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N-NITROSODIETHANOLAMINE

CAS No.
1116-54-7
Chemical Name:
N-NITROSODIETHANOLAMINE
Synonyms
ndela;nci-c55583;rcrawastenumberu173;diaethanolnitrosamin;DIETHANOLNITROSAMINE;diethanolnitrosoamine;nitrosodiethanolamine;nitrosoiminodiethanol;N-DIETHANOLNITROSAMINE;N-Nitrosoamindiethanol
CBNumber:
CB8401443
Molecular Formula:
C4H10N2O3
Molecular Weight:
134.13
MDL Number:
MFCD00015522
MOL File:
1116-54-7.mol
Last updated:2024-07-14 20:44:35

N-NITROSODIETHANOLAMINE Properties

Melting point 200 °C (decomp)
Boiling point bp0.01 125°
Density 1,26 g/cm3
refractive index nD20 1.4849
Flash point 11℃
storage temp. 2-8°C
Water Solubility Completely miscible in water
solubility DMSO (Soluble), Ethyl Acetate (Sparingly), Methanol (Soluble), Water (Sparingly)
form clear liquid to slightly cloudy liquid
pka 13.76±0.10(Predicted)
color Light yellow to Brown
Merck 14,6634
BRN 1762620
CAS DataBase Reference 1116-54-7(CAS DataBase Reference)
FDA UNII 30YI1289VY
IARC 2B (Vol. 17, Sup 7, 77) 2000
Proposition 65 List n-Nitrosodiethanolamine
EPA Substance Registry System N-Nitrosodiethanolamine (1116-54-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07,GHS08
Signal word  Danger
Hazard statements  H225-H319-H350
Precautionary statements  P201-P210-P305+P351+P338-P308+P313
Hazard Codes  T,F
Risk Statements  45-11
Safety Statements  53-45-16
RIDADR  UN 1993 3/PG 2
WGK Germany  1
RTECS  KL9550000
HS Code  2922.19.9690
HazardClass  3.1
PackingGroup  II
Toxicity LD50 orl-rat: 7500 mg/kg GISAAA 40(1),81,75
NFPA 704
3
2 0

N-NITROSODIETHANOLAMINE price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich N7632 N-Nitrosodiethanolamine 1116-54-7 1g $84.4 2024-03-01 Buy
Sigma-Aldrich N7632 N-Nitrosodiethanolamine 1116-54-7 500mg $113 2024-03-01 Buy
TCI Chemical N0438 N-Nitrosodiethanolamine >97.0%(GC) 1116-54-7 5g $288 2024-03-01 Buy
TCI Chemical N0438 N-Nitrosodiethanolamine >97.0%(GC) 1116-54-7 25g $716 2024-03-01 Buy
TRC N525200 Nitrosobis(2-hydroxyethyl)amine 1116-54-7 100mg $45 2021-12-16 Buy
Product number Packaging Price Buy
N7632 1g $84.4 Buy
N7632 500mg $113 Buy
N0438 5g $288 Buy
N0438 25g $716 Buy
N525200 100mg $45 Buy

N-NITROSODIETHANOLAMINE Chemical Properties,Uses,Production

Chemical Properties

Reddish Yellow Oil

Uses

A potent liver carcinogen in several species of animals, is one of the most widespread N-nitroso compounds in the human environment.

Definition

ChEBI: N-Nitrosodiethanolamine is a nitroso compound.

General Description

Yellow to dark brown very viscous liquid with no distinct odor.

Air & Water Reactions

Water soluble.

Reactivity Profile

N-NITROSODIETHANOLAMINE can react with alkoxides. N-NITROSODIETHANOLAMINE reacts with sulfuric acid at temperatures above 311° F.

Health Hazard

ACUTE/CHRONIC HAZARDS: N-NITROSODIETHANOLAMINE may be harmful by eye or skin contact, inhalation or ingestion. It is an irritant and, when heated to decomposition, it emits toxic fumes of carbon monoxide, carbon dioxide and nitrogen oxides.

Fire Hazard

Flash point data for N-NITROSODIETHANOLAMINE are not available; however, N-NITROSODIETHANOLAMINE is probably combustible.

Safety Profile

Confirmed carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data.Mildly toxic by ingestion. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also N-NITROSO COMPOUNDS and ALCOHOLS.

Carcinogenicity

N-Nitrosodiethanolamine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

Purification Methods

Purify NDELA by dissolving the amine (0.5g) in 1-propanol (10mL) and 5g of anhydrous Na2SO4 added with stirring. After standing for 1-2hours, it is filtered and passed through a chromatographic column packed with 10mL of AG 50W x 8 (H+form 50-100mesh, a strongly acidic cation exchanger). The eluent and washings (50 mL EtOH) are combined and evaporated to dryness at 35o. It has also been extracted with EtOH from the nitrosation mixture of ethanolamine, filtered and distilled under high vacuum. [Fukuda et al. Anal Chem 53 2000 1981, Jones & Wilson J Chem Soc 550, 1949, Beilstein 1 III 721, see Spiegelhalder et al. N-Nitroso Compounds: Occurrence Biological Effects and Relevance in Human Cancer (eds. O’Neill et al. IARC Scientific Publications No 57; IARC Lyon p943 1984.] Possible

111-42-2
1116-54-7
Synthesis of N-NITROSODIETHANOLAMINE from Diethanolamine
Global( 108)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Dideu Medichem Co. Ltd
+86-29-81148696 +86-15536356810 1022@dideu.com China 3882 58
Chemsigma International Co., Ltd.
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Aladdin Scientific
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SHANGHAI KEAN TECHNOLOGY CO., LTD.
+8613817748580 cooperation@kean-chem.com China 40066 58

View Lastest Price from N-NITROSODIETHANOLAMINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-NITROSODIETHANOLAMINE pictures 2024-07-14 N-NITROSODIETHANOLAMINE
1116-54-7
US $0.10 / KG 1KG 98.0% 10 Shaanxi Dideu Medichem Co. Ltd
2,2’-nitrosiminodi-ethano bis-(2-hydroxy-ethyl)-nitroso-amine bis(beta-hydroxyaethyl)nitrosamin bis(beta-hydroxyethyl)nitrosamine bis-2-hydroxy-ethyl-nitroso-amine di-(2-hydroxyethyl)-nitrosamine diaethanolnitrosamin diethanolnitrosoamine n,n-diethanolnitrosamine nci-c55583 ndela nitrosodiethanolamine nitrosoiminodiethanol n-nitrosoaminodiethanol n-nitrosobis(2-hydroxyethyl)amine n-Nitroso-bis(2-hydroxymethyl)-amine n-nitrosodiaethanolamin n-nitrosoiminodi-ethano 2,2'-dihydroxy-N-nitrosodiethylamine 2,2'-nitrosiminodiethanol N-Nitrosodiethanolamine? N-nitrosoiminodiethanol Ethanol, 2,2-(nitrosoimino)bis- N-DIETHANOLNITROSAMINE ETHANOL,N-NITROSOIMINODI- bis(beta-hydroxyaethyl)nitrosamin (german) diaethanolnitrosamin (german) rcrawastenumberu173 N-NITROSODIETHANOLAMINE DIETHANOLNITROSAMINE 2,2'-(Nitrosoimino)diethanol N,N-bis(2-hydroxyethyl)nitrous amide Nitrosobis(2-hydroxyethyl)amine Bis(2-hydroxyethyl)nitrosamine N-Nitrosodiethanolamine 2,2’-(nitrosoimino)bis-ethano 2,2’-dihydroxy-n-nitroso-diethylamin 2,2’-iminodi-n-nitrosoethanol 2,2’-(nitrosoimino)bisethanol 2,2’-(nitrosoimino)bis-Ethanol N-Nitrosodiethanolamine> N-Nitroso-diethanolamine Solution in Methanol, 1000μg/mL N-Nitrosoamindiethanol 2-[(2-hydroxyethyl)(nitroso)amino]ethan-1-ol 2,2′-(nitrosoimino)diethanol (N-nitrosodiethanolamine) Trolamine EP Impurity C N-nitroso-diethanolamine NDELA 3,7 1116-54-7 HOCD2CD2NNO Amines Nitric Oxide Reagents Nitrosamine pharmacetical