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ChemicalBook >> CAS DataBase List >>(2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol

(2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol

(2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol Structure
(2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol structure
CAS No.
1382486-90-9
Chemical Name:
(2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol
Synonyms
(R)-FTY720-OME;Benzenebutanol, β-amino-β-(methoxymethyl)-4-octyl-, (βR)-;(2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol
CBNumber:
CB83945610
Molecular Formula:
C20H35NO2
Molecular Weight:
321.4974
MDL Number:
MFCD28143604
MOL File:
1382486-90-9.mol
Last updated:2024-10-28 23:16:16
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(2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol Properties

Boiling point 464.5±45.0 °C(Predicted)
Density 0.980±0.06 g/cm3(Predicted)
storage temp. -20°C
pka 12.51±0.20(Predicted)

(2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol Chemical Properties,Uses,Production

Definition

ChEBI: (2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol is a 2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol that has R-configuration. It is a sphingosine kinase-2 inhibitor. It has a role as an EC 2.7.1.91 (sphingosine kinase) inhibitor.

General Description

(R)-FTY720-OMe is a structural analogue of FTY720 which acts as a specific competitive inhibitor of sphingosine kinase 2 (SK2). Furthermore, (R)-FTY720-OMe does not inhibit sphingosine kinase 1 (SK1) activity.

Biochem/physiol Actions

(R)-FTY720-OMe helps to block DNA synthesis and actin rearrangement induced by sphingosine 1-phosphate (S1P) in MCF-7 breast cancer cells. It can also reduce sphingosine kinase 2 (SK2) expression and prevent DNA synthesis in HEK 293 cells. (R)-FTY720-OMe has anti-breast cancer potential.

(2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol Preparation Products And Raw materials

Raw materials

Preparation Products

(2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
Creative Enzymes 		1-516-855-7709 info@creative-enzymes.com United States 8748 58
TargetMol Chemicals Inc. 		+8613564774135 zijue.cai@tsbiochem.com United States 19885 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51456 80
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19704 58
SHANGHAI ZZBIO CO., LTD. 15102117276 19921389125 tech@zzbioco.com China 12065 58
Supplier Advantage
Creative Enzymes 		58
TargetMol Chemicals Inc. 		58
Sigma-Aldrich 80
TargetMol Chemicals Inc. 58
SHANGHAI ZZBIO CO., LTD. 58

View Lastest Price from (2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(R)-FTY720-OMe pictures 2024-10-28 (R)-FTY720-OMe
1382486-90-9
 US $1520.00-1980.00 / mg 10g TargetMol Chemicals Inc.
  • (R)-FTY720-OMe pictures
  • (R)-FTY720-OMe
    1382486-90-9
  • US $1520.00-1980.00 / mg
  • TargetMol Chemicals Inc.
(2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol (R)-FTY720-OME Benzenebutanol, β-amino-β-(methoxymethyl)-4-octyl-, (βR)- 1382486-90-9