18:1 PHOSPHATIDYLBUTANOL

Uses

18:1 Phosphatidylbutanol or 1,2-dioleoyl-sn-glycero-3-phosphobutanol (sodium salt) may be used:

• to monitor the changes in phosphatidic acid (PA) dynamics in pollen tube after pharmacological treatments
• as an internal standard for extraction of phospholipids from whole blood
• as a standard to measure phospholipase D (PLD) activity in rat 2 fibroblasts by thin layer chromatograpghy (TLC)

Uses

18:1 Phosphatidylbutanol or 1,2-dioleoyl-sn-glycero-3-phosphobutanol (sodium salt) has been used as a standard to measure phospholipase D (PLD) activity in smooth muscle cells (SMCs) and cancer cell lines by thin layer-chromatography.

General Description

Phosphatidylbutanol is a low polarity phosphatidylalcohol. This phospholipid is synthesized by the phospholipase D (PLD) catalyzed transphosphatidylation reaction of phosphatidylcholine (PC) and butanol.

Biochem/physiol Actions

Phosphatidylbutanol is used in phospholipase D activity assays as a potential biomarker.