Limited | +8615986615575 | info@codchem.com | China | 20356 | 58 |