ANTI-DHP RECEPTOR ALPHA2
- CAS No.
- Chemical Name:
- ANTI-DHP RECEPTOR ALPHA2
- Synonyms
- ANTI-DHP RECEPTOR ALPHA2;ANTI-DIHYDROPYRIDINE RECEPTOR ALPHA-2;ANTI-DIHYDROPYRIDINE RECEPTOR (ALPHA2 SUBUNIT);Monoclonal Anti-Dihydropyridine Receptor (α2 Subunit) antibody produced in mouse
- CBNumber:
- CB8450027
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD01323189
- MOL File:
- Mol file
ANTI-DHP RECEPTOR ALPHA2 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D219 | Monoclonal Anti-Dihydropyridine Receptor (α2 Subunit) antibody produced in mouse clone 20A, ascites fluid, buffered aqueous solution | 100μL | $742 | 2024-03-01 | Buy |
| Product number | Packaging | Price | Buy |
|---|---|---|---|
| D219 | 100μL | $742 | Buy |
ANTI-DHP RECEPTOR ALPHA2 Chemical Properties,Uses,Production
Uses
Use of this antibody for immunoblot analysis will allow for detection of a 220 kDa band (native conditions) or a 143 kDa band (denaturing conditions).Use of this antibody for immunohistochemistry of muscle tissue will demonstrate double rows of discrete punctate staining representing pairs of triads on the opposing sides of the Z-lines are observed.
General Description
Dihydropyridine Receptor (DHPR) is a heteropentamer calcium ion channel and comprises of α1,α2/δ,β?and?γ?subunits. It is localized in the skeletal muscle in the t-tubule membrane. The α2subunit of DHPR is a glycosylated subunit and is anchored on the membrane.
Biochem/physiol Actions
Dihydropyridine Receptor (DHFR) α1?subunit is the voltage-sensor. DHPR interacts with ryanodine receptor (RyR) and also mediates excitation-contraction (EC) coupling in cardiac and skeletal muscles. Mutation in the DHPR (E1014K) affects its affinity and selectivity towards calcium permeation. Additionally, it also plays a key role in the synaptic transmission.
ANTI-DHP RECEPTOR ALPHA2 Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-DHP RECEPTOR ALPHA2 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Riedel-de Haen AG | -- | United States | 6825 | 87 | |
| SIGMA-RBI | -- | Switzerland | 6913 | 91 | |
| ABR-Affinity BioReagents | -- | affinity@bioreagents.com | United States | 489 | 73 |
| Alexis Corporation | -- | alexis-ch@alexis-corp.ch | Switzerland | 3599 | 74 |
| Supplier | Advantage |
|---|---|
| Riedel-de Haen AG | 87 |
| SIGMA-RBI | 91 |
| ABR-Affinity BioReagents | 73 |
| Alexis Corporation | 74 |