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4-Bromo-2-(trifluoromethoxy)aniline

4-Bromo-2-(trifluoromethoxy)aniline structure

CAS No.: 175278-09-8

Chemical Name:: 4-Bromo-2-(trifluoromethoxy)aniline

Synonyms: 4-BROMO-2-(TRIFLUOROMETHOXY)ANILINE;4-Bromo-2-trifluoromethoxy-phenylamine;BUTTPARK 50\01-74;TIMTEC-BB SBB005835;4-Bromo-2-Trifluoromethox;2-trifluoromethoxy-4-bromoaniline;4-bromo-2-(trifluoromrthoxy)aniline;4-Bromo-2-(trifluoeomethoxy)aniline;4-Bromo-2-trifluoromethoxyaniline,97%;4-Bromo-2-(trifluoromethoxy)aniline98%

CBNumber:: CB8419851

Molecular Formula:: C7H5BrF3NO

Molecular Weight:: 256.02

MDL Number:: MFCD00179338

MOL File:: 175278-09-8.mol

MSDS File:: SDS

Last updated:2025-01-27 09:38:02

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4-Bromo-2-(trifluoromethoxy)aniline Properties

Boiling point	98-100 °C/15 mmHg (lit.)
Density	1.691 g/mL at 25 °C (lit.)
refractive index	n20/D 1.5130(lit.)
Flash point	>230 °F
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
pka	1.75±0.10(Predicted)
CAS DataBase Reference	175278-09-8(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS06

Signal word

Danger

Hazard statements

H301-H317

Precautionary statements

P280-P301+P310+P330-P302+P352

Hazard Codes

T,Xi

Risk Statements

25-43-52/53-36/37/38

Safety Statements

36/37-45-37/39-26

RIDADR

UN 2810 6.1/PG 3

WGK Germany

Hazard Note

Toxic

HazardClass

IRRITANT

HazardClass

6.1

PackingGroup

Ⅲ

HS Code

29222990

NFPA 704

	1
2		0

4-Bromo-2-(trifluoromethoxy)aniline price More Price(30)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	631256	4-Bromo-2-(trifluoromethoxy)aniline 97%	175278-09-8	5g	$53.8	2022-05-15	Buy
Sigma-Aldrich	631256	4-Bromo-2-(trifluoromethoxy)aniline 97%	175278-09-8	25g	$233	2022-05-15	Buy
TCI Chemical	B3786	4-Bromo-2-(trifluoromethoxy)aniline >98.0%(GC)	175278-09-8	5g	$24	2024-03-01	Buy
TCI Chemical	B3786	4-Bromo-2-(trifluoromethoxy)aniline >98.0%(GC)	175278-09-8	25g	$63	2024-03-01	Buy
Alfa Aesar	B20885	4-Bromo-2-(trifluoromethoxy)aniline, 97%	175278-09-8	10g	$134	2021-12-16	Buy

Product number	Packaging	Price	Buy
631256	5g	$53.8	Buy
631256	25g	$233	Buy
B3786	5g	$24	Buy
B3786	25g	$63	Buy
B20885	10g	$134	Buy

4-Bromo-2-(trifluoromethoxy)aniline Chemical Properties,Uses,Production

Chemical Properties

clear pale yellow to orange-yellow liquid

Uses

4-Bromo-2-(trifluoromethoxy)aniline is a versatile building block that can be used to create a range of compounds, such as methyl 4- amino-3-(trifluoromethoxy)benzoate, 1-Bromo-3-(trifluoromethoxy)benzene, etc.
To a solution of 4-bromo-2-(trifluoromethoxy)aniline (10 g, 50.21 mmol) in methanol (150 mL) in a pressure tank reactor was added TEA (11.84 g, 117.01 mmol), Pd(dppf)Ci2 CH2Q2 (2.4 g, 2.94 mmol). Then the reactor was charged with CO (g) (20 atm). The resulting reaction was stirred for 1.5 days at 100°C. Then it was diluted with water (200 mL), extracted with ethyl acetate (3 x 100 mL) and the organic layers combined and dried in an oven under reduced pressure. The resulting mixture was concentrated in a vacuo. The residue was purified by silica gel column chromatography with ethyl acetate/petroleum ether (1:50) to afford methyl 4- amino-3-(trifluoromethoxy)benzoate as yellow solid (5 g, 54 %).

4-Bromo-2-(trifluoromethoxy)aniline Preparation Products And Raw materials

Raw materials

Preparation Products

3-(Trifluoromethoxy)bromobenzene

4-Bromo-2-(trifluoromethoxy)aniline Suppliers

Global( 230)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29730	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-+86-371-66670886	info@dakenam.com	China	19841	58
Hi-Tech Chemistry Corp	0519-86626038	yuhh@hitechem.com	CHINA	810	58
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	FandaChem@Gmail.com	China	3237	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	sales@dolonchem.com	CHINA	2972	58
Shanghai Worldyang Chemical Co.,Ltd.	+86-021-56795779 +8613651600618	sales@worldyachem.com	China	1227	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Hi-Tech Chemistry Corp	58
Hangzhou FandaChem Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
Changzhou Ansciep Chemical Co., Ltd.	58
Nanjing Dolon Biotechnology Co.,Ltd.	58
Shanghai Worldyang Chemical Co.,Ltd.	58
Hubei xin bonus chemical co. LTD	58
Alchem Pharmtech,Inc.	58

View Lastest Price from 4-Bromo-2-(trifluoromethoxy)aniline manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2022-07-30	4-Bromo-2-trifluoromethoxyaniline 175278-09-8	US $1.10 / g	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
2021-07-13	4-Bromo-2-trifluoromethoxyaniline 175278-09-8	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2021-07-10	4-Bromo-2-trifluoromethoxyaniline 175278-09-8	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd

4-Bromo-2-trifluoromethoxyaniline
175278-09-8
US $1.10 / g
99.00%
Dideu Industries Group Limited

4-Bromo-2-trifluoromethoxyaniline
175278-09-8
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

4-Bromo-2-trifluoromethoxyaniline
175278-09-8
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

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BUTTPARK 50\01-74 TIMTEC-BB SBB005835 2-AMINO-5-BROMO TRIFLUOROMETHOXY BENZENE 4-bromo-2-(trifluoromrthoxy)aniline 4-Bromo-2-(trifluoromethoxy)aniline 98% 4-Bromo-2-(trifluoromethoxy)aniline98% 4-Bromo-2-trifluoromethoxyaniline,97% 4-Bromo-2-(trifluoeomethoxy)aniline 4-Bromo-2-Trifluoromethox 1-Amino-4-bromo-2-(trifluoromethoxy)benzene 2-Amino-5-bromo-alpha,alpha,alpha-trifluoroanisole 2-Amino-5-bromo-alpha,alpha,alpha-trifluoroanisole, 2-Amino-5-bromophenyl trifluoromethyl ether 4-Bromo-2-(trifluoromethoxy)aniline > Benzenamine, 4-bromo-2-(trifluoromethoxy)- 1-Amino-4-bromo-2-(trifluoromethoxy)benzene 4-Bromo-2-trifluoromethoxyaniline ISO 9001：2015 REACH 4-BROMO-2-(TRIFLUOROMETHOXY)ANILINE 4-Bromo-2-trifluoromethoxy-phenylamine 2-trifluoromethoxy-4-bromoaniline 175278-09-8 C7H5BrF4O C7H5BrF3NO C7 Building Blocks Amines Organic Building Blocks Nitrogen Compounds ARYL AMINE Fluorine series Nitrogen Compounds Organic Building Blocks Building Blocks Chemical Synthesis Amines C7 Nitrogen Compounds Anilines, Aromatic Amines and Nitro Compounds Trifluoroanisole series